{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=de+Novo+Coronary+Lesions",
    "query": {
      "condition": "de Novo Coronary Lesions"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 45,
    "total_pages": 5,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=de+Novo+Coronary+Lesions&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-24T09:36:43.962Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00371748",
      "title": "A Study of the TAXUS Liberté Stent for the Treatment of de Novo Coronary Artery Lesions in Small Vessels",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Coronary Artery Disease"
      ],
      "interventions": [
        {
          "name": "TAXUS Liberté-SR",
          "type": "DEVICE"
        },
        {
          "name": "TAXUS™ Express2",
          "type": "DEVICE"
        },
        {
          "name": "Express2",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Boston Scientific Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 261,
      "start_date": "2005-02",
      "completion_date": "2011-04",
      "has_results": false,
      "last_update_posted_date": "2012-02-02",
      "last_synced_at": "2026-07-24T09:36:43.962Z",
      "location_count": 19,
      "location_summary": "Sacramento, California • Newark, Delaware • Orlando, Florida + 16 more",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Newark",
          "state": "Delaware"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Springfield",
          "state": "Illinois"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00371748"
    },
    {
      "nct_id": "NCT00180479",
      "title": "SPIRIT III Clinical Trial of the XIENCE V® Everolimus Eluting Coronary Stent System (EECSS)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Stents",
        "Coronary Artery Disease",
        "Total Coronary Occlusion",
        "Coronary Artery Restenosis",
        "Stent Thrombosis",
        "Vascular Disease",
        "Myocardial Ischemia",
        "Coronary Artery Stenosis"
      ],
      "interventions": [
        {
          "name": "XIENCE V® Everolimus Eluting Coronary Stent",
          "type": "DEVICE"
        },
        {
          "name": "TAXUS® EXPRESS2™ Paclitaxel Eluting Coronary Stent",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Abbott Medical Devices",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1002,
      "start_date": "2005-06",
      "completion_date": "2011-11",
      "has_results": true,
      "last_update_posted_date": "2011-11-23",
      "last_synced_at": "2026-07-24T09:36:43.962Z",
      "location_count": 65,
      "location_summary": "Birmingham, Alabama • Phoenix, Arizona • La Jolla, California + 56 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00180479"
    },
    {
      "nct_id": "NCT00489541",
      "title": "TAXUS PERSEUS Small Vessel",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Coronary Artery Disease"
      ],
      "interventions": [
        {
          "name": "Percutaneous Coronary Intervention (PCI) with paclitaxel-eluting stent (TAXUS Element) implantation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Boston Scientific Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 224,
      "start_date": "2007-07",
      "completion_date": "2013-10",
      "has_results": true,
      "last_update_posted_date": "2014-05-08",
      "last_synced_at": "2026-07-24T09:36:43.962Z",
      "location_count": 28,
      "location_summary": "Birmingham, Alabama • Bakersfield, California • La Jolla, California + 24 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Bakersfield",
          "state": "California"
        },
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "Newark",
          "state": "Delaware"
        },
        {
          "city": "Ocala",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00489541"
    },
    {
      "nct_id": "NCT00231283",
      "title": "NEXUS Study for the Treatment of de Novo Native Coronary Artery Lesions",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Coronary Artery Disease"
      ],
      "interventions": [
        {
          "name": "CYPHER NxT SES ON BX SONIC OTW STENT DELIVERY SYSTEM (SDS)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Cordis US Corp.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2004-04",
      "completion_date": "2005-07",
      "has_results": true,
      "last_update_posted_date": "2010-04-20",
      "last_synced_at": "2026-07-24T09:36:43.962Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00231283"
    },
    {
      "nct_id": "NCT02389946",
      "title": "Safety and Effectiveness of the Orsiro Sirolimus Eluting Coronary Stent System in Subjects With Coronary Artery Lesions",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Coronary Artery Disease",
        "Atherosclerosis, Coronary",
        "Myocardial Ischemia",
        "Ischemic Heart Disease",
        "Acute Coronary Syndrome",
        "Angina Pectoris"
      ],
      "interventions": [
        {
          "name": "Orsiro DES",
          "type": "DEVICE"
        },
        {
          "name": "Xience DES",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Biotronik, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1334,
      "start_date": "2015-05",
      "completion_date": "2021-03",
      "has_results": true,
      "last_update_posted_date": "2022-08-03",
      "last_synced_at": "2026-07-24T09:36:43.962Z",
      "location_count": 55,
      "location_summary": "Fairhope, Alabama • Concord, California • La Mesa, California + 49 more",
      "locations": [
        {
          "city": "Fairhope",
          "state": "Alabama"
        },
        {
          "city": "Concord",
          "state": "California"
        },
        {
          "city": "La Mesa",
          "state": "California"
        },
        {
          "city": "Laguna Hills",
          "state": "California"
        },
        {
