{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Ventricular+Septal+Defect&page=2",
    "query": {
      "condition": "Ventricular Septal Defect",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Ventricular+Septal+Defect&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T02:50:13.209Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00583791",
      "title": "Closure of Muscular Ventricular Septal Defects With The AMPLATZER™ Muscular VSD Occluder",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Heart Septal Defects, Ventricular"
      ],
      "interventions": [
        {
          "name": "Device closure with the AMPLATZER Muscular VSD Occluder",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Abbott Medical Devices",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 91,
      "start_date": "2000-07",
      "completion_date": "2009-11",
      "has_results": true,
      "last_update_posted_date": "2019-06-28",
      "last_synced_at": "2026-05-22T02:50:13.209Z",
      "location_count": 11,
      "location_summary": "Denver, Colorado • Orlando, Florida • Chicago, Illinois + 8 more",
      "locations": [
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00583791"
    },
    {
      "nct_id": "NCT00006272",
      "title": "Study of Energy Expenditure in Infants With Ventricular Septal Defects",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Heart Septal Defects, Ventricular"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Center for Research Resources (NCRR)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "3 Months",
        "maximum_age": "4 Months",
        "sex": "ALL",
        "summary": "3 Months to 4 Months"
      },
      "enrollment_count": 20,
      "start_date": "1994-08",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2005-06-24",
      "last_synced_at": "2026-05-22T02:50:13.209Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00006272"
    },
    {
      "nct_id": "NCT01825369",
      "title": "Aberrations in Carnitine Homeostasis in Congenital Heart Disease With Increased Pulmonary Blood Flow",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Heart Septal Defects, Ventricular",
        "Atrioventricular Septal Defect"
      ],
      "interventions": [
        {
          "name": "IV L-carnitine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Months",
        "maximum_age": "12 Months",
        "sex": "ALL",
        "summary": "2 Months to 12 Months"
      },
      "enrollment_count": 0,
      "start_date": "2014-12",
      "completion_date": "2020-07",
      "has_results": false,
      "last_update_posted_date": "2020-05-06",
      "last_synced_at": "2026-05-22T02:50:13.209Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01825369"
    },
    {
      "nct_id": "NCT00848393",
      "title": "Measures to Lower the Stress Response in Pediatric Cardiac Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Tetralogy of Fallot (TOF)",
        "Ventricular Septal Defects (VSD)",
        "Atrioventricular Septal Defects (AVSD)"
      ],
      "interventions": [
        {
          "name": "Fentanyl (High Dose)",
          "type": "DRUG"
        },
        {
          "name": "Fentanyl (Low Dose)",
          "type": "DRUG"
        },
        {
          "name": "Fentanyl (Low Dose) + Dexmedetomidine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Nationwide Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Month",
        "maximum_age": "3 Years",
        "sex": "ALL",
        "summary": "1 Month to 3 Years"
      },
      "enrollment_count": 52,
      "start_date": "2008-11",
      "completion_date": "2013-12",
      "has_results": true,
      "last_update_posted_date": "2018-07-27",
      "last_synced_at": "2026-05-22T02:50:13.209Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00848393"
    },
    {
      "nct_id": "NCT03887286",
      "title": "Focused Cardiac Ultrasound",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ventricular Dysfunction",
        "Pericardial Effusion",
        "Valvular Disease",
        "Septal Defect"
      ],
      "interventions": [
        {
          "name": "Philips EPIQ 7 ultrasound machine",
          "type": "DEVICE"
        },
        {
          "name": "Philips Lumify Broadband sector array transducer",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Miami",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 47,
      "start_date": "2019-04-01",
      "completion_date": "2019-05-30",
      "has_results": true,
      "last_update_posted_date": "2020-06-16",
      "last_synced_at": "2026-05-22T02:50:13.209Z",
      "location_count": 1,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03887286"
    },
    {
      "nct_id": "NCT04017975",
      "title": "Optical Tissue Identification for Myocardial Architecture",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Ventricular Septal Defect",
        "Complete Atrioventricular Canal",
        "Tetralogy of Fallot With Pulmonary Stenosis"
      ],
      "interventions": [
        {
