{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Vasomotor+Disturbance",
    "query": {
      "condition": "Vasomotor Disturbance"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 5,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T05:43:54.334Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02040532",
      "title": "Gabapentin for Insomnia Symptoms and Nighttime Vasomotor Symptoms (VMS) in Peri- and Postmenopausal Women",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Menopause",
        "Hot Flashes",
        "Vasomotor Disturbance"
      ],
      "interventions": [
        {
          "name": "Gabapentin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "65 Years",
        "sex": "FEMALE",
        "summary": "40 Years to 65 Years · Female only"
      },
      "enrollment_count": 32,
      "start_date": "2014-01",
      "completion_date": "2015-08",
      "has_results": true,
      "last_update_posted_date": "2019-08-07",
      "last_synced_at": "2026-05-22T05:43:54.334Z",
      "location_count": 2,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02040532"
    },
    {
      "nct_id": "NCT01936441",
      "title": "MsFLASH-04: Pilot Trial: Telephone Behavioral Therapy for Menopause-related Sleep Disturbance",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hot Flashes",
        "Menopause",
        "Vasomotor Disturbance",
        "Sleep"
      ],
      "interventions": [
        {
          "name": "Cognitive Behavioral Therapy-Insomnia (CBT-I)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Menopause Education Control (MEC)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Fred Hutchinson Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "65 Years",
        "sex": "FEMALE",
        "summary": "40 Years to 65 Years · Female only"
      },
      "enrollment_count": 106,
      "start_date": "2013-11",
      "completion_date": "2015-06",
      "has_results": false,
      "last_update_posted_date": "2015-10-22",
      "last_synced_at": "2026-05-22T05:43:54.334Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01936441"
    },
    {
      "nct_id": "NCT02234362",
      "title": "Vortioxetine for Menopausal Depression",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Depression",
        "Menopause",
        "Vasomotor Disturbance",
        "Hot Flashes",
        "Sleep"
      ],
      "interventions": [
        {
          "name": "vortioxetine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "62 Years",
        "sex": "FEMALE",
        "summary": "40 Years to 62 Years · Female only"
      },
      "enrollment_count": 47,
      "start_date": "2015-06-12",
      "completion_date": "2016-09-29",
      "has_results": true,
      "last_update_posted_date": "2017-06-28",
      "last_synced_at": "2026-05-22T05:43:54.334Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02234362"
    },
    {
      "nct_id": "NCT01418209",
      "title": "MsFLASH-03: Comparative Efficacy of Low-Dose Estradiol and Venlafaxine XR for Treatment of Menopausal Symptoms",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hot Flashes",
        "Menopause",
        "Vasomotor Disturbance"
      ],
      "interventions": [
        {
          "name": "Low-dose 17-ß-estradiol with progesterone taper",
          "type": "DRUG"
        },
        {
          "name": "Venlafaxine XR",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Fred Hutchinson Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "62 Years",
        "sex": "FEMALE",
        "summary": "40 Years to 62 Years · Female only"
      },
      "enrollment_count": 339,
      "start_date": "2011-11",
      "completion_date": "2013-01",
      "has_results": true,
      "last_update_posted_date": "2014-08-27",
      "last_synced_at": "2026-05-22T05:43:54.334Z",
      "location_count": 4,
      "location_summary": "Boston, Massachusetts • Chestnut Hill, Massachusetts • Philadelphia, Pennsylvania + 1 more",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Chestnut Hill",
          "state": "Massachusetts"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01418209"
    },
    {
      "nct_id": "NCT06957691",
      "title": "Proof-of-Concept Trial to Assess the Efficacy and Safety of Fezolinetant in Improving Vasomotor Symptoms in Men With Prostate Cancer Undergoing Androgen Deprivation Therapy",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Prostate Cancer",
        "Prostate Cancer (Adenocarcinoma)",
        "Prostate Cancer Metastatic Disease",
        "Prostate Cancer Recurrent",
        "Prostate Carcinoma",
        "Prostate Neoplasm",
        "Prostate Adenocarcinoma",
        "Prostate Cancer With Bone Metastasis",
        "Vasomotor Disturbance",
        "Vasomotor Symptoms",
        "Vasomotor Symptoms (VMS)",
        "Vasomotor Symptoms as a Sex Hormone-dependent Disorder in Women and Men",
        "Vasomotor Symptoms; Hot Flashes",
        "Androgen Deprivation Therapy",
        "Androgen Ablative Therapy of Advanced Hormone-dependent Prostate Carcinoma",
        "Androgen-deprivation Therapy",
        "Hot Flashes",
        "Hot Flushes",
        "Hot Flushes and/or Sweats"
      ],
      "interventions": [
        {
          "name": "fezolinetant - reference formulation",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Shehzad Basaria, M.D.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "MALE",
        "summary": "40 Years and older · Male only"
      },
      "enrollment_count": 60,
      "start_date": "2026-01-14",
      "completion_date": "2028-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-03-09",
      "last_synced_at": "2026-05-22T05:43:54.334Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06957691"
    }
  ]
}