{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Vasomotor+System",
    "query": {
      "condition": "Vasomotor System"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 13,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Vasomotor+System&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-10T13:59:05.697Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03512002",
      "title": "HIRREM Hot Flashes Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Vasomotor Symptoms",
        "Hot Flashes",
        "Menopause"
      ],
      "interventions": [
        {
          "name": "HIRREM",
          "type": "DEVICE"
        },
        {
          "name": "Continued Current Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "40 Years and older · Female only"
      },
      "enrollment_count": 8,
      "start_date": "2018-06-01",
      "completion_date": "2020-05-27",
      "has_results": true,
      "last_update_posted_date": "2023-05-23",
      "last_synced_at": "2026-06-10T13:59:05.697Z",
      "location_count": 1,
      "location_summary": "Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03512002"
    },
    {
      "nct_id": "NCT05071729",
      "title": "A Study to Learn How Elinzanetant Moves Into, Through, and Out of the Body, How Safe it is, and How it Affects the Body in Participants With Kidneys That do Not Work as Well as They Should Compared to Participants Whose Kidneys Work Normally",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Vasomotor Symptoms as a Sex Hormone-dependent Disorder in Women and Men"
      ],
      "interventions": [
        {
          "name": "Elinzanetant (BAY3427080)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Bayer",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "79 Years",
        "sex": "ALL",
        "summary": "18 Years to 79 Years"
      },
      "enrollment_count": 31,
      "start_date": "2021-10-14",
      "completion_date": "2022-10-19",
      "has_results": false,
      "last_update_posted_date": "2025-07-14",
      "last_synced_at": "2026-06-10T13:59:05.697Z",
      "location_count": 2,
      "location_summary": "Miami, Florida • Orlando, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05071729"
    },
    {
      "nct_id": "NCT02553655",
      "title": "Remote Ischemic Limb Preconditioning In Healthy Volunteers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cerebrovascular Disease",
        "Stroke"
      ],
      "interventions": [
        {
          "name": "4x 5min Limb Preconditioning",
          "type": "PROCEDURE"
        },
        {
          "name": "3x 10min Limb Preconditioning",
          "type": "PROCEDURE"
        },
        {
          "name": "3x 10min Sham Preconditioning",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Miami",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 17,
      "start_date": "2015-10",
      "completion_date": "2021-06-03",
      "has_results": false,
      "last_update_posted_date": "2021-09-13",
      "last_synced_at": "2026-06-10T13:59:05.697Z",
      "location_count": 1,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02553655"
    },
    {
      "nct_id": "NCT00369434",
      "title": "Study of the Safety and Efficacy of Desvenlafaxine Succinate for Vasomotor Symptoms in Postmenopausal Women",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Menopause",
        "Vasomotor System"
      ],
      "interventions": [
        {
          "name": "Desvenlafaxine succinate sustained-release (DVS SR)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Wyeth is now a wholly owned subsidiary of Pfizer",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "Female only"
      },
      "enrollment_count": 450,
      "start_date": "2006-06",
      "completion_date": "2007-02",
      "has_results": false,
      "last_update_posted_date": "2007-06-01",
      "last_synced_at": "2026-06-10T13:59:05.697Z",
      "location_count": 34,
      "location_summary": "Montgomery, Alabama • Peoria, Arizona • Upland, California + 31 more",
      "locations": [
        {
          "city": "Montgomery",
          "state": "Alabama"
        },
        {
          "city": "Peoria",
          "state": "Arizona"
        },
        {
          "city": "Upland",
          "state": "California"
        },
        {
          "city": "Colorado Springs",
          "state": "Colorado"
        },
        {
          "city": "Brooksville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00369434"
    },
    {
      "nct_id": "NCT00950781",
      "title": "Cortisol Levels on Menopausal Symptoms - Ancillary (Addendum) Study to Protocol 16997",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Menopause"
      ],
      "interventions": [
        {
          "name": "ACTH",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Cedars-Sinai Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "70 Years",
        "sex": "FEMALE",
        "summary": "40 Years to 70 Years · Female only"
      },
      "enrollment_count": 45,
      "start_date": "2009-01",
      "completion_date": "2010-02",
      "has_results": false,
      "last_update_posted_date": "2019-06-07",
      "last_synced_at": "2026-06-10T13:59:05.697Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00950781"
    },
    {
      "nct_id": "NCT00369343",
      "title": "Study Evaluating Desvenlafaxine Succinate Sustained Release (DVS SR) Versus Placebo in Peri- and Postmenopausal Women",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Depression",
