{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=0.454%25+w%2Fw+stannous+fluoride", "query": { "intervention": "0.454% w/w stannous fluoride" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 13, "total_pages": 2, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=0.454%25+w%2Fw+stannous+fluoride&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-10-09T14:48:38.957Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT07704905", "title": "A Study to Investigate the Efficacy of an Experimental Dentifrice Containing Stannous Fluoride in Improving Gingival Health", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Dental Plaque", "Gingivitis" ], "interventions": [ { "name": "Test Dentifrice", "type": "DRUG" }, { "name": "Reference Dentifrice (Colgate Cavity Protection Dentifrice)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "HALEON", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 110, "start_date": "2026-07-13", "completion_date": "2026-09-30", "has_results": false, "last_update_posted_date": "2026-10-07", "last_synced_at": "2026-10-09T14:48:38.957Z", "location_count": 1, "location_summary": "Fort Wayne, Indiana", "locations": [ { "city": "Fort Wayne", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT07704905" }, { "nct_id": "NCT06354270", "title": "A Clinical Study to Evaluate the Anti-Sensitivity Efficacy of a Stannous Fluoride Toothpaste in a Population of Dentin Hypersensitivity Sufferers", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Dentin Sensitivity" ], "interventions": [ { "name": "Stannous fluoride toothpaste", "type": "DRUG" }, { "name": "Regular fluoride toothpaste (Crest Cavity Protection)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "HALEON", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 115, "start_date": "2024-04-11", "completion_date": "2024-06-23", "has_results": true, "last_update_posted_date": "2025-06-25", "last_synced_at": "2026-10-09T14:48:38.957Z", "location_count": 1, "location_summary": "Melbourne, Florida", "locations": [ { "city": "Melbourne", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT06354270" }, { "nct_id": "NCT04123665", "title": "A Phase 3 Clinical Study Investigating the Gingivitis Efficacy of a Test Dentifrice Containing Stannous Fluoride", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Gingivitis" ], "interventions": [ { "name": "Stannous fluoride", "type": "DRUG" }, { "name": "Sodium monofluorophosphate", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "GlaxoSmithKline", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 98, "start_date": "2013-05-28", "completion_date": "2013-12-11", "has_results": true, "last_update_posted_date": "2020-01-31", "last_synced_at": "2026-10-09T14:48:38.957Z", "location_count": 1, "location_summary": "Fort Wayne, Indiana", "locations": [ { "city": "Fort Wayne", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT04123665" }, { "nct_id": "NCT03296072", "title": "In Situ Erosion Study to Investigate the Effectiveness of an Experimental Toothpaste", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Tooth Erosion" ], "interventions": [ { "name": "0.254% w/w sodium fluoride and 5% KNO3", "type": "DRUG" }, { "name": "0.454% w/w stannous fluoride", "type": "DRUG" }, { "name": "5% KNO3", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "GlaxoSmithKline", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 62, "start_date": "2017-11-13", "completion_date": "2018-01-16", "has_results": true, "last_update_posted_date": "2020-09-16", "last_synced_at": "2026-10-09T14:48:38.957Z", "location_count": 1, "location_summary": "Indianapolis, Indiana", "locations": [ { "city": "Indianapolis", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT03296072" }, { "nct_id": "NCT06660069", "title": "A Study to Evaluate the Efficacy of a Stannous Fluoride Toothpaste With a Cetylpyridinium Chloride Mouthwash in Improving Gingival Health and Reducing Plaque Accumulation", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Dental Plaque", "Gingivitis" ], "interventions": [ { "name": "Stannous Fluoride Toothpaste (Parodontax Complete Protection Toothpaste)", "type": "DRUG" }, { "name": "CPC Mouthwash (Parodontax Active Gum Health Mouthwash)", "type": "DRUG" }, { "name": "Regular Fluoride Toothpaste (Crest Cavity Protection)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "HALEON", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 199, "start_date": "2024-11-18", "completion_date": "2025-03-11", "has_results": true, "last_update_posted_date": "2026-03-18", "last_synced_at": "2026-10-09T14:48:38.957Z", "location_count": 