{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=0.45+Normal+Saline", "query": { "intervention": "0.45 Normal Saline" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 22, "total_pages": 3, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=0.45+Normal+Saline&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-09T08:04:43.859Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT02876796", "title": "Study to Evaluate the Pharmacodynamic Effects of a Single Oral Dose of GS-0976 (NDI-010976) in Healthy Adult Subjects", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "PD Effects of GS-0976 (NDI-010976) on Fractional DNL" ], "interventions": [ { "name": "GS-0976", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "1-13C acetate", "type": "OTHER" }, { "name": "Fructose solution", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Gilead Sciences", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "50 Years", "sex": "MALE", "summary": "18 Years to 50 Years · Male only" }, "enrollment_count": 30, "start_date": "2015-08", "completion_date": "2015-10", "has_results": false, "last_update_posted_date": "2016-08-24", "last_synced_at": "2026-09-09T08:04:43.859Z", "location_count": 1, "location_summary": "Phoenix, Arizona", "locations": [ { "city": "Phoenix", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT02876796" }, { "nct_id": "NCT02667977", "title": "Reexamining Hypotonic Intravenous Fluid Use", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Hyponatremia" ], "interventions": [ { "name": "0.9 Normal Saline", "type": "OTHER" }, { "name": "0.45 Normal Saline", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Ann & Robert H Lurie Children's Hospital of Chicago", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "6 Months", "maximum_age": "16 Years", "sex": "ALL", "summary": "6 Months to 16 Years" }, "enrollment_count": 0, "start_date": "2014-10", "completion_date": "2016-06", "has_results": false, "last_update_posted_date": "2016-01-29", "last_synced_at": "2026-09-09T08:04:43.859Z", "location_count": 1, "location_summary": "Chicago, Illinois", "locations": [ { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT02667977" }, { "nct_id": "NCT05187377", "title": "A Controlled Trial of Growth Hormone in Phelan-McDermid Syndrome and Idiopathic Autism", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Phelan-McDermid Syndrome", "Autism Spectrum Disorder (ASD)" ], "interventions": [ { "name": "Growth Hormone", "type": "DRUG" }, { "name": "Saline", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Icahn School of Medicine at Mount Sinai", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "2 Years", "maximum_age": "12 Years", "sex": "ALL", "summary": "2 Years to 12 Years" }, "enrollment_count": 32, "start_date": "2022-01-19", "completion_date": "2025-02-05", "has_results": false, "last_update_posted_date": "2025-04-20", "last_synced_at": "2026-09-09T08:04:43.859Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT05187377" }, { "nct_id": "NCT01996943", "title": "The HOLIDAY (HOw ALcohol InDuces Atrial TachYarrhythmias) Study", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Atrial Fibrillation", "Alcohol" ], "interventions": [ { "name": "Ethanol", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of California, San Francisco", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": "81 Years", "sex": "ALL", "summary": "21 Years to 81 Years" }, "enrollment_count": 100, "start_date": "2012-09", "completion_date": "2020-05", "has_results": true, "last_update_posted_date": "2021-03-16", "last_synced_at": "2026-09-09T08:04:43.859Z", "location_count": 1, "location_summary": "San Francisco, California", "locations": [ { "city": "San Francisco", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01996943" }, { "nct_id": "NCT02044094", "title": "Multiple Dose Study of Blockade of Opioid Effects by Injections of Buprenorphine in Participants With Opioid Disorder", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Opioid Use Disorder" ], "interventions": [ { "name": "Buprenorphine", "type": "DRUG" }, { "name": "buprenorphine and naloxone", "type": "DRUG" }, { "name": "hydromorphone", "type": "DRUG" }, { "name": "placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Indivior Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "18 Years to 55 Years" }, "enrollment_count": 39, "start_date": "2013-11", "completion_date": "2014-07", "has_results": true, "last_update_posted_date": "2018-04-24", "last_synced_at": "2026-09-09T08:04:43.859Z", "location_count": 1, "location_summary": "Overland Park, Kansas", "locations": [ { "city": "Overland Park", "state": "Kansas" } ], "official_url": "https://clinicaltrials.gov/study/NCT02044094" }, { "nct_id": "NCT07222241", "title": "Comparing Numbing Techniques in Mohs Micrographic Surgery", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Skin Cancer Face", "Skin Cancer Scalp" ], "interventions": [ { "name": "Nerve Block", "type": "OTHER" }, { "name": "Placebo Nerve Block", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Abramson Cancer Center at Penn Medicine", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 132, "start_date": "2026-01-27", "completion_date": "2026-06-26", "has_results": false, "last_update_posted_date": "2026-09-04", "last_synced_at": "2026-09-09T08:04:43.859Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT07222241" }, { "nct_id": "NCT04124042", "title": "Efficacy