          "city": "Mission Viejo",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02389946"
    },
    {
      "nct_id": "NCT00569751",
      "title": "TAXUS ARRIVE 2: A Multi-Center Safety Surveillance Program",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Cardiovascular Disease",
        "de Novo Coronary Lesions"
      ],
      "interventions": [
        {
          "name": "TAXUS™ Express2™ Paclitaxel-Eluting Coronary Stent System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Boston Scientific Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 5016,
      "start_date": "2004-10",
      "completion_date": "2008-07",
      "has_results": false,
      "last_update_posted_date": "2008-09-29",
      "last_synced_at": "2026-07-24T09:36:43.962Z",
      "location_count": 53,
      "location_summary": "Scottsdale, Arizona • Bakersfield, California • Rancho Mirage, California + 49 more",
      "locations": [
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "Bakersfield",
          "state": "California"
        },
        {
          "city": "Rancho Mirage",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00569751"
    },
    {
      "nct_id": "NCT05946629",
      "title": "SELUTION 4 De Novo Small Vessel IDE Trial",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Coronary Artery Disease"
      ],
      "interventions": [
        {
          "name": "PCI with SELUTION SLR DCB",
          "type": "DEVICE"
        },
        {
          "name": "PCI with FDA approved \"-limus\" DES",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "M.A. Med Alliance S.A.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 960,
      "start_date": "2023-10-20",
      "completion_date": "2031-06",
      "has_results": false,
      "last_update_posted_date": "2026-07-16",
      "last_synced_at": "2026-07-24T09:36:43.962Z",
      "location_count": 66,
      "location_summary": "Jonesboro, Arkansas • Chula Vista, California • Los Angeles, California + 55 more",
      "locations": [
        {
          "city": "Jonesboro",
          "state": "Arkansas"
        },
        {
          "city": "Chula Vista",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Thousand Oaks",
          "state": "California"
        },
        {
          "city": "Torrance",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05946629"
    },
    {
      "nct_id": "NCT07258290",
      "title": "Safety and Clinical Performance of the Freesolve Resorbable Magnesium Scaffold (RMS) System in Subjects With Coronary Artery Lesions",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Coronary Disease",
        "Heart Diseases",
        "Cardiovascular Diseases",
        "Arteriosclerosis",
        "Arterial Occlusive Diseases",
        "Vascular Diseases",
        "Chest Pain",
        "Pain",
        "Neurologic Manifestations",
        "Signs and Symptoms",
        "Pathological Conditions, Signs and Symptoms",
        "Coronary Artery Disease",
        "Myocardial Ischemia",
        "Acute Coronary Syndrome",
        "Angina Pectoris"
      ],
      "interventions": [
        {
          "name": "Freesolve RMS",
          "type": "DEVICE"
        },
        {
          "name": "Xience DES",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Teleflex",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 1859,
      "start_date": "2026-06-11",
      "completion_date": "2033-06",
      "has_results": false,
      "last_update_posted_date": "2026-06-17",
      "last_synced_at": "2026-07-24T09:36:43.962Z",
      "location_count": 1,
      "location_summary": "Washington D.C., District of Columbia",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07258290"
    },
    {
      "nct_id": "NCT02173379",
      "title": "Absorb IV Randomized Controlled Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Coronary Artery Disease",
        "Coronary Artery Stenosis",
        "Coronary Disease",
        "Coronary Stenosis"
      ],
      "interventions": [
        {
          "name": "Absorb BVS",
          "type": "DEVICE"
        },
        {
          "name": "XIENCE",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Abbott Medical Devices",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2604,
      "start_date": "2014-07",
      "completion_date": "2022-04-06",
      "has_results": true,
      "last_update_posted_date": "2023-10-30",
      "last_synced_at": "2026-07-24T09:36:43.962Z",
      "location_count": 98,
      "location_summary": "Birmingham, Alabama • Chandler, Arizona • Gilbert, Arizona + 82 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Chandler",
          "state": "Arizona"
        },
        {
          "city": "Gilbert",
          "state": "Arizona"
        },
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02173379"
    },
    {
      "nct_id": "NCT00307047",
      "title": "SPIRIT IV Clinical Trial: Clinical Evaluation of the XIENCE V® Everolimus Eluting Coronary Stent System",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Coronary Artery Disease"
      ],
      "interventions": [
        {
          "name": "XIENCE V® Everolimus Eluting Coronary Stent",
          "type": "DEVICE"
        },
        {
          "name": "TAXUS™ EXPRESS2™ Paclitaxel Eluting Coronary Stent",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Abbott Medical Devices",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 3687,
      "start_date": "2006-08",
      "completion_date": "2012-05",
      "has_results": true,
      "last_update_posted_date": "2012-11-07",
      "last_synced_at": "2026-07-24T09:36:43.962Z",
      "location_count": 65,
      "location_summary": "Scottsdale, Arizona • Little Rock, Arkansas • Fairfax, California + 54 more",
      "locations": [
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Fairfax",
          "state": "California"
        },
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "La Jolla",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00307047"
    }
  ]
}