{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=0.5+mg+DEX", "query": { "intervention": "0.5 mg DEX" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 10, "total_pages": 1, "next_page_url": null, "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-11T21:36:09.224Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT07369128", "title": "Propofol-Only Versus Dexmedetomidine-Propofol in Children Undergoing Magnetic Resonance Imaging", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "MRI Sedation", "Pediatric Sedation", "Propofol Dosage", "Emergence Delirium, Anesthesia", "Recovery Time", "Dexmedetomidine" ], "interventions": [ { "name": "Dexmedetomidine (IV) 0.5 mcg/kg", "type": "DRUG" }, { "name": "Propofol (IV) 2-4 mg/kg", "type": "DRUG" }, { "name": "Dexmedetomidine (IV) 1 mcg/kg", "type": "DRUG" }, { "name": "Propofol (IV) 1-2 mg/kg", "type": "DRUG" }, { "name": "Propofol (IV) Infusion 250 mcg/kg/min", "type": "DRUG" }, { "name": "Propofol (IV) Infusion 150 mcg/kg/min", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Boston Children's Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "1 Year", "maximum_age": "12 Years", "sex": "ALL", "summary": "1 Year to 12 Years" }, "enrollment_count": 105, "start_date": "2026-06", "completion_date": "2028-03", "has_results": false, "last_update_posted_date": "2026-05-29", "last_synced_at": "2026-09-11T21:36:09.224Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT07369128" }, { "nct_id": "NCT00002548", "title": "SWOG-9321 Melphalan, TBI, and Transplant vs Combo Chemo in Untreated Myeloma", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Multiple Myeloma" ], "interventions": [ { "name": "recombinant interferon alfa", "type": "BIOLOGICAL" }, { "name": "carmustine", "type": "DRUG" }, { "name": "cyclophosphamide", "type": "DRUG" }, { "name": "dexamethasone", "type": "DRUG" }, { "name": "doxorubicin hydrochloride", "type": "DRUG" }, { "name": "melphalan", "type": "DRUG" }, { "name": "prednisone", "type": "DRUG" }, { "name": "vincristine sulfate", "type": "DRUG" }, { "name": "allogeneic bone marrow transplantation", "type": "PROCEDURE" }, { "name": "autologous bone marrow transplantation", "type": "PROCEDURE" }, { "name": "peripheral blood stem cell transplantation", "type": "PROCEDURE" }, { "name": "radiation therapy", "type": "RADIATION" } ], "intervention_types": [ "BIOLOGICAL", "DRUG", "PROCEDURE", "RADIATION" ], "sponsor": "SWOG Cancer Research Network", "sponsor_class": "NETWORK", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 899, "start_date": "1994-01", "completion_date": "2006-11", "has_results": false, "last_update_posted_date": "2015-03-06", "last_synced_at": "2026-09-11T21:36:09.224Z", "location_count": 34, "location_summary": "Scottsdale, Arizona • Denver, Colorado • Tampa, Florida + 25 more", "locations": [ { "city": "Scottsdale", "state": "Arizona" }, { "city": "Denver", "state": "Colorado" }, { "city": "Tampa", "state": "Florida" }, { "city": "Chicago", "state": "Illinois" }, { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT00002548" }, { "nct_id": "NCT01017237", "title": "Dexmedetomidine Sedation With Third Molar Surgery", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Anesthesia" ], "interventions": [ { "name": "Dexmedetomidine", "type": "DRUG" }, { "name": "Midazolam", "type": "DRUG" }, { "name": "Ketamine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of North Carolina, Chapel Hill", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "30 Years", "sex": "ALL", "summary": "18 Years to 30 Years" }, "enrollment_count": 18, "start_date": "2009-07", "completion_date": "2011-12", "has_results": true, "last_update_posted_date": "2013-06-17", "last_synced_at": "2026-09-11T21:36:09.224Z", "location_count": 1, "location_summary": "Chapel Hill, North Carolina", "locations": [ { "city": "Chapel Hill", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT01017237" }, { "nct_id": "NCT02985697", "title": "Safety and Efficacy of Intranasal Dexmedetomidine", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Safety and Efficacy of Intranasal Dexmedetomidine" ], "interventions": [ { "name": "Dexmedetomidine", "type": "DRUG" }, { "name": "Midazolam Hydrochloride", "type": "DRUG" }, { "name": "Nitrous Oxide", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Bon Secours Pediatric Dental Associates", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "3 Years", "maximum_age": "6 Years", "sex": "ALL", "summary": "3 Years to 6 Years" }, "enrollment_count": 100, "start_date": "2017-01", "completion_date": "2018-06", "has_results": false, "last_update_posted_date": "2016-12-07", "last_synced_at": "2026-09-11T21:36:09.224Z", "location_count": 1, "location_summary": "Richmond, Virginia", "locations": [ { "city": "Richmond", "state": "Virginia" } ], "official_url": "https://clinicaltrials.gov/study/NCT02985697" }, { "nct_id": "NCT05279092", "title": "Yale Steroid Enhanced Versus Exparel Nerveblock TKA RCT Study", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Total Knee Replacement", "Knee Arthroplasty" ], "interventions": [ { "name": "Bupivacaine-Liposomal Bupivacaine", "type": "DRUG" }, { "name": "Bupivacaine -Dexamethasone Sodium