and Safety of XT-150 in Osteoarthritis of the Knee", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Osteoarthritis, Knee" ], "interventions": [ { "name": "XT-150", "type": "BIOLOGICAL" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "BIOLOGICAL", "DRUG" ], "sponsor": "Xalud Therapeutics, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "45 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "45 Years to 85 Years" }, "enrollment_count": 289, "start_date": "2020-02-14", "completion_date": "2022-04-26", "has_results": true, "last_update_posted_date": "2025-03-27", "last_synced_at": "2026-09-09T08:04:43.859Z", "location_count": 4, "location_summary": "La Mesa, California • Napa, California • Santa Monica, California + 1 more", "locations": [ { "city": "La Mesa", "state": "California" }, { "city": "Napa", "state": "California" }, { "city": "Santa Monica", "state": "California" }, { "city": "Winston-Salem", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT04124042" }, { "nct_id": "NCT01365793", "title": "Randomized Control Trial of Fluid Therapy for Pediatric Diabetic Ketoacidosis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Cerebral Edema", "Diabetic Ketoacidosis" ], "interventions": [ { "name": "0.45% saline replacement fluid", "type": "DRUG" }, { "name": "0.9% saline replacement fluid", "type": "DRUG" }, { "name": "0.45% saline intravenous fluid", "type": "DRUG" }, { "name": "0.9% saline Intravenous fluid", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of California, Davis", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": "17 Years", "sex": "ALL", "summary": "Up to 17 Years" }, "enrollment_count": 1389, "start_date": "2010-11", "completion_date": "2017-01", "has_results": true, "last_update_posted_date": "2018-06-25", "last_synced_at": "2026-09-09T08:04:43.859Z", "location_count": 13, "location_summary": "Sacramento, California • Aurora, Colorado • Wilmington, Delaware + 10 more", "locations": [ { "city": "Sacramento", "state": "California" }, { "city": "Aurora", "state": "Colorado" }, { "city": "Wilmington", "state": "Delaware" }, { "city": "Washington D.C.", "state": "District of Columbia" }, { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT01365793" }, { "nct_id": "NCT05464940", "title": "Impact of Intravenous Caffeine on Atrial Electrical Properties and Potential Arrythmia Induction", "overall_status": "NOT_YET_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Atrial Fibrillation" ], "interventions": [ { "name": "Intravenous caffeine", "type": "OTHER" }, { "name": "Masked Placebo", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Kansas City Heart Rhythm Research Foundation", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": "90 Years", "sex": "ALL", "summary": "21 Years to 90 Years" }, "enrollment_count": 100, "start_date": "2025-09", "completion_date": "2026-06", "has_results": false, "last_update_posted_date": "2025-08-28", "last_synced_at": "2026-09-09T08:04:43.859Z", "location_count": 9, "location_summary": "Loma Linda, California • Overland Park, Kansas • Independence, Missouri + 2 more", "locations": [ { "city": "Loma Linda", "state": "California" }, { "city": "Overland Park", "state": "Kansas" }, { "city": "Overland Park", "state": "Kansas" }, { "city": "Overland Park", "state": "Kansas" }, { "city": "Independence", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT05464940" }, { "nct_id": "NCT00281879", "title": "Donor Stem Cell Transplant or Donor White Blood Cell Infusions in Treating Patients With Hematologic Cancer", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Chronic Myeloproliferative Disorders", "Leukemia", "Lymphoma", "Multiple Myeloma and Plasma Cell Neoplasm", "Myelodysplastic Syndromes", "Myelodysplastic/Myeloproliferative Neoplasms", "Unusual Cancers of Childhood" ], "interventions": [ { "name": "anti-thymocyte globulin", "type": "BIOLOGICAL" }, { "name": "filgrastim", "type": "BIOLOGICAL" }, { "name": "busulfan", "type": "DRUG" }, { "name": "carmustine", "type": "DRUG" }, { "name": "cyclophosphamide", "type": "DRUG" }, { "name": "cyclosporine", "type": "DRUG" }, { "name": "cytarabine", "type": "DRUG" }, { "name": "etoposide", "type": "DRUG" }, { "name": "fludarabine phosphate", "type": "DRUG" }, { "name": "melphalan", "type": "DRUG" }, { "name": "methotrexate", "type": "DRUG" }, { "name": "methylprednisolone", "type": "DRUG" }, { "name": "mycophenolate mofetil", "type": "DRUG" }, { "name": "tacrolimus", "type": "DRUG" }, { "name": "peripheral blood stem cell transplantation", "type": "PROCEDURE" }, { "name": "umbilical cord blood transplantation", "type": "PROCEDURE" }, { "name": "radiation therapy", "type": "RADIATION" } ], "intervention_types": [ "BIOLOGICAL", "DRUG", "PROCEDURE", "RADIATION" ], "sponsor": "OHSU Knight Cancer Institute", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": "60 Years", "sex": "ALL", "summary": "Up to 60 Years" }, "enrollment_count": 200, "start_date": "2006-02", "completion_date": "2008-03", "has_results": true, "last_update_posted_date": "2017-09-27", "last_synced_at": "2026-09-09T08:04:43.859Z", "location_count": 1, "location_summary": "Portland, Oregon", "locations": [ { "city": "Portland", "state": "Oregon" } ], "official_url": "https://clinicaltrials.gov/study/NCT00281879" } ] }