{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Venous+Leg",
    "query": {
      "condition": "Venous Leg"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 239,
    "total_pages": 24,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Venous+Leg&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T19:42:14.171Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02988063",
      "title": "Effect of PEM Treatment of Superficial Axial and Tributary Vein Reflux on Improvement of Wound Healing in VLUs",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Leg Ulcer",
        "Veins, Varicose",
        "Venous Ulcer",
        "Reflux",
        "Venous Reflux",
        "Venous Leg Ulcer",
        "Varicose Veins",
        "Varicose Ulcer",
        "Varicose Veins Leg"
      ],
      "interventions": [
        {
          "name": "Polidocanol Endovenous Microfoam (PEM)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "OhioHealth",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2017-04-10",
      "completion_date": "2017-09-12",
      "has_results": false,
      "last_update_posted_date": "2017-09-15",
      "last_synced_at": "2026-07-23T19:42:14.171Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02988063"
    },
    {
      "nct_id": "NCT03903692",
      "title": "A Comparative Evaluation of a MPS Dressing and a CMC Dressing on Subjects With Lower Extremity Venous Ulcers",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Venous Leg Ulcer"
      ],
      "interventions": [
        {
          "name": "Marine polysaccharide dressing",
          "type": "DEVICE"
        },
        {
          "name": "Carboxymethylcellulose dressing",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Medline Industries",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 62,
      "start_date": "2019-09-30",
      "completion_date": "2022-12-21",
      "has_results": true,
      "last_update_posted_date": "2024-06-25",
      "last_synced_at": "2026-07-23T19:42:14.171Z",
      "location_count": 5,
      "location_summary": "Fresno, California • Selma, California • Boston, Massachusetts + 2 more",
      "locations": [
        {
          "city": "Fresno",
          "state": "California"
        },
        {
          "city": "Selma",
          "state": "California"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Saginaw",
          "state": "Michigan"
        },
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03903692"
    },
    {
      "nct_id": "NCT02939599",
      "title": "Long-term Extension Study of the Safety and Pharmacokinetics of QCC374 in PAH Patients",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Pulmonary Arterial Hypertension"
      ],
      "interventions": [
        {
          "name": "QCC374",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Novartis Pharmaceuticals",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 5,
      "start_date": "2018-02-01",
      "completion_date": "2018-11-06",
      "has_results": true,
      "last_update_posted_date": "2021-01-05",
      "last_synced_at": "2026-07-23T19:42:14.171Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02939599"
    },
    {
      "nct_id": "NCT02930499",
      "title": "Effect of Hyaluronic Acid ECM on Venous Ulcers",
      "overall_status": "SUSPENDED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Venous Ulcers"
      ],
      "interventions": [
        {
          "name": "Hyalomatrix extra-cellular matrix",
          "type": "DEVICE"
        },
        {
          "name": "Mepilex wound dressing",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Calvary Hospital, Bronx, NY",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "21 Years to 90 Years"
      },
      "enrollment_count": 20,
      "start_date": "2016-01",
      "completion_date": "2018-12",
      "has_results": false,
      "last_update_posted_date": "2017-03-30",
      "last_synced_at": "2026-07-23T19:42:14.171Z",
      "location_count": 1,
      "location_summary": "Newark, New Jersey",
      "locations": [
        {
          "city": "Newark",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02930499"
    },
    {
      "nct_id": "NCT06811909",
      "title": "Non-healing Venous Leg Ulcers Treated With Standard Care With or Without BR-AC",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Non-infected Venous Leg Ulcer",
        "Venous Leg Ulcer",
        "Venous Insufficiency",
        "Venous Stasis",
        "Venous Reflux"
      ],
      "interventions": [
        {
          "name": "BR-AC",
          "type": "OTHER"
        },
        {
          "name": "Standard Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "BioStem Technologies",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2025-02-14",
      "completion_date": "2026-10",
      "has_results": false,
      "last_update_posted_date": "2026-01-23",
      "last_synced_at": "2026-07-23T19:42:14.171Z",
      "location_count": 23,
      "location_summary": "Guntersville, Alabama • Castro Valley, California • Glendale, California + 17 more",
      "locations": [
        {
          "city": "Guntersville",
          "state": "Alabama"
        },
        {
          "city": "Castro Valley",
          "state": "California"
        },
        {
          "city": "Glendale",
          "state": "California"
        },
        {
          "city": "Oxnard",
          "state": "California"
        },
        {
          "city": "Oxnard",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06811909"
    },
    {
      "nct_id": "NCT07102160",
