{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=12-week+lifestyle+modification&page=2",
    "query": {
      "intervention": "12-week lifestyle modification",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 212,
    "total_pages": 22,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=12-week+lifestyle+modification&page=3&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=12-week+lifestyle+modification&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-30T13:20:00.916Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04157101",
      "title": "Health Coaching for Chronic Multisymptom Illness",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pain Predominant Chronic Multisymptom Illness"
      ],
      "interventions": [
        {
          "name": "Health Coaching",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Supportive Psychotherapy",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 260,
      "start_date": "2020-04-30",
      "completion_date": "2025-09-23",
      "has_results": false,
      "last_update_posted_date": "2026-04-20",
      "last_synced_at": "2026-09-30T13:20:00.916Z",
      "location_count": 1,
      "location_summary": "East Orange, New Jersey",
      "locations": [
        {
          "city": "East Orange",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04157101"
    },
    {
      "nct_id": "NCT07400419",
      "title": "Effects of Resistance Exercise Among TGD Individuals Initiating Estrogen-Based Gender-Affirming Hormone Therapy",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Muscle Mass and Strength"
      ],
      "interventions": [
        {
          "name": "Resistance Exercise Program",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Nutrition and Exercise Counseling",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "MALE",
        "summary": "18 Years and older · Male only"
      },
      "enrollment_count": 40,
      "start_date": "2026-04-16",
      "completion_date": "2028-04-01",
      "has_results": false,
      "last_update_posted_date": "2026-09-11",
      "last_synced_at": "2026-09-30T13:20:00.916Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07400419"
    },
    {
      "nct_id": "NCT07226102",
      "title": "Virtual Mental Health Intervention to Address Fear of Progression for Women With High Risk or Stage III-IV Gynecologic or Breast Cancer",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anatomic Stage III Breast Cancer AJCC v8",
        "Anatomic Stage IV Breast Cancer AJCC v8",
        "Endometrial Carcinoma",
        "Endometrial Endometrioid Adenocarcinoma",
        "Female Reproductive System Neoplasm",
        "Stage II Ovarian Cancer AJCC v8",
        "Stage III Ovarian Cancer AJCC v8",
        "Stage III Vaginal Cancer AJCC v8",
        "Stage III Vulvar Cancer AJCC v8",
        "Stage IV Ovarian Cancer AJCC v8",
        "Stage IV Vaginal Cancer AJCC v8",
        "Stage IV Vulvar Cancer AJCC v8",
        "Triple-Negative Breast Carcinoma"
      ],
      "interventions": [
        {
          "name": "Behavioral Intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Educational Intervention",
          "type": "OTHER"
        },
        {
          "name": "Internet-Based Intervention",
          "type": "OTHER"
        },
        {
          "name": "Interview",
          "type": "OTHER"
        },
        {
          "name": "Survey Administration",
          "type": "OTHER"
        },
        {
          "name": "Virtual Technology Intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "City of Hope Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 0,
      "start_date": "2026-07-16",
      "completion_date": "2026-07-16",
      "has_results": false,
      "last_update_posted_date": "2026-02-04",
      "last_synced_at": "2026-09-30T13:20:00.916Z",
      "location_count": 12,
      "location_summary": "Arcadia, California • Duarte, California • Irvine, California + 8 more",
      "locations": [
        {
          "city": "Arcadia",
          "state": "California"
        },
        {
          "city": "Duarte",
          "state": "California"
        },
        {
          "city": "Irvine",
          "state": "California"
        },
        {
          "city": "Lancaster",
          "state": "California"
        },
        {
          "city": "Long Beach",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07226102"
    },
    {
      "nct_id": "NCT00897975",
      "title": "Red Yeast Rice and Phytosterols In Statin Intolerance",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Hyperlipidemia"
      ],
      "interventions": [
        {
          "name": "red yeast rice",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "phytosterol",
          "type": "DRUG"
        },
        {
          "name": "therapeutic lifestyle program",
          "type": "BEHAVIORAL"
        },
        {
          "name": "placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "Chestnut Hill Health System",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 200,
      "start_date": "2009-07",
      "completion_date": "2011-07",
      "has_results": false,
      "last_update_posted_date": "2011-07-18",
      "last_synced_at": "2026-09-30T13:20:00.916Z",
      "location_count": 2,
      "location_summary": "Abington, Pennsylvania • Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Abington",
          "state": "Pennsylvania"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00897975"
    },
    {
      "nct_id": "NCT03246672",
      "title": "Development of a Weight Maintenance Intervention for Bariatric Surgery Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity, Morbid"
      ],
      "interventions": [
        {
          "name": "maintenance intervention",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 33,
