{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Vertebra%3B+Degeneration",
    "query": {
      "condition": "Vertebra; Degeneration"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 30,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Vertebra%3B+Degeneration&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-27T08:57:46.840Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01372592",
      "title": "SpineTRACK Registry - Spinal Outcomes Registry",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Vertebra; Degeneration",
        "Spinal Trauma",
        "Spinal Deformity"
      ],
      "interventions": [
        {
          "name": "Surgery",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "NuVasive",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 8079,
      "start_date": "2011-03",
      "completion_date": "2016-12-06",
      "has_results": false,
      "last_update_posted_date": "2025-12-24",
      "last_synced_at": "2026-06-27T08:57:46.840Z",
      "location_count": 26,
      "location_summary": "Phoenix, Arizona • La Jolla, California • Orange, California + 22 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "Orange",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Durango",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01372592"
    },
    {
      "nct_id": "NCT04823858",
      "title": "3Spine Lumbar Fusion Real World Evidence Study",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Lumbar Spine Degeneration"
      ],
      "interventions": [
        {
          "name": "Lumbar Interbody Fusion",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "3Spine",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "21 Years to 80 Years"
      },
      "enrollment_count": 176,
      "start_date": "2021-05-25",
      "completion_date": "2029-11-15",
      "has_results": false,
      "last_update_posted_date": "2026-05-18",
      "last_synced_at": "2026-06-27T08:57:46.840Z",
      "location_count": 20,
      "location_summary": "Beverly Hills, California • Aurora, Colorado • Steamboat Springs, Colorado + 17 more",
      "locations": [
        {
          "city": "Beverly Hills",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Steamboat Springs",
          "state": "Colorado"
        },
        {
          "city": "Deerfield Beach",
          "state": "Florida"
        },
        {
          "city": "Temple Terrace",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04823858"
    },
    {
      "nct_id": "NCT04559295",
      "title": "Bone Marrow Concentrate (BMC) Injection in Intervertebral Discs",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Low Back Pain",
        "Disc Disease",
        "Disc Degeneration",
        "Arthropathy Vertebrae",
        "Sacral Disorder",
        "Radiculopathy",
        "Spinal Stenosis"
      ],
      "interventions": [
        {
          "name": "Bone Marrow Concentrate",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Stem Cures",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 80,
      "start_date": "2018-11-21",
      "completion_date": "2021-04-30",
      "has_results": false,
      "last_update_posted_date": "2020-09-22",
      "last_synced_at": "2026-06-27T08:57:46.840Z",
      "location_count": 1,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04559295"
    },
    {
      "nct_id": "NCT05746143",
      "title": "The Effect of Zolpidem on Outcomes Following Lumbar Spine Fusion",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Spine Fusion",
        "Lumbar Spine Degeneration",
        "Pain, Postoperative",
        "Lumbar Spine Spondylosis"
      ],
      "interventions": [
        {
          "name": "Zolpidem Tartrate 10 mg",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Southern California",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 140,
      "start_date": "2022-02-01",
      "completion_date": "2030-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-05-01",
      "last_synced_at": "2026-06-27T08:57:46.840Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05746143"
    },
    {
      "nct_id": "NCT05945550",
      "title": "Comparison of Complication Rates Between Initial and Re-operative Anterior Lumbar Interbody Fusion Surgery: Is There a Difference?",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Lumbar Spondylolisthesis",
        "Lumbar Spine Degeneration"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Methodist Health System",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 3500,
      "start_date": "2020-12-28",
      "completion_date": "2028-12-28",
      "has_results": false,
      "last_update_posted_date": "2026-03-20",
      "last_synced_at": "2026-06-27T08:57:46.840Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05945550"
    },
    {
      "nct_id": "NCT03088306",
      "title": "Improving Pain and Reducing Opioid Use (IPaRO) in Lumbar Spine Surgery Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Lumbar Spinal Stenosis",
