{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=2+mg+IV+hydromorphone", "query": { "intervention": "2 mg IV hydromorphone" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 21, "total_pages": 3, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=2+mg+IV+hydromorphone&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-24T15:58:33.473Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT02219581", "title": "Steroids in Total Knee Arthroplasty", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Postoperative Pain", "Inflammation", "Osteoarthritis" ], "interventions": [ { "name": "Dexamethasone 10 mg", "type": "DRUG" }, { "name": "Dexamethasone 20 mg", "type": "DRUG" }, { "name": "Standard multimodal pain management regimen", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Thomas L Bradbury", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "100 Years