      "start_date": "2018-01-03",
      "completion_date": "2018-07-31",
      "has_results": true,
      "last_update_posted_date": "2019-08-19",
      "last_synced_at": "2026-09-30T13:20:00.916Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03246672"
    },
    {
      "nct_id": "NCT05715372",
      "title": "Genetic Evaluation and Modification of Lifestyles to Improve Female Life Expectancy",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Menopause Syndrome",
        "Inflammation",
        "Inflammatory Response",
        "Aging",
        "Menopause",
        "Telomere Shortening",
        "Stress Oxidative"
      ],
      "interventions": [
        {
          "name": "Mediterranean diet",
          "type": "BEHAVIORAL"
        },
        {
          "name": "AHA walking program",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Mindfulness-based stress reduction",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Unstructured Mediterranean diet",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Unstructured walking program",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Unstructured stress reduction",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Rush University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "60 Years",
        "sex": "FEMALE",
        "summary": "40 Years to 60 Years · Female only"
      },
      "enrollment_count": 5,
      "start_date": "2021-06-22",
      "completion_date": "2021-06-22",
      "has_results": false,
      "last_update_posted_date": "2023-02-13",
      "last_synced_at": "2026-09-30T13:20:00.916Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05715372"
    },
    {
      "nct_id": "NCT02143817",
      "title": "Whole Body Vibration Combined With L-citrulline Supplementation on Cardiovascular Function and Body Composition",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity",
        "Pre-hypertension",
        "Hypertension"
      ],
      "interventions": [
        {
          "name": "L-citrulline supplementation",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Whole Body Vibration Training",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "OTHER"
      ],
      "sponsor": "Florida State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "70 Years",
        "sex": "FEMALE",
        "summary": "50 Years to 70 Years · Female only"
      },
      "enrollment_count": 60,
      "start_date": "2013-03",
      "completion_date": "2014-01",
      "has_results": false,
      "last_update_posted_date": "2015-03-10",
      "last_synced_at": "2026-09-30T13:20:00.916Z",
      "location_count": 1,
      "location_summary": "Tallahassee, Florida",
      "locations": [
        {
          "city": "Tallahassee",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02143817"
    },
    {
      "nct_id": "NCT03560635",
      "title": "Feasibility and Preliminary Efficacy of a Reverse Diet as a Novel Weight Loss Maintenance Strategy for Weight-Reduced Adults With Overweight/Obesity",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Overweight and Obesity",
        "Weight Loss Maintenance",
        "Dietary Habits"
      ],
      "interventions": [
        {
          "name": "Weight Loss Maintenance (Control vs. Reverse Diet)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "21 Years to 70 Years"
      },
      "enrollment_count": 24,
      "start_date": "2018-02-14",
      "completion_date": "2022-01-25",
      "has_results": false,
      "last_update_posted_date": "2022-04-19",
      "last_synced_at": "2026-09-30T13:20:00.916Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03560635"
    },
    {
      "nct_id": "NCT06116435",
      "title": "A Pilot Factorial Trial of an Integrated Lifestyle Intervention",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Physical Inactivity",
        "Overweight and Obesity"
      ],
      "interventions": [
        {
          "name": "Prevent T2",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Move group-based classes",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Fitness Membership",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Mental Imagery",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Move 1:1 Support",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 64,
      "start_date": "2023-12-04",
      "completion_date": "2027-03",
      "has_results": false,
      "last_update_posted_date": "2024-05-14",
      "last_synced_at": "2026-09-30T13:20:00.916Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06116435"
    },
    {
      "nct_id": "NCT07220681",
      "title": "Integrated Health Care for PTSD",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Posttraumatic Stress Disorder (PTSD)"
      ],
      "interventions": [
        {
          "name": "Yoga and meditation",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Wellness",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Positive affect",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Information",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "Veterans Medical Research Foundation",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 300,
      "start_date": "2026-04-23",
      "completion_date": "2029-09-30",
      "has_results": false,
      "last_update_posted_date": "2026-09-23",
      "last_synced_at": "2026-09-30T13:20:00.916Z",
      "location_count": 5,
      "location_summary": "Little Rock, Arkansas • San Diego, California • Durham, North Carolina + 2 more",
      "locations": [
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        },
        {
          "city": "Portland",
          "state": "Oregon"
        },
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07220681"
    }
  ]
}