          "name": "Fluorescite",
          "type": "DRUG"
        },
        {
          "name": "Cellvizio 100 Series System with Confocal Miniprobes",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Aditya Kaza",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Days",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "30 Days to 18 Years"
      },
      "enrollment_count": 70,
      "start_date": "2019-12-20",
      "completion_date": "2023-09",
      "has_results": false,
      "last_update_posted_date": "2023-06-15",
      "last_synced_at": "2026-05-22T02:50:13.209Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04017975"
    },
    {
      "nct_id": "NCT04713657",
      "title": "Beta-blocker Administration for Cardiomyocyte Division",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Tetralogy of Fallot",
        "Double Outlet Right Ventricle"
      ],
      "interventions": [
        {
          "name": "N-thymidine",
          "type": "OTHER"
        },
        {
          "name": "Urine Collection",
          "type": "OTHER"
        },
        {
          "name": "Echocardiogram",
          "type": "PROCEDURE"
        },
        {
          "name": "Cardiac MRI (CMR)",
          "type": "PROCEDURE"
        },
        {
          "name": "Propranolol Hydrochloride",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "Physical Exam",
          "type": "PROCEDURE"
        },
        {
          "name": "Specimen Collection",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER",
        "PROCEDURE",
        "DRUG"
      ],
      "sponsor": "Weill Medical College of Cornell University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Days",
        "maximum_age": "60 Days",
        "sex": "ALL",
        "summary": "30 Days to 60 Days"
      },
      "enrollment_count": 40,
      "start_date": "2022-12-16",
      "completion_date": "2030-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-11-18",
      "last_synced_at": "2026-05-22T02:50:13.209Z",
      "location_count": 3,
      "location_summary": "New York, New York • Philadelphia, Pennsylvania • Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04713657"
    },
    {
      "nct_id": "NCT01120964",
      "title": "Intravenous L-Citrulline to Treat Children Undergoing Heart Bypass Surgery : Revised Protocol",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Atrial Septal Defect",
        "Ventricular Septal Defect",
        "Atrioventricular Septal Defect"
      ],
      "interventions": [
        {
          "name": "Intravenous L-Citrulline",
          "type": "DRUG"
        },
        {
          "name": "Placebo of Intravenous L-Citrulline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Asklepion Pharmaceuticals, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "6 Years",
        "sex": "ALL",
        "summary": "Up to 6 Years"
      },
      "enrollment_count": 22,
      "start_date": "2010-09",
      "completion_date": "2012-04",
      "has_results": true,
      "last_update_posted_date": "2022-07-27",
      "last_synced_at": "2026-05-22T02:50:13.209Z",
      "location_count": 2,
      "location_summary": "St Louis, Missouri • Cincinnati, Ohio",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01120964"
    },
    {
      "nct_id": "NCT01915277",
      "title": "A Phase I Study of Dexmedetomidine Bolus and Infusion in Corrective Infant Cardiac Surgery: Safety and Pharmacokinetics",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Transposition of the Great Arteries",
        "Tetralogy of Fallot",
        "Ventricular Septal Defect"
      ],
      "interventions": [
        {
          "name": "Dexmedetomidine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Carelon Research",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "180 Days",
        "sex": "ALL",
        "summary": "Up to 180 Days"
      },
      "enrollment_count": 119,
      "start_date": "2014-04-02",
      "completion_date": "2017-10-17",
      "has_results": false,
      "last_update_posted_date": "2018-03-23",
      "last_synced_at": "2026-05-22T02:50:13.209Z",
      "location_count": 4,
      "location_summary": "Boston, Massachusetts • Ann Arbor, Michigan • Philadelphia, Pennsylvania + 1 more",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01915277"
    },
    {
      "nct_id": "NCT00327795",
      "title": "Surgical Outcomes in Pediatric Patients With Coarctation and VSD",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Diagnosis of Coarctation of the Aorta and VSD",
        "Surgical Repair at CHOA",
        "Between January 1, 2002 and December 31, 2005"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Children's Healthcare of Atlanta",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 32,
      "start_date": "2006-01",
      "completion_date": "2007-11",
      "has_results": false,
      "last_update_posted_date": "2012-03-16",
      "last_synced_at": "2026-05-22T02:50:13.209Z",
      "location_count": 1,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00327795"
    }
  ]
}