{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=0.125%25+Marcaine&page=2",
    "query": {
      "intervention": "0.125% Marcaine",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 40,
    "total_pages": 4,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=0.125%25+Marcaine&page=3&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=0.125%25+Marcaine&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-07T23:24:42.831Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03574376",
      "title": "Liposomal Bupivacaine Intercostal Nerve Block vs Thoracic Epidural for Regional Analgesia in Multiple Rib Fractures",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Trauma",
        "Trauma Injury",
        "Pain, Acute"
      ],
      "interventions": [
        {
          "name": "Bupivacaine Liposome Injection",
          "type": "DRUG"
        },
        {
          "name": "Bupivacaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Chadrick Evans",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 258,
      "start_date": "2018-08-29",
      "completion_date": "2021-08-01",
      "has_results": false,
      "last_update_posted_date": "2020-03-09",
      "last_synced_at": "2026-10-07T23:24:42.831Z",
      "location_count": 1,
      "location_summary": "Peoria, Illinois",
      "locations": [
        {
          "city": "Peoria",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03574376"
    },
    {
      "nct_id": "NCT01429584",
      "title": "The Effect of Interscalene Peripheral Nerve Block With 0.25% Bupivacaine vs 0.125% Bupivacaine on Lung Function",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diaphragm Paralysis"
      ],
      "interventions": [
        {
          "name": "interscalene nerve block with 0.25% bupivacaine",
          "type": "DRUG"
        },
        {
          "name": "interscalene block with 0.125% bupivacaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2008-05",
      "completion_date": "2010-02",
      "has_results": true,
      "last_update_posted_date": "2013-12-19",
      "last_synced_at": "2026-10-07T23:24:42.831Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01429584"
    },
    {
      "nct_id": "NCT06995352",
      "title": "Liposomal Bupivacaine Versus Continuous Peripheral Nerve Blocks for Analgesia Following Ankle Surgery",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Moderate-to-severely Painful Ankle Surgery"
      ],
      "interventions": [
        {
          "name": "Popliteal nerve block including liposomal bupivacaine",
          "type": "DRUG"
        },
        {
          "name": "Adductor canal nerve block including liposomal bupivacaine",
          "type": "DRUG"
        },
        {
          "name": "Continuous popliteal nerve block with normal saline",
          "type": "DRUG"
        },
        {
          "name": "Popliteal nerve block with exclusively unencapsulated bupivacaine",
          "type": "DRUG"
        },
        {
          "name": "Adductor canal nerve block with exclusively unencapsulated bupivacaine",
          "type": "DRUG"
        },
        {
          "name": "Continuous popliteal nerve block with unencapsulated bupivacaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, San Diego",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 140,
      "start_date": "2025-06-23",
      "completion_date": "2027-06-22",
      "has_results": false,
      "last_update_posted_date": "2026-09-16",
      "last_synced_at": "2026-10-07T23:24:42.831Z",
      "location_count": 1,
      "location_summary": "La Jolla, California",
      "locations": [
        {
          "city": "La Jolla",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06995352"
    },
    {
      "nct_id": "NCT02178553",
      "title": "Study of Exparel Versus Epidural for Pain Control After Thoracotomy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Pain Following Thoracotomy Surgery"
      ],
      "interventions": [
        {
          "name": "Epidural",
          "type": "DRUG"
        },
        {
          "name": "Intercostal Bupivicaine (Exparel)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 102,
      "start_date": "2014-10-15",
      "completion_date": "2019-01-25",
      "has_results": true,
      "last_update_posted_date": "2020-01-09",
      "last_synced_at": "2026-10-07T23:24:42.831Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02178553"
    },
    {
      "nct_id": "NCT02192879",
      "title": "TEA vs. PVB vs. PCA in Liver Resection Surgery",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pain Management Strategies in Liver Resection Surgery"
      ],
      "interventions": [
        {
          "name": "thoracic epidural",
          "type": "DEVICE"
        },
        {
          "name": "continuous paravertebral catheter",
          "type": "DEVICE"
        },
        {
          "name": "Patient-Controlled Analgesia",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 10,
