{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=0.125%25+Marcaine",
    "query": {
      "intervention": "0.125% Marcaine"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 40,
    "total_pages": 4,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=0.125%25+Marcaine&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-26T19:43:17.693Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01243112",
      "title": "Effectiveness Study of Different Local Anesthetic Mixtures",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Pain"
      ],
      "interventions": [
        {
          "name": "1% Lidocaine with Epinephrine (1:100,000)",
          "type": "DRUG"
        },
        {
          "name": "0.25% Bupivacaine with Epinephrine (1:200,000)",
          "type": "DRUG"
        },
        {
          "name": "0.5% Lidocaine, 0.125 Bupivacaine, and epi (1:150,000)",
          "type": "DRUG"
        },
        {
          "name": "1% Lidocaine, 0.5% Bupivacaine, and epinephrine (1:150,000)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Scott and White Hospital & Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 25,
      "start_date": "2010-05",
      "completion_date": "2010-09",
      "has_results": true,
      "last_update_posted_date": "2011-12-02",
      "last_synced_at": "2026-09-26T19:43:17.693Z",
      "location_count": 1,
      "location_summary": "Temple, Texas",
      "locations": [
        {
          "city": "Temple",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01243112"
    },
    {
      "nct_id": "NCT06995352",
      "title": "Liposomal Bupivacaine Versus Continuous Peripheral Nerve Blocks for Analgesia Following Ankle Surgery",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Moderate-to-severely Painful Ankle Surgery"
      ],
      "interventions": [
        {
          "name": "Popliteal nerve block including liposomal bupivacaine",
          "type": "DRUG"
        },
        {
          "name": "Adductor canal nerve block including liposomal bupivacaine",
          "type": "DRUG"
        },
        {
          "name": "Continuous popliteal nerve block with normal saline",
          "type": "DRUG"
        },
        {
          "name": "Popliteal nerve block with exclusively unencapsulated bupivacaine",
          "type": "DRUG"
        },
        {
          "name": "Adductor canal nerve block with exclusively unencapsulated bupivacaine",
          "type": "DRUG"
        },
        {
          "name": "Continuous popliteal nerve block with unencapsulated bupivacaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, San Diego",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 140,
      "start_date": "2025-06-23",
      "completion_date": "2027-06-22",
      "has_results": false,
      "last_update_posted_date": "2026-09-16",
      "last_synced_at": "2026-09-26T19:43:17.693Z",
      "location_count": 1,
      "location_summary": "La Jolla, California",
      "locations": [
        {
          "city": "La Jolla",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06995352"
    },
    {
      "nct_id": "NCT02681796",
      "title": "Epidural Analgesia Use in Pancreatic Resections",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Cancer of Pancreas",
        "Cancer of the Pancreas",
        "Pancreas Cancer",
        "Pancreas Neoplasms",
        "Pancreatic Cancer"
      ],
      "interventions": [
        {
          "name": "Bupivacaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 23,
      "start_date": "2016-06-07",
      "completion_date": "2020-02-07",
      "has_results": false,
      "last_update_posted_date": "2020-03-12",
      "last_synced_at": "2026-09-26T19:43:17.693Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02681796"
    },
    {
      "nct_id": "NCT02008591",
      "title": "Comparison of Epidural Labor Pain Relief Techniques on Maternal and Fetal Outcomes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Laboring Women Requesting Neuraxial Labor Analgesia"
      ],
      "interventions": [
        {
          "name": "Epidural Technique versus Dural Puncture Epidural Technique versus Combined Spinal Epidural Technique",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 50 Years · Female only"
      },
      "enrollment_count": 120,
      "start_date": "2013-11-26",
      "completion_date": "2016-01-27",
      "has_results": false,
      "last_update_posted_date": "2017-01-24",
      "last_synced_at": "2026-09-26T19:43:17.693Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02008591"
    },
    {
      "nct_id": "NCT01566838",
      "title": "Continuous Subpleural Infusion of Bupivacaine",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Postoperative Pain"
      ],
      "interventions": [
        {
          "name": "Subpleural pain catheter with infusion of 0.125% bupivacaine",
          "type": "DRUG"
        },
        {
          "name": "Standard acute pain management",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Inova Health Care Services",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 83,
      "start_date": "2012-10",
      "completion_date": "2015-12",