      "title": "Cleaner Long-tErm Assessment Registry - Venous Insights and Efficacy With eXtended Tracking",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Deep Vein Thrombosis (DVT)",
        "Thrombus in the Peripheral Venous Vasculature",
        "Venous Embolism",
        "Thrombus in the Central and Peripheral Circulatory System, Including Saphenous Vein Grafts"
      ],
      "interventions": [
        {
          "name": "Aspiration thrombectomy system",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Argon Medical Devices",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 185,
      "start_date": "2026-02-04",
      "completion_date": "2029-06",
      "has_results": false,
      "last_update_posted_date": "2026-06-16",
      "last_synced_at": "2026-07-23T19:42:14.171Z",
      "location_count": 4,
      "location_summary": "Fort Lauderdale, Florida • Tampa, Florida • Edgewood, Kentucky + 1 more",
      "locations": [
        {
          "city": "Fort Lauderdale",
          "state": "Florida"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "Edgewood",
          "state": "Kentucky"
        },
        {
          "city": "Plano",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07102160"
    },
    {
      "nct_id": "NCT05628688",
      "title": "A Non-randomized, Open-Label Study to Evaluate the Safety and Effectiveness of Insight® Pro Device for Evaluating Lymphatic and Venous Disorders (VOLGA)",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Lymphedema",
        "Chronic Venous Insufficiency",
        "Edema",
        "Venous Insufficiency of Leg"
      ],
      "interventions": [
        {
          "name": "Insight Pro Device for Diagnosis",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Koya Medical, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 67,
      "start_date": "2023-08-08",
      "completion_date": "2025-12-04",
      "has_results": false,
      "last_update_posted_date": "2025-12-12",
      "last_synced_at": "2026-07-23T19:42:14.171Z",
      "location_count": 1,
      "location_summary": "Oakland, California",
      "locations": [
        {
          "city": "Oakland",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05628688"
    },
    {
      "nct_id": "NCT04690803",
      "title": "The Effect of Cooling on Sclerotherapy Efficacy",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Leg Veins"
      ],
      "interventions": [
        {
          "name": "air cooling",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Goldman, Butterwick, Fitzpatrick and Groff",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "25 Years to 75 Years"
      },
      "enrollment_count": 20,
      "start_date": "2020-01-06",
      "completion_date": "2022-12-01",
      "has_results": false,
      "last_update_posted_date": "2021-01-05",
      "last_synced_at": "2026-07-23T19:42:14.171Z",
      "location_count": 1,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04690803"
    },
    {
      "nct_id": "NCT03077165",
      "title": "Dose-response Relationship Study of S42909 on Leg Ulcer Healing",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Venous Leg Ulcer"
      ],
      "interventions": [
        {
          "name": "S42909 100 mg",
          "type": "DRUG"
        },
        {
          "name": "S42909 200 mg",
          "type": "DRUG"
        },
        {
          "name": "S42909 400 mg",
          "type": "DRUG"
        },
        {
          "name": "S42909 800 mg",
          "type": "DRUG"
        },
        {
          "name": "S42909 1200 mg",
          "type": "DRUG"
        },
        {
          "name": "Placebo Oral Tablet",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Ilkos Therapeutic Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 121,
      "start_date": "2017-09-12",
      "completion_date": "2020-01-22",
      "has_results": true,
      "last_update_posted_date": "2020-10-08",
      "last_synced_at": "2026-07-23T19:42:14.171Z",
      "location_count": 14,
      "location_summary": "Carlsbad, California • Carmichael, California • Castro Valley, California + 10 more",
      "locations": [
        {
          "city": "Carlsbad",
          "state": "California"
        },
        {
          "city": "Carmichael",
          "state": "California"
        },
        {
          "city": "Castro Valley",
          "state": "California"
        },
        {
          "city": "Fresno",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03077165"
    },
    {
      "nct_id": "NCT01509599",
      "title": "Cooling Lower Leg Skin to Prevent Venous Leg Ulcers in Patients With Poor Vein Circulation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Venous Disease",
        "Venous Vascular Diseases and Syndromes",
        "Venous Insufficiency",
        "Venous Ulcers"
      ],
      "interventions": [
        {
          "name": "Cryotherapy: Cooling gel wrap",
          "type": "PROCEDURE"
        },
        {
          "name": "Usual care",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Medical University of South Carolina",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 197,
      "start_date": "2011-08",
      "completion_date": "2015-12",
      "has_results": false,
      "last_update_posted_date": "2016-04-05",
      "last_synced_at": "2026-07-23T19:42:14.171Z",
      "location_count": 2,
      "location_summary": "Charleston, South Carolina • Spartanburg, South Carolina",
      "locations": [
        {
          "city": "Charleston",
          "state": "South Carolina"
        },
        {
          "city": "Spartanburg",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01509599"
    }
  ]
}