{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Wrinkle&page=2",
    "query": {
      "condition": "Wrinkle",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Wrinkle&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T09:19:05.602Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02600104",
      "title": "Evaluate the Performance of the PicoWayTM Picosecond Fractional Laser for Wrinkles Reduction",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Unwanted Wrinkles"
      ],
      "interventions": [
        {
          "name": "PicoWayTM",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Syneron Medical",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 74,
      "start_date": "2015-06-10",
      "completion_date": "2018-12",
      "has_results": false,
      "last_update_posted_date": "2017-04-04",
      "last_synced_at": "2026-05-22T09:19:05.602Z",
      "location_count": 4,
      "location_summary": "Chicago, Illinois • New York, New York • Ardmore, Pennsylvania + 1 more",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Ardmore",
          "state": "Pennsylvania"
        },
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02600104"
    },
    {
      "nct_id": "NCT06385171",
      "title": "Assessing the Impact of Botulinum Toxin Type A on Facial Wrinkles: A Comprehensive Clinical Investigation",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Wrinkle"
      ],
      "interventions": [
        {
          "name": "Botulinum toxin type A",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Global Aesthetics LLC",
      "sponsor_class": "OTHER",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "20 Years to 65 Years"
      },
      "enrollment_count": 500,
      "start_date": "2024-05-22",
      "completion_date": "2027-01-05",
      "has_results": false,
      "last_update_posted_date": "2024-05-24",
      "last_synced_at": "2026-05-22T09:19:05.602Z",
      "location_count": 2,
      "location_summary": "Cisco, Texas • Lubbock, Texas",
      "locations": [
        {
          "city": "Cisco",
          "state": "Texas"
        },
        {
          "city": "Lubbock",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06385171"
    },
    {
      "nct_id": "NCT05388604",
      "title": "Clinical Study To Evaluate Paired Treatment With An Alexandrite Laser And Radiofrequency Microneedling For Facial Aging",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Wrinkle",
        "Photoaging",
        "Dyschromia"
      ],
      "interventions": [
        {
          "name": "RF device",
          "type": "DEVICE"
        },
        {
          "name": "Microneedling device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Cynosure, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "40 Years to 65 Years"
      },
      "enrollment_count": 42,
      "start_date": "2022-06-15",
      "completion_date": "2023-08-29",
      "has_results": false,
      "last_update_posted_date": "2023-10-18",
      "last_synced_at": "2026-05-22T09:19:05.602Z",
      "location_count": 3,
      "location_summary": "Sacramento, California • Montclair, New Jersey • New York, New York",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Montclair",
          "state": "New Jersey"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05388604"
    },
    {
      "nct_id": "NCT01859611",
      "title": "TriActive+ Radiofrequency (RF) for Non-Invasive Treatment of Wrinkles and Rhytides",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Wrinkles",
        "Rhytides"
      ],
      "interventions": [
        {
          "name": "TriActive+ RF",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "El. En. SpA",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "30 Years to 60 Years"
      },
      "enrollment_count": 51,
      "start_date": "2013-05",
      "completion_date": "2014-05",
      "has_results": true,
      "last_update_posted_date": "2015-04-07",
      "last_synced_at": "2026-05-22T09:19:05.602Z",
      "location_count": 2,
      "location_summary": "Indianapolis, Indiana • New York, New York",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01859611"
    },
    {
      "nct_id": "NCT06629792",
      "title": "A Clinical Study Evaluating the Efficacy and Tolerability of a Topical Facial Treatment For Facial Rejuvenation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Fine Lines",
        "Wrinkles",
        "Laxity; Skin"
      ],
      "interventions": [
        {
          "name": "Gentle Cleanser",
          "type": "OTHER"
        },
        {
          "name": "Facial Moisturizer",
          "type": "OTHER"
        },
        {
          "name": "sunscreen SPF 30",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Revision Skincare",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": "60 Years",
        "sex": "FEMALE",
        "summary": "35 Years to 60 Years · Female only"
      },
      "enrollment_count": 32,
      "start_date": "2022-01-11",
      "completion_date": "2022-05-05",
      "has_results": false,
      "last_update_posted_date": "2024-10-08",
      "last_synced_at": "2026-05-22T09:19:05.602Z",
      "location_count": 1,
      "location_summary": "Richardson, Texas",
      "locations": [
        {
          "city": "Richardson",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06629792"