        "Lumbar Spinal Instability",
        "Lumbar Spine Degeneration"
      ],
      "interventions": [
        {
          "name": "Standard analgesia use [Oxygen]",
          "type": "DRUG"
        },
        {
          "name": "Standard analgesia use [Hydromorphone]",
          "type": "DRUG"
        },
        {
          "name": "Standard analgesia use [Volatile Anesthesia]",
          "type": "DRUG"
        },
        {
          "name": "Standard analgesia use [Fentanyl]",
          "type": "DRUG"
        },
        {
          "name": "Multi-modal pain management [Acetaminophen + Gabapentin]",
          "type": "DRUG"
        },
        {
          "name": "Multi-modal pain management [Fentanyl]",
          "type": "DRUG"
        },
        {
          "name": "Multi-modal pain management [Intravenous Ketamine]",
          "type": "DRUG"
        },
        {
          "name": "Multi-modal pain management [Valium + Gabapentin]",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 49,
      "start_date": "2017-07-01",
      "completion_date": "2018-08-31",
      "has_results": false,
      "last_update_posted_date": "2018-10-16",
      "last_synced_at": "2026-06-27T08:57:46.840Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03088306"
    },
    {
      "nct_id": "NCT03527966",
      "title": "rhBMP-2 Versus Vivigen in Lumbar Fusion Procedures",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Lumbar Spine Degeneration"
      ],
      "interventions": [
        {
          "name": "5cc Vivigen and local autograft",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Small kit rhBMP-2 with local autograft",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Virtua Health, Inc.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 3,
      "start_date": "2017-07-03",
      "completion_date": "2018-07-27",
      "has_results": true,
      "last_update_posted_date": "2019-08-28",
      "last_synced_at": "2026-06-27T08:57:46.840Z",
      "location_count": 1,
      "location_summary": "Mount Holly, New Jersey",
      "locations": [
        {
          "city": "Mount Holly",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03527966"
    },
    {
      "nct_id": "NCT03176303",
      "title": "Study Using the SpinalStim Device Following Lumbar Fusion Surgery",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Lumbar Spine Degeneration"
      ],
      "interventions": [
        {
          "name": "SpinalStim",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Orthofix Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 206,
      "start_date": "2017-06-28",
      "completion_date": "2021-07-12",
      "has_results": false,
      "last_update_posted_date": "2022-09-16",
      "last_synced_at": "2026-06-27T08:57:46.840Z",
      "location_count": 1,
      "location_summary": "Johnstown, Colorado",
      "locations": [
        {
          "city": "Johnstown",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03176303"
    },
    {
      "nct_id": "NCT06475365",
      "title": "Salt Water Gargling on Swallowing Following ACDF",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Degeneration Spine",
        "Cervical Radiculopathy",
        "Cervical Stenosis",
        "Cervical Spondylosis",
        "Cervical Myelopathy",
        "Dysphagia"
      ],
      "interventions": [
        {
          "name": "Sodium chloride gargle",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Southern California",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 50,
      "start_date": "2024-12-10",
      "completion_date": "2025-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-07-18",
      "last_synced_at": "2026-06-27T08:57:46.840Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06475365"
    },
    {
      "nct_id": "NCT05438719",
      "title": "MOTUS Total Joint Replacement Investigational Device Exemption Study",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lumbar Spine Degeneration"
      ],
      "interventions": [
        {
          "name": "MOTUS Total Joint Replacement",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "3Spine",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "21 Years to 80 Years"
      },
      "enrollment_count": 158,
      "start_date": "2022-06-23",
      "completion_date": "2029-06-13",
      "has_results": false,
      "last_update_posted_date": "2026-05-22",
      "last_synced_at": "2026-06-27T08:57:46.840Z",
      "location_count": 14,
      "location_summary": "Los Angeles, California • Steamboat Springs, Colorado • Deerfield Beach, Florida + 11 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Steamboat Springs",
          "state": "Colorado"
        },
        {
          "city": "Deerfield Beach",
          "state": "Florida"
        },
        {
          "city": "Temple Terrace",
          "state": "Florida"
        },
        {
          "city": "Paducah",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05438719"
    }
  ]
}