{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Vascular+Endothelial+Function&page=12",
    "query": {
      "condition": "Vascular Endothelial Function",
      "page": 12
    },
    "page_size": 10
  },
  "pagination": {
    "page": 12,
    "page_size": 10,
    "total_count": 265,
    "total_pages": 27,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Vascular+Endothelial+Function&page=13&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Vascular+Endothelial+Function&page=11&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-19T23:42:39.681Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03824041",
      "title": "Effects of Aronia Berries on Vascular Endothelial Function and the Gut Microbiota in Middle-Aged/Older Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Endothelial Dysfunction",
        "Aging"
      ],
      "interventions": [
        {
          "name": "Aronia full spectrum - half dose",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Aronia full spectrum - full dose",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Colorado State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "45 Years to 75 Years"
      },
      "enrollment_count": 24,
      "start_date": "2019-02-11",
      "completion_date": "2021-07-26",
      "has_results": false,
      "last_update_posted_date": "2023-07-03",
      "last_synced_at": "2026-10-19T23:42:39.681Z",
      "location_count": 1,
      "location_summary": "Fort Collins, Colorado",
      "locations": [
        {
          "city": "Fort Collins",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03824041"
    },
    {
      "nct_id": "NCT01371370",
      "title": "Low-intensity Resistance Exercise and Diet on Arterial Function and Blood Pressure",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity",
        "Pre-hypertension",
        "Hypertension"
      ],
      "interventions": [
        {
          "name": "Resistance exercise training",
          "type": "OTHER"
        },
        {
          "name": "Hypocaloric diet",
          "type": "OTHER"
        },
        {
          "name": "Resistance exercise training & diet",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Florida State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "65 Years",
        "sex": "FEMALE",
        "summary": "40 Years to 65 Years · Female only"
      },
      "enrollment_count": 41,
      "start_date": "2010-12",
      "completion_date": "2012-06",
      "has_results": false,
      "last_update_posted_date": "2014-08-05",
      "last_synced_at": "2026-10-19T23:42:39.681Z",
      "location_count": 1,
      "location_summary": "Tallahassee, Florida",
      "locations": [
        {
          "city": "Tallahassee",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01371370"
    },
    {
      "nct_id": "NCT03072628",
      "title": "E-cigarettes, Nicotine Inhaler, and Blood Vessel Function",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Nicotine Dependence"
      ],
      "interventions": [
        {
          "name": "e-cig with nicotine",
          "type": "OTHER"
        },
        {
          "name": "e-cig without nicotine",
          "type": "OTHER"
        },
        {
          "name": "nicotine inhaler",
          "type": "OTHER"
        },
        {
          "name": "sham control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "21 Years to 45 Years"
      },
      "enrollment_count": 148,
      "start_date": "2017-01-11",
      "completion_date": "2022-12-01",
      "has_results": false,
      "last_update_posted_date": "2023-10-04",
      "last_synced_at": "2026-10-19T23:42:39.681Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03072628"
    },
    {
      "nct_id": "NCT00759291",
      "title": "The Impact of Free Fatty Acid Reduction on Vascular Function in the Metabolic Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Metabolic Syndrome"
      ],
      "interventions": [
        {
          "name": "acipimox",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2006-04-01",
      "completion_date": "2017-12-30",
      "has_results": true,
      "last_update_posted_date": "2023-02-21",
      "last_synced_at": "2026-10-19T23:42:39.681Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00759291"
    },
    {
      "nct_id": "NCT00108238",
      "title": "Estrogen Alternatives Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "Estradiol followed by progesterone",
          "type": "DRUG"
        },
        {
          "name": "Raloxifene",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "US Department of Veterans Affairs",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "Female only"
      },
      "enrollment_count": null,
      "start_date": "2003-04",
      "completion_date": "2006-12",
      "has_results": false,
      "last_update_posted_date": "2009-01-21",
      "last_synced_at": "2026-10-19T23:42:39.681Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00108238"
    },
    {
      "nct_id": "NCT00782015",
      "title": "Effects of Almonds on Vascular Reactivity in Patients With Coronary Artery Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Vascular Disease",
        "Endothelial Dysfunction",
        "Heart Disease",
        "Cardiovascular Diseases",
        "Hypertension"
      ],
      "interventions": [
        {
          "name": "Almonds",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo Comparator:",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Tufts University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "20 Years to 80 Years"
      },
      "enrollment_count": 45,
      "start_date": "2008-10",
      "completion_date": "2011-01",
      "has_results": false,
      "last_update_posted_date": "2017-04-28",
      "last_synced_at": "2026-10-19T23:42:39.681Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00782015"
    },
    {
      "nct_id": "NCT03112226",
      "title": "Effects of Ovarian Hormone Suppression on Vascular and Cognitive Function",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cognitive Impairment",
        "Estrogen Deficiency",
        "Menopause",
        "Endothelial Dysfunction",
        "Vascular Stiffness"
      ],
      "interventions": [
        {
          "name": "GnRHant + E2",
          "type": "OTHER"
        },
        {
          "name": "GnRHant + Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 50 Years · Female only"
      },
      "enrollment_count": 19,
      "start_date": "2018-02-07",
      "completion_date": "2020-06-21",
      "has_results": false,
      "last_update_posted_date": "2021-06-07",
      "last_synced_at": "2026-10-19T23:42:39.681Z",
      "location_count": 2,
      "location_summary": "Aurora, Colorado • Boulder, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Boulder",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03112226"
    },
    {
      "nct_id": "NCT02099578",
      "title": "The Effects of Strawberries on Blood Pressure in Postmenopausal Women",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hypertension",
        "Cardiovascular Diseases",
        "Vascular Diseases"
      ],
      "interventions": [
        {
          "name": "25 g of Freeze-dried Strawberry Powder",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "50 g of Freeze-dried Strawberry Powder",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo Powder",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Florida State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "65 Years",
        "sex": "FEMALE",
        "summary": "45 Years to 65 Years · Female only"
      },
      "enrollment_count": 60,
      "start_date": "2013-02",
      "completion_date": "2014-07",
      "has_results": false,
      "last_update_posted_date": "2016-12-16",
      "last_synced_at": "2026-10-19T23:42:39.681Z",
      "location_count": 1,
      "location_summary": "Tallahassee, Florida",
      "locations": [
        {
          "city": "Tallahassee",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02099578"
    },
    {
      "nct_id": "NCT04525443",
      "title": "Endothelial Function and COVID-19",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "COVID-19"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Hospital San Carlos, Madrid",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 110,
      "start_date": "2020-06-03",
      "completion_date": "2021-02-11",
      "has_results": false,
      "last_update_posted_date": "2021-02-26",
      "last_synced_at": "2026-10-19T23:42:39.681Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04525443"
    },
    {
      "nct_id": "NCT01114360",
      "title": "Melatonin and Nighttime Blood Pressure in African Americans-8 mg Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Hypertension"
      ],
      "interventions": [
        {
          "name": "Melatonin",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "18 Years to 64 Years"
      },
      "enrollment_count": 37,
      "start_date": "2010-03",
      "completion_date": "2014-09",
      "has_results": true,
      "last_update_posted_date": "2015-12-18",
      "last_synced_at": "2026-10-19T23:42:39.681Z",
      "location_count": 1,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01114360"
    }
  ]
}