      "start_date": "2014-08",
      "completion_date": "2016-05",
      "has_results": true,
      "last_update_posted_date": "2016-10-24",
      "last_synced_at": "2026-10-07T23:24:42.831Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02192879"
    },
    {
      "nct_id": "NCT01982838",
      "title": "Effects of Analgesic Techniques on Duration of Spontaneously Laboring Patients",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Effects of; Anesthesia, in Labor and Delivery",
        "Pregnancy",
        "Prolonged First Stage of Labor"
      ],
      "interventions": [
        {
          "name": "Epidural de novo",
          "type": "PROCEDURE"
        },
        {
          "name": "CSE",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Northwestern University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 129,
      "start_date": "2010-07",
      "completion_date": "2014-03",
      "has_results": false,
      "last_update_posted_date": "2014-03-11",
      "last_synced_at": "2026-10-07T23:24:42.831Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01982838"
    },
    {
      "nct_id": "NCT04003987",
      "title": "ESP Block VS TAP in Laparoscopic Hysterectomy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Hysterectomy"
      ],
      "interventions": [
        {
          "name": "Liposomal bupivacaine",
          "type": "DRUG"
        },
        {
          "name": "bupivacaine, 0.125%",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Indiana University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 78,
      "start_date": "2019-05-01",
      "completion_date": "2021-03-04",
      "has_results": true,
      "last_update_posted_date": "2022-07-05",
      "last_synced_at": "2026-10-07T23:24:42.831Z",
      "location_count": 2,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04003987"
    },
    {
      "nct_id": "NCT00600158",
      "title": "Effects of Intravenous Local Anesthetic on Bowel Function After Colectomy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Postoperative Ileus"
      ],
      "interventions": [
        {
          "name": "bupivacaine with hydromorphone",
          "type": "DRUG"
        },
        {
          "name": "lidocaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Virginia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 45,
      "start_date": "2005-04",
      "completion_date": "2006-07",
      "has_results": false,
      "last_update_posted_date": "2008-01-24",
      "last_synced_at": "2026-10-07T23:24:42.831Z",
      "location_count": 1,
      "location_summary": "Charlottesville, Virginia",
      "locations": [
        {
          "city": "Charlottesville",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00600158"
    },
    {
      "nct_id": "NCT04033562",
      "title": "The Analgesic Efficacy of Continuous Sub-fascial Bupivacaine Infusion and Lidocaine Patches in Post-cesarean Patients With Opiate Use Disorder: A Comparative Efficacy Analysis",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Opioid-use Disorder",
        "Opioid Use",
        "Opioid Dependence",
        "Opioid Abuse",
        "Medication Assisted Treatment",
        "Infusion Catheter, Wound",
        "Lidopatch",
        "Ambu ACTion",
        "Pregnancy Related",
        "Cesarean Section"
      ],
      "interventions": [
        {
          "name": "Lidocaine patch",
          "type": "DRUG"
        },
        {
          "name": "Ambu ACTion pump, 0.125% bupivacaine at 8cc/hr",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "WellSpan Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 100 Years · Female only"
      },
      "enrollment_count": 2,
      "start_date": "2020-01-15",
      "completion_date": "2021-05-17",
      "has_results": false,
      "last_update_posted_date": "2021-06-07",
      "last_synced_at": "2026-10-07T23:24:42.831Z",
      "location_count": 1,
      "location_summary": "York, Pennsylvania",
      "locations": [
        {
          "city": "York",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04033562"
    },
    {
      "nct_id": "NCT02008591",
      "title": "Comparison of Epidural Labor Pain Relief Techniques on Maternal and Fetal Outcomes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Laboring Women Requesting Neuraxial Labor Analgesia"
      ],
      "interventions": [
        {
          "name": "Epidural Technique versus Dural Puncture Epidural Technique versus Combined Spinal Epidural Technique",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 50 Years · Female only"
      },
      "enrollment_count": 120,
      "start_date": "2013-11-26",
      "completion_date": "2016-01-27",
      "has_results": false,
      "last_update_posted_date": "2017-01-24",
      "last_synced_at": "2026-10-07T23:24:42.831Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02008591"
    }
  ]
}