      "has_results": true,
      "last_update_posted_date": "2017-12-20",
      "last_synced_at": "2026-09-26T19:43:17.693Z",
      "location_count": 1,
      "location_summary": "Falls Church, Virginia",
      "locations": [
        {
          "city": "Falls Church",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01566838"
    },
    {
      "nct_id": "NCT04585867",
      "title": "Liposomal Bupivacaine vs Bupivacaine for Pain Control After Sternotomy",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Pain Management",
        "Sternotomy"
      ],
      "interventions": [
        {
          "name": "Exparel",
          "type": "DRUG"
        },
        {
          "name": "Bupivacaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Kansas Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 80,
      "start_date": "2017-10-11",
      "completion_date": "2023-10-10",
      "has_results": false,
      "last_update_posted_date": "2020-10-14",
      "last_synced_at": "2026-09-26T19:43:17.693Z",
      "location_count": 1,
      "location_summary": "Kansas City, Kansas",
      "locations": [
        {
          "city": "Kansas City",
          "state": "Kansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04585867"
    },
    {
      "nct_id": "NCT02472314",
      "title": "Exparel for Postoperative Pain Management in Shoulder Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Fracture of Shoulder and Upper Arm"
      ],
      "interventions": [
        {
          "name": "1.3% Liposomal Bupivacaine",
          "type": "DRUG"
        },
        {
          "name": "0.125% Bupivacaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Wayne State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 70,
      "start_date": "2015-06",
      "completion_date": "2017-05",
      "has_results": true,
      "last_update_posted_date": "2023-12-29",
      "last_synced_at": "2026-09-26T19:43:17.693Z",
      "location_count": 1,
      "location_summary": "Dearborn, Michigan",
      "locations": [
        {
          "city": "Dearborn",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02472314"
    },
    {
      "nct_id": "NCT03702621",
      "title": "Comparing Liposomal Bupivacaine Versus Standard Bupivacaine in Colorectal Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Colorectal Surgery"
      ],
      "interventions": [
        {
          "name": "liposomal Bupivacaine",
          "type": "DRUG"
        },
        {
          "name": "Bupivacaine Hydrochloride",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Indiana University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 90,
      "start_date": "2018-08-30",
      "completion_date": "2020-03-13",
      "has_results": true,
      "last_update_posted_date": "2023-05-17",
      "last_synced_at": "2026-09-26T19:43:17.693Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03702621"
    },
    {
      "nct_id": "NCT04300231",
      "title": "Thoracic Epidural Analgesia Versus Rectus Sheath Block Versus Surgeon Infiltration With Liposomal Bupivacaine or Standard Bupivacaine for Post-Operative Pain Control After Cystectomy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Cystectomy"
      ],
      "interventions": [
        {
          "name": "epidural bupivacaine 0.05%",
          "type": "DRUG"
        },
        {
          "name": "Liposomal bupivacaine",
          "type": "DRUG"
        },
        {
          "name": "bupivacaine 0.125%",
          "type": "DRUG"
        },
        {
          "name": "bupivacaine 0.5%",
          "type": "DRUG"
        },
        {
          "name": "/hydromorphone 0.05mg/ml",
          "type": "DRUG"
        },
        {
          "name": "injectable saline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Indiana University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 160,
      "start_date": "2019-10-22",
      "completion_date": "2021-12-24",
      "has_results": true,
      "last_update_posted_date": "2025-02-10",
      "last_synced_at": "2026-09-26T19:43:17.693Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04300231"
    },
    {
      "nct_id": "NCT02121392",
      "title": "Epidural Catheter With or Without Adductor Canal Nerve Block for Postoperative Analgesia Following Total Knee Arthroplasty",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Arthroplasty, Replacement, Knee",
        "Nerve Block"
      ],
      "interventions": [
        {
          "name": "Adductor Canal Nerve Block Catheter",
          "type": "DEVICE"
        },
        {
          "name": "Adductor Canal Nerve Block Sham Catheter",
          "type": "DEVICE"
        },
        {
          "name": "Bupivacaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "University of Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "Up to 85 Years"
      },
      "enrollment_count": 165,
      "start_date": "2014-10",
      "completion_date": "2017-01",
      "has_results": true,
      "last_update_posted_date": "2020-10-20",
      "last_synced_at": "2026-09-26T19:43:17.693Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02121392"
    }
  ]
}