1, "location_summary": "Fort Wayne, Indiana", "locations": [ { "city": "Fort Wayne", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT06660069" }, { "nct_id": "NCT07398846", "title": "Efficacy of a Stannous Fluoride Toothpaste, Cetylpyridinium Chloride Mouthwash, and Battery Toothbrush Regimen in Reducing Established Dental Plaque and Gingivitis.", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Plaque" ], "interventions": [ { "name": "0.454%Stannous fluoride toothpaste", "type": "DRUG" }, { "name": "0.075% Cetylpyridinium Chloride (CPC) and 0.28% zinc lactatmouthwashe", "type": "DRUG" }, { "name": "0.76% Sodium Monofluorophosphate (Na MFP) toothpaste", "type": "DRUG" }, { "name": "0.022% Sodium Fluoride mouthwash", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Colgate Palmolive", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 134, "start_date": "2026-01-26", "completion_date": "2026-04-29", "has_results": false, "last_update_posted_date": "2026-05-22", "last_synced_at": "2026-10-09T14:48:38.957Z", "location_count": 1, "location_summary": "Melbourne, Florida", "locations": [ { "city": "Melbourne", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT07398846" }, { "nct_id": "NCT02750943", "title": "Potential of Stannous Fluoride Toothpaste to Reduce Gum Disease", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Gingivitis" ], "interventions": [ { "name": "Stannous Fluoride", "type": "DRUG" }, { "name": "Sodium Monofluorophosphate", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "GlaxoSmithKline", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 253, "start_date": "2015-11-01", "completion_date": "2016-03-04", "has_results": true, "last_update_posted_date": "2017-10-26", "last_synced_at": "2026-10-09T14:48:38.957Z", "location_count": 1, "location_summary": "Las Vegas, Nevada", "locations": [ { "city": "Las Vegas", "state": "Nevada" } ], "official_url": "https://clinicaltrials.gov/study/NCT02750943" }, { "nct_id": "NCT01827670", "title": "Investigating the Efficacy of a Dentifrice in Providing Long Term Relief From Dentinal Hypersensitivity", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Dentine Hypersensitivity" ], "interventions": [ { "name": "Stannous fluoride", "type": "DRUG" }, { "name": "Sodium monofluorophosphate", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "GlaxoSmithKline", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 119, "start_date": "2013-02", "completion_date": "2013-05", "has_results": true, "last_update_posted_date": "2015-01-26", "last_synced_at": "2026-10-09T14:48:38.957Z", "location_count": 1, "location_summary": "Fort Wayne, Indiana", "locations": [ { "city": "Fort Wayne", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT01827670" }, { "nct_id": "NCT06244303", "title": "Clinical Research Study to Assess the Efficacy of Two Brushing Regimens in the Reduction of Established Dental Plaque and Gingivitis.", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Gingivitis", "Plaque" ], "interventions": [ { "name": "manual Tooth Brush + Colgate Total TP (0.454% SnF, 1100 ppm F)", "type": "DRUG" }, { "name": "manual toothbrush + Colgate dental cream", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Colgate Palmolive", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 82, "start_date": "2024-01-22", "completion_date": "2024-04-16", "has_results": false, "last_update_posted_date": "2026-03-19", "last_synced_at": "2026-10-09T14:48:38.957Z", "location_count": 1, "location_summary": "Costa Mesa, California", "locations": [ { "city": "Costa Mesa", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06244303" }, { "nct_id": "NCT06359028", "title": "Clinical Study to Evaluate the Anti-sensitivity Efficacy of a Stannous Fluoride Toothpaste in a Population of Dentin Hypersensitivity Sufferers", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Dentin Sensitivity" ], "interventions": [ { "name": "Stannous fluoride toothpaste", "type": "DRUG" }, { "name": "Crest cavity protection toothpaste", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "HALEON", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 111, "start_date": "2024-03-25", "completion_date": "2024-06-20", "has_results": true, "last_update_posted_date": "2025-06-24", "last_synced_at": "2026-10-09T14:48:38.957Z", "location_count": 1, "location_summary": "Fort Wayne, Indiana", "locations": [ { "city": "Fort Wayne", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT06359028" } ] }