Phosphate-Methylprednisolone Acetate", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Yale University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 250, "start_date": "2022-09-08", "completion_date": "2028-03", "has_results": false, "last_update_posted_date": "2026-07-23", "last_synced_at": "2026-09-11T21:36:09.224Z", "location_count": 2, "location_summary": "New Haven, Connecticut", "locations": [ { "city": "New Haven", "state": "Connecticut" }, { "city": "New Haven", "state": "Connecticut" } ], "official_url": "https://clinicaltrials.gov/study/NCT05279092" }, { "nct_id": "NCT00519584", "title": "Interscalene Nerve Blocks With Ropivacaine Alone, With Dexamethasone, Plus Systemic Dexamethasone", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Pain" ], "interventions": [ { "name": "Ropivacaine", "type": "DRUG" }, { "name": "dex", "type": "DRUG" }, { "name": "Bupivacaine", "type": "DRUG" }, { "name": "Saline", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "The Cleveland Clinic", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 218, "start_date": "2007-07", "completion_date": "2009-03", "has_results": true, "last_update_posted_date": "2017-07-21", "last_synced_at": "2026-09-11T21:36:09.224Z", "location_count": 2, "location_summary": "Cleveland, Ohio • Euclid, Ohio", "locations": [ { "city": "Cleveland", "state": "Ohio" }, { "city": "Euclid", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT00519584" }, { "nct_id": "NCT02952222", "title": "The Synergistic Effect of Dexmedetomidine on Propofol for Sedation for Pediatric Endoscopy", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Anesthesia" ], "interventions": [ { "name": "Dexmedetomidine", "type": "DRUG" }, { "name": "Propofol (Group P)", "type": "DRUG" }, { "name": "Propofol (Group DP)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Keira Mason", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "7 Years", "maximum_age": "18 Years", "sex": "ALL", "summary": "7 Years to 18 Years" }, "enrollment_count": 39, "start_date": "2018-05-11", "completion_date": "2019-09-12", "has_results": true, "last_update_posted_date": "2024-05-10", "last_synced_at": "2026-09-11T21:36:09.224Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT02952222" }, { "nct_id": "NCT00564954", "title": "A Study of Dex-methylphenidate Extended Release in Children (6-12 Years) With Attention-Deficit/Hyperactivity Disorder (ADHD)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Attention Deficit Hyperactivity Disorder" ], "interventions": [ { "name": "Dex-methylphenidate hydrochloride extended-release (Focalin XR)", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Novartis Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "6 Years", "maximum_age": "12 Years", "sex": "ALL", "summary": "6 Years to 12 Years" }, "enrollment_count": 86, "start_date": "2007-10", "completion_date": "2007-11", "has_results": true, "last_update_posted_date": "2012-04-27", "last_synced_at": "2026-09-11T21:36:09.224Z", "location_count": 5, "location_summary": "Little Rock, Arkansas • Winter Park, Florida • Las Vegas, Nevada + 2 more", "locations": [ { "city": "Little Rock", "state": "Arkansas" }, { "city": "Winter Park", "state": "Florida" }, { "city": "Las Vegas", "state": "Nevada" }, { "city": "Houston", "state": "Texas" }, { "city": "Lubbock", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00564954" }, { "nct_id": "NCT01965366", "title": "Dexamethasone Plus Virtual Reality Exposure Therapy for PTSD", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "PTSD" ], "interventions": [ { "name": "Virtual reality exposure therapy", "type": "BEHAVIORAL" }, { "name": "0.5 mg DEX", "type": "DRUG" } ], "intervention_types": [ "BEHAVIORAL", "DRUG" ], "sponsor": "Emory University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "21 Years to 65 Years" }, "enrollment_count": 27, "start_date": "2013-10", "completion_date": "2017-06", "has_results": true, "last_update_posted_date": "2018-07-12", "last_synced_at": "2026-09-11T21:36:09.224Z", "location_count": 1, "location_summary": "Atlanta, Georgia", "locations": [ { "city": "Atlanta", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT01965366" }, { "nct_id": "NCT02404220", "title": "Safety and Efficacy of Entospletinib With Vincristine and Dexamethasone in Adults With Relapsed or Refractory Acute Lymphoblastic Leukemia (ALL)", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Acute Lymphoblastic Leukemia" ], "interventions": [ { "name": "Entospletinib", "type": "DRUG" }, { "name": "Vincristine", "type": "DRUG" }, { "name": "Dexamethasone", "type": "DRUG" }, { "name": "CNS Prophylaxis", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Gilead Sciences", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 30, "start_date": "2015-05-06", "completion_date": "2018-12-17", "has_results": true, "last_update_posted_date": "2020-01-02", "last_synced_at": "2026-09-11T21:36:09.224Z", "location_count": 10, "location_summary": "Duarte, California • Los Angeles, California • Orange, California + 7 more", "locations": [ { "city": "Duarte", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Orange", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT02404220" } ] }