{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=0.12%25+chlorhexidine+mouthrinse", "query": { "intervention": "0.12% chlorhexidine mouthrinse" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 5, "total_pages": 1, "next_page_url": null, "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-10-03T22:55:06.968Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT01568944", "title": "Role of Infected Blood Dendritic Cells in Heart Disease Risk", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Chronic Periodontitis" ], "interventions": [ { "name": "Oral Antibiotic and Oral Rinse", "type": "DRUG" }, { "name": "Standard Treatment", "type": "PROCEDURE" } ], "intervention_types": [ "DRUG", "PROCEDURE" ], "sponsor": "Augusta University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "40 Years", "maximum_age": null, "sex": "ALL", "summary": "40 Years and older" }, "enrollment_count": 18, "start_date": "2012-03", "completion_date": "2014-09", "has_results": true, "last_update_posted_date": "2020-05-12", "last_synced_at": "2026-10-03T22:55:06.968Z", "location_count": 1, "location_summary": "Augusta, Georgia", "locations": [ { "city": "Augusta", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT01568944" }, { "nct_id": "NCT02709785", "title": "SmartMouth Advanced Clinical Formula Clinical Research Design Protocol", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Gingivitis", "Periodontitis" ], "interventions": [ { "name": "SmartMouth Clinical DDS mouthrinse", "type": "DRUG" }, { "name": "0.12% chlorhexidine rinse", "type": "DRUG" }, { "name": "Placebo rinse", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "St. Louis University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 80, "start_date": "2016-03", "completion_date": "2017-05", "has_results": true, "last_update_posted_date": "2018-12-04", "last_synced_at": "2026-10-03T22:55:06.968Z", "location_count": 2, "location_summary": "Alton, Illinois • St Louis, Missouri", "locations": [ { "city": "Alton", "state": "Illinois" }, { "city": "St Louis", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT02709785" }, { "nct_id": "NCT07191262", "title": "To Compare Post-Extraction Use of a Novel Ethylenediaminetetraacetic Acid (EDTA) Post-operative Mouth Rinse and Daily Use EDTA Mouth Rinse and Standard 0.12% Chlorhexidine (CHX) Post-operative Mouth Rinse and Daily Use Essential Oil (EO) Mouth Rinse.", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Extraction Sites After Removal and Bone Replacement Grafting at Extraction Sockets of Dentally Hopeless Single-rooted Teeth" ], "interventions": [ { "name": "0.12% CHX and Essential Oil mouthrinse", "type": "OTHER" }, { "name": "2.6% EDTA and 0.2% EDTA mouth rinse", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "University of Alabama at Birmingham", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "18 Years to 85 Years" }, "enrollment_count": 40, "start_date": "2026-03-02", "completion_date": "2028-12", "has_results": false, "last_update_posted_date": "2026-03-20", "last_synced_at": "2026-10-03T22:55:06.968Z", "location_count": 1, "location_summary": "Birmingham, Alabama", "locations": [ { "city": "Birmingham", "state": "Alabama" } ], "official_url": "https://clinicaltrials.gov/study/NCT07191262" }, { "nct_id": "NCT02598778", "title": "Comparing Mouth Rinses (and Chewing Gum) in Regard to Streptococcus Mutans Reduction", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Dental Caries" ], "interventions": [ { "name": "Chlorhexidine gluconate (0.12%)", "type": "DRUG" }, { "name": "Sodium Fluoride (0.05%)", "type": "DRUG" }, { "name": "Paraffin wax chewing gum (sugar-free)", "type": "OTHER" }, { "name": "Deionized water", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Montefiore Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "6 Years", "maximum_age": "12 Years", "sex": "ALL", "summary": "6 Years to 12 Years" }, "enrollment_count": 12, "start_date": "2015-11-01", "completion_date": "2016-04-01", "has_results": true, "last_update_posted_date": "2022-10-31", "last_synced_at": "2026-10-03T22:55:06.968Z", "location_count": 1, "location_summary": "The Bronx, New York", "locations": [ { "city": "The Bronx", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT02598778" }, { "nct_id": "NCT01122862", "title": "Effect of a Commercial Cosmetic Mouth Rinse on Plaque Re-growth", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Healthy Subjects" ], "interventions": [ { "name": "0.12% chlorhexidine mouthrinse", "type": "DRUG" }, { "name": "Cosmetic mouthrinse", "type": "OTHER" }, { "name": "Sterile water", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "GlaxoSmithKline", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 23, "start_date": "2010-04", "completion_date": "2010-05", "has_results": true, "last_update_posted_date": "2013-09-09", "last_synced_at": "2026-10-03T22:55:06.968Z", "location_count": 1, "location_summary": "Fort Wayne, Indiana", "locations": [ { "city": "Fort Wayne", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT01122862" } ] }