        "Depressive Disorder",
        "Depressive Disorder, Major"
      ],
      "interventions": [
        {
          "name": "Desvenlafaxine administered as a succinate salt in a sustained-release form (DVS SR)",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Wyeth is now a wholly owned subsidiary of Pfizer",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "70 Years",
        "sex": "FEMALE",
        "summary": "40 Years to 70 Years · Female only"
      },
      "enrollment_count": 381,
      "start_date": "2006-09",
      "completion_date": "2008-07",
      "has_results": true,
      "last_update_posted_date": "2012-05-07",
      "last_synced_at": "2026-06-10T13:59:05.697Z",
      "location_count": 37,
      "location_summary": "Birmingham, Alabama • Little Rock, Arkansas • Springdale, Arkansas + 33 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Springdale",
          "state": "Arkansas"
        },
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00369343"
    },
    {
      "nct_id": "NCT06957691",
      "title": "Proof-of-Concept Trial to Assess the Efficacy and Safety of Fezolinetant in Improving Vasomotor Symptoms in Men With Prostate Cancer Undergoing Androgen Deprivation Therapy",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Prostate Cancer",
        "Prostate Cancer (Adenocarcinoma)",
        "Prostate Cancer Metastatic Disease",
        "Prostate Cancer Recurrent",
        "Prostate Carcinoma",
        "Prostate Neoplasm",
        "Prostate Adenocarcinoma",
        "Prostate Cancer With Bone Metastasis",
        "Vasomotor Disturbance",
        "Vasomotor Symptoms",
        "Vasomotor Symptoms (VMS)",
        "Vasomotor Symptoms as a Sex Hormone-dependent Disorder in Women and Men",
        "Vasomotor Symptoms; Hot Flashes",
        "Androgen Deprivation Therapy",
        "Androgen Ablative Therapy of Advanced Hormone-dependent Prostate Carcinoma",
        "Androgen-deprivation Therapy",
        "Hot Flashes",
        "Hot Flushes",
        "Hot Flushes and/or Sweats"
      ],
      "interventions": [
        {
          "name": "fezolinetant - reference formulation",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Shehzad Basaria, M.D.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "MALE",
        "summary": "40 Years and older · Male only"
      },
      "enrollment_count": 60,
      "start_date": "2026-01-14",
      "completion_date": "2028-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-03-09",
      "last_synced_at": "2026-06-10T13:59:05.697Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06957691"
    },
    {
      "nct_id": "NCT05351892",
      "title": "A Study to Learn More About How Much of the Study Treatment Elinzanetant (or BAY3427080) Gets Absorbed, How Safe it is and How it Affects the Body in Healthy Female and Male Participants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Vasomotor Symptoms as a Sex Hormone-dependent Disorder in Women and Men",
        "Hot Flashes",
        "Healthy Volunteers"
      ],
      "interventions": [
        {
          "name": "Elinzanetant (BAY3427080)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Bayer",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 18,
      "start_date": "2022-05-04",
      "completion_date": "2022-06-20",
      "has_results": false,
      "last_update_posted_date": "2022-07-19",
      "last_synced_at": "2026-06-10T13:59:05.697Z",
      "location_count": 1,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05351892"
    },
    {
      "nct_id": "NCT05193968",
      "title": "Hot Flashes and Neurovascular Function in Women",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hot Flashes",
        "Menopause",
        "Vasomotor System; Labile"
      ],
      "interventions": [
        {
          "name": "Sympathoexcitatory stressors",
          "type": "OTHER"
        },
        {
          "name": "Sodium Nitroprusside",
          "type": "DRUG"
        },
        {
          "name": "Acetylcholine",
          "type": "DRUG"
        },
        {
          "name": "Terbutaline",
          "type": "DRUG"
        },
        {
          "name": "Norepinephrine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DRUG"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "60 Years",
        "sex": "FEMALE",
        "summary": "40 Years to 60 Years · Female only"
      },
      "enrollment_count": 120,
      "start_date": "2022-02-24",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2025-06-03",
      "last_synced_at": "2026-06-10T13:59:05.697Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05193968"
    },
    {
      "nct_id": "NCT00808535",
      "title": "Cardiac Magnetic Resonance Imaging for Detecting Endothelial Dysfunction",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Endothelial Dysfunction",
        "Myocardial Perfusion Abnormalities",
        "Cardiac MRI Perfusion With Vasomotor Stress",
        "Diabetes"
      ],
      "interventions": [
        {
          "name": "Cardiac Perfusion MRI w Vasomotor Stress",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of California, Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 60,
      "start_date": "2009-02",
      "completion_date": "2010-03",
      "has_results": false,
      "last_update_posted_date": "2009-02-09",
      "last_synced_at": "2026-06-10T13:59:05.697Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00808535"
    }
  ]
}