{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=ctDNA&page=2",
    "query": {
      "condition": "ctDNA",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=ctDNA&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T09:31:25.514Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07401316",
      "title": "Circulating Tumor DNA in Stage I, II, and III Germ-Cell Tumors",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Germ Cell Cancer Metastatic"
      ],
      "interventions": [
        {
          "name": "Whole blood for ctDNA",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Indiana University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 130,
      "start_date": "2026-06-03",
      "completion_date": "2032-12",
      "has_results": false,
      "last_update_posted_date": "2026-06-15",
      "last_synced_at": "2026-07-23T09:31:25.514Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07401316"
    },
    {
      "nct_id": "NCT06207032",
      "title": "TEMPUS ARIES: A Biobank Registry Platform Study in Oncology",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cancer"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Tempus AI",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 500,
      "start_date": "2024-06-26",
      "completion_date": "2029-06-01",
      "has_results": false,
      "last_update_posted_date": "2026-02-24",
      "last_synced_at": "2026-07-23T09:31:25.514Z",
      "location_count": 31,
      "location_summary": "Birmingham, Alabama • Whittier, California • Norwich, Connecticut + 26 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Whittier",
          "state": "California"
        },
        {
          "city": "Norwich",
          "state": "Connecticut"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06207032"
    },
    {
      "nct_id": "NCT04574635",
      "title": "Human Papilloma Virus (HPV) Circulating Tumor DNA (ctDNA) in Cervical Cancer",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cervical Adenosquamous Carcinoma",
        "Cervical Squamous Cell Carcinoma, Not Otherwise Specified",
        "Infiltrating Cervical Carcinoma",
        "Metastatic Cervical Carcinoma",
        "Recurrent Cervical Carcinoma",
        "Stage I Cervical Cancer FIGO 2018",
        "Stage IA Cervical Cancer FIGO 2018",
        "Stage IA1 Cervical Cancer FIGO 2018",
        "Stage IA2 Cervical Cancer FIGO 2018",
        "Stage IB Cervical Cancer FIGO 2018",
        "Stage IB1 Cervical Cancer AJCC v8",
        "Stage IB2 Cervical Cancer FIGO 2018",
        "Stage IB3 Cervical Cancer FIGO 2018",
        "Stage II Cervical Cancer FIGO 2018",
        "Stage IIA Cervical Cancer FIGO 2018",
        "Stage IIA1 Cervical Cancer FIGO 2018",
        "Stage IIA2 Cervical Cancer FIGO 2018",
        "Stage IIB Cervical Cancer FIGO 2018",
        "Stage III Cervical Cancer FIGO 2018",
        "Stage IIIA Cervical Cancer FIGO 2018",
        "Stage IIIB Cervical Cancer FIGO 2018",
        "Stage IIIC Cervical Cancer FIGO 2018",
        "Stage IIIC1 Cervical Cancer FIGO 2018",
        "Stage IIIC2 Cervical Cancer FIGO 2018",
        "Stage IV Cervical Cancer FIGO 2018",
        "Stage IVA Cervical Cancer FIGO 2018",
        "Stage IVB Cervical Cancer FIGO 2018"
      ],
      "interventions": [
        {
          "name": "Biospecimen Collection",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 18,
      "start_date": "2020-11-17",
      "completion_date": "2027-11-30",
      "has_results": false,
      "last_update_posted_date": "2025-10-27",
      "last_synced_at": "2026-07-23T09:31:25.514Z",
      "location_count": 2,
      "location_summary": "Minneapolis, Minnesota • Rochester, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04574635"
    },
    {
      "nct_id": "NCT05730010",
      "title": "Discerning the Impact of ctDNA Detection on Patient Decision Making in Early Stage Breast Cancer: a Conjoint Analysis",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Triple Negative Breast Cancer"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Indiana University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 289,
      "start_date": "2023-04-16",
      "completion_date": "2023-06-26",
      "has_results": false,
      "last_update_posted_date": "2023-08-03",
      "last_synced_at": "2026-07-23T09:31:25.514Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05730010"
    },
    {
      "nct_id": "NCT04510285",
      "title": "A Single-Arm Pilot Study of Adjuvant Pembrolizumab Plus Trastuzumab in HER2+ Esophagogastric Tumors With Persistent Circulating Tumor DNA Following Curative Resection",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Esophagogastric Tumors",
        "Gastric Cancer",
        "Gastric Tumor",
        "Esophageal Cancer",
        "Esophageal Neoplasms",
        "Esophageal Tumor",
        "GastroEsophageal Cancer",
        "Gastroesophageal Junction Adenocarcinoma",
        "Gastroesophageal Junction Tumor",
        "Gastroesophageal Junction Cancer"
      ],
      "interventions": [
        {
          "name": "Trastuzumab",
          "type": "DRUG"
        },
        {
          "name": "Pembrolizumab",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Memorial Sloan Kettering Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1,
      "start_date": "2020-08-10",
      "completion_date": "2022-12-30",
      "has_results": true,
      "last_update_posted_date": "2023-02-01",
      "last_synced_at": "2026-07-23T09:31:25.514Z",
      "location_count": 7,
      "location_summary": "Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more",
      "locations": [
        {
          "city": "Basking Ridge",
          "state": "New Jersey"
        },
        {
          "city": "Middletown",
          "state": "New Jersey"
        },
        {
          "city": "Montvale",
          "state": "New Jersey"
        },
        {
          "city": "Commack",
          "state": "New York"
        },
        {
          "city": "Harrison",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04510285"
    },
    {
      "nct_id": "NCT04929015",
      "title": "Peritoneal Carcinomatosis Leveraging ctDNA Guided Treatment in GI Cancer Study (PERICLES Study)",
