{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Ventilation+Perfusion+Mismatch",
    "query": {
      "condition": "Ventilation Perfusion Mismatch"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 6,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T09:04:53.355Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06512935",
      "title": "Ventilator Pressure and Optimization of Compliance and Hemodynamics",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Bronchopulmonary Dysplasia",
        "Pulmonary Hypertension Due to Lung Diseases and Hypoxia",
        "Extreme Prematurity",
        "Ventilator Lung; Newborn",
        "Ventilation Perfusion Mismatch"
      ],
      "interventions": [
        {
          "name": "Increase in the PEEP followed by decrease in the PEEP",
          "type": "OTHER"
        },
        {
          "name": "Decrease in the PEEP followed by increase in the PEEP",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "7 Days",
        "maximum_age": "30 Days",
        "sex": "ALL",
        "summary": "7 Days to 30 Days"
      },
      "enrollment_count": 24,
      "start_date": "2026-08-01",
      "completion_date": "2027-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-05-11",
      "last_synced_at": "2026-05-22T09:04:53.355Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06512935"
    },
    {
      "nct_id": "NCT03109613",
      "title": "PEEP and V/Q Mismatch in Premature Infants",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Respiratory Insufficiency Syndrome of Newborn",
        "Infant, Premature, Diseases"
      ],
      "interventions": [
        {
          "name": "Positive end-expiratory pressure (PEEP)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Children's Hospital of Philadelphia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "0 Days",
        "maximum_age": "28 Days",
        "sex": "ALL",
        "summary": "0 Days to 28 Days"
      },
      "enrollment_count": 12,
      "start_date": "2016-04-11",
      "completion_date": "2018-08-08",
      "has_results": false,
      "last_update_posted_date": "2020-11-17",
      "last_synced_at": "2026-05-22T09:04:53.355Z",
      "location_count": 3,
      "location_summary": "Newark, Delaware • Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Newark",
          "state": "Delaware"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03109613"
    },
    {
      "nct_id": "NCT02983825",
      "title": "Impact of CPAP Level on V/Q Mismatch in Premature Infants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Infant, Premature, Diseases",
        "Respiratory Insufficiency Syndrome of Newborn"
      ],
      "interventions": [
        {
          "name": "Continuous positive airway pressure (CPAP); level changes",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Children's Hospital of Philadelphia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "24 Hours",
        "maximum_age": "35 Weeks",
        "sex": "ALL",
        "summary": "24 Hours to 35 Weeks"
      },
      "enrollment_count": 21,
      "start_date": "2017-02-01",
      "completion_date": "2020-02-13",
      "has_results": true,
      "last_update_posted_date": "2021-03-25",
      "last_synced_at": "2026-05-22T09:04:53.355Z",
      "location_count": 3,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02983825"
    },
    {
      "nct_id": "NCT05801224",
      "title": "Vascular ARDS Recruitment After Inhaled Nitric Oxide",
      "overall_status": "SUSPENDED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Respiratory Distress Syndrome",
        "Ventilation Perfusion Mismatch"
      ],
      "interventions": [
        {
          "name": "Nitric Oxide",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 70,
      "start_date": "2026-07-01",
      "completion_date": "2028-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-05-08",
      "last_synced_at": "2026-05-22T09:04:53.355Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05801224"
    },
    {
      "nct_id": "NCT01943227",
      "title": "Effect of Alveolar Minute Ventilation on Respiratory Gas Heat Content",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Ventilation Perfusion Mismatch"
      ],
      "interventions": [
        {
          "name": "controlled positive pressure ventilation 9ml/kg tidal volume",
          "type": "OTHER"
        },
        {
          "name": "controlled positive pressure ventilation 6ml/kg tidal volume",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2013-08",
      "completion_date": "2014-03",
      "has_results": true,
      "last_update_posted_date": "2019-10-28",
      "last_synced_at": "2026-05-22T09:04:53.355Z",
      "location_count": 1,
      "location_summary": "Sacramento, California",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01943227"
    },
    {
      "nct_id": "NCT05866952",
      "title": "Ventilatory and Perfusion Abnormalities in Individuals With Post-Acute Sequelae of SARS-CoV-2 Infection",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Post-Acute COVID-19",
        "Post COVID-19 Condition",
        "Post Viral Fatigue",
        "Dyspnea"
      ],
      "interventions": [
        {
          "name": "Computed Tomography of the Chest",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Tufts Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 40,
      "start_date": "2023-06-05",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-07-20",
      "last_synced_at": "2026-05-22T09:04:53.355Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05866952"
    }
  ]
}