    },
    {
      "nct_id": "NCT04717934",
      "title": "Main Study: A Study to Evaluate the Effectiveness and Safety of GAL1906 for Correction of Wrinkles in the décolletage Area Sub-study: A Follow-up Study to Evaluate the Analysis of Mammograms Following Treatment for Correction of Wrinkles in Décolletage Area in the Investigational Study 43USRV1906",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Wrinkle"
      ],
      "interventions": [
        {
          "name": "GAL1906",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Galderma R&D",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "22 Years and older · Female only"
      },
      "enrollment_count": 211,
      "start_date": "2025-02-11",
      "completion_date": "2025-06-13",
      "has_results": false,
      "last_update_posted_date": "2025-08-17",
      "last_synced_at": "2026-05-22T09:19:05.602Z",
      "location_count": 14,
      "location_summary": "Birmingham, Alabama • Scottsdale, Arizona • Redondo Beach, California + 11 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "Redondo Beach",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Vista",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04717934"
    },
    {
      "nct_id": "NCT01368900",
      "title": "Reducing Wrinkles Around the Eyes Using the Ulthera® System",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Periorbital Wrinkles"
      ],
      "interventions": [
        {
          "name": "Ulthera® System treatment",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Ulthera, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "30 Years to 65 Years"
      },
      "enrollment_count": 68,
      "start_date": "2011-03",
      "completion_date": "2012-01",
      "has_results": true,
      "last_update_posted_date": "2017-12-13",
      "last_synced_at": "2026-05-22T09:19:05.602Z",
      "location_count": 2,
      "location_summary": "Hunt Valley, Maryland • Nashville, Tennessee",
      "locations": [
        {
          "city": "Hunt Valley",
          "state": "Maryland"
        },
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01368900"
    },
    {
      "nct_id": "NCT01939964",
      "title": "Study to Determine Effectiveness of Activation Mist on Facial Skin Wrinkles",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Skin Wrinkles on Face and Neck Areas"
      ],
      "interventions": [
        {
          "name": "Activation Mist",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "California Allergy and Asthma Medical Group, Inc.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "30 Years to 80 Years"
      },
      "enrollment_count": 60,
      "start_date": "2013-11",
      "completion_date": "2014-08",
      "has_results": false,
      "last_update_posted_date": "2013-09-11",
      "last_synced_at": "2026-05-22T09:19:05.602Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01939964"
    },
    {
      "nct_id": "NCT05096247",
      "title": "Post Market Study To Collect Efficacy Data For The Treatment Of Wrinkles With A Radiofrequency Device",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Wrinkle",
        "Benign Pigmented Lesions",
        "Benign Vascular Lesions"
      ],
      "interventions": [
        {
          "name": "TempSure",
          "type": "DEVICE"
        },
        {
          "name": "Icon",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Cynosure, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 48,
      "start_date": "2021-09-03",
      "completion_date": "2022-09-13",
      "has_results": true,
      "last_update_posted_date": "2023-11-28",
      "last_synced_at": "2026-05-22T09:19:05.602Z",
      "location_count": 3,
      "location_summary": "Westford, Massachusetts • Portsmouth, New Hampshire • Huntersville, North Carolina",
      "locations": [
        {
          "city": "Westford",
          "state": "Massachusetts"
        },
        {
          "city": "Portsmouth",
          "state": "New Hampshire"
        },
        {
          "city": "Huntersville",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05096247"
    },
    {
      "nct_id": "NCT05271136",
      "title": "A Clinical Study to Evaluate the Efficacy of an Anti-Aging Serum",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Fine Lines",
        "Wrinkle",
        "Photoaging"
      ],
      "interventions": [
        {
          "name": "Anti-aging Serum",
          "type": "OTHER"
        },
        {
          "name": "Facial Moisturizer",
          "type": "OTHER"
        },
        {
          "name": "Cleansing Lotion",
          "type": "OTHER"
        },
        {
          "name": "Sunscreen",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Revision Skincare",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "60 Years",
        "sex": "FEMALE",
        "summary": "30 Years to 60 Years · Female only"
      },
      "enrollment_count": 26,
      "start_date": "2020-09-30",
      "completion_date": "2020-10-13",
      "has_results": false,
      "last_update_posted_date": "2022-03-08",
      "last_synced_at": "2026-05-22T09:19:05.602Z",
      "location_count": 1,
      "location_summary": "Richardson, Texas",
      "locations": [
        {
          "city": "Richardson",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05271136"
    }
  ]
}