      "overall_status": "SUSPENDED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Appendix Carcinoma by AJCC V8 Stage",
        "Colorectal Carcinoma by AJCC V8 Stage",
        "Digestive System Neoplasm",
        "Esophageal Carcinoma by AJCC V8 Stage",
        "Gastric Carcinoma by AJCC V8 Stage",
        "Liver and Intrahepatic Bile Duct Carcinoma",
        "Peritoneal Carcinomatosis"
      ],
      "interventions": [
        {
          "name": "Biospecimen Collection - blood and tissue sample collection",
          "type": "PROCEDURE"
        },
        {
          "name": "Electronic Health Record Review",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "OTHER"
      ],
      "sponsor": "Rutgers, The State University of New Jersey",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2021-04-29",
      "completion_date": "2027-09-01",
      "has_results": false,
      "last_update_posted_date": "2026-05-04",
      "last_synced_at": "2026-07-23T09:31:25.514Z",
      "location_count": 2,
      "location_summary": "Livingston, New Jersey • New Brunswick, New Jersey",
      "locations": [
        {
          "city": "Livingston",
          "state": "New Jersey"
        },
        {
          "city": "New Brunswick",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04929015"
    },
    {
      "nct_id": "NCT03553550",
      "title": "Role of Circulating Tumor DNA (ctDNA) From LIquid Biopsy in Early Stage NSCLC Resected Lung Tumor Investigation",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Non Small Cell Lung Cancer"
      ],
      "interventions": [
        {
          "name": "biospecimen collection",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Addario Lung Cancer Medical Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 38,
      "start_date": "2018-06-01",
      "completion_date": "2020-11-15",
      "has_results": false,
      "last_update_posted_date": "2020-11-19",
      "last_synced_at": "2026-07-23T09:31:25.514Z",
      "location_count": 6,
      "location_summary": "Atlanta, Georgia • Chicago, Illinois • Boston, Massachusetts + 3 more",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Bridgeton",
          "state": "Missouri"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03553550"
    },
    {
      "nct_id": "NCT04786600",
      "title": "A Phase II Randomized Therapeutic Optimization Trial for Subjects With Refractory Metastatic Colorectal Cancer Using ctDNA: Rapid 1 Trial",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Metastatic Colorectal Cancer"
      ],
      "interventions": [
        {
          "name": "Signatera ctDNA assay",
          "type": "DEVICE"
        },
        {
          "name": "pre-specified sequence of FDA-approved drugs and drug combinations",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 6,
      "start_date": "2022-03-14",
      "completion_date": "2024-03-19",
      "has_results": true,
      "last_update_posted_date": "2025-07-01",
      "last_synced_at": "2026-07-23T09:31:25.514Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04786600"
    },
    {
      "nct_id": "NCT03161834",
      "title": "Plasma Circulating Tumor DNA Analyses in ER+ Metastatic Breast Cancer",
      "overall_status": "WITHDRAWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Metastatic Breast Cancer"
      ],
      "interventions": [
        {
          "name": "Observational",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "UNC Lineberger Comprehensive Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 99 Years · Female only"
      },
      "enrollment_count": 0,
      "start_date": "2017-01-13",
      "completion_date": "2020-07-09",
      "has_results": false,
      "last_update_posted_date": "2021-05-21",
      "last_synced_at": "2026-07-23T09:31:25.514Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03161834"
    },
    {
      "nct_id": "NCT04920344",
      "title": "Swallowing Outcomes and Circulating Tumor DNA in Patients With HPV Related Oropharyngeal Cancer Treated With Transoral Surgery and Reduced Intensity Adjuvant Therapy",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8",
        "Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8",
        "Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8",
        "Oropharyngeal Human Papillomavirus-Positive Squamous Cell Carcinoma"
      ],
      "interventions": [
        {
          "name": "Transoral Surgery",
          "type": "PROCEDURE"
        },
        {
          "name": "External Beam Radiation Therapy",
          "type": "RADIATION"
        },
        {
          "name": "Cisplatin",
          "type": "DRUG"
        },
        {
          "name": "Incisional Tumor Biopsy",
          "type": "PROCEDURE"
        },
        {
          "name": "Circulating tumor deoxyribonucleic acid (ctDNA) levels assessment",
          "type": "OTHER"
        },
        {
          "name": "MD Anderson Dysphagia Index",
          "type": "OTHER"
        },
        {
          "name": "University of Washington Quality of Life Questionnaire",
          "type": "OTHER"
        },
        {
          "name": "Euro-QOL 5 dimension scale questionnaire",
          "type": "OTHER"
        },
        {
          "name": "Modified barium swallow (MBS) evaluation with aspiration-penetration scale",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "RADIATION",
        "DRUG",
        "OTHER",
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Rutgers, The State University of New Jersey",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 15,
      "start_date": "2021-07-19",
      "completion_date": "2025-05-08",
      "has_results": false,
      "last_update_posted_date": "2023-11-03",
      "last_synced_at": "2026-07-23T09:31:25.514Z",
      "location_count": 3,
      "location_summary": "New Brunswick, New Jersey • Newark, New Jersey",
      "locations": [
        {
          "city": "New Brunswick",
          "state": "New Jersey"
        },
        {
          "city": "New Brunswick",
          "state": "New Jersey"
        },
        {
          "city": "Newark",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04920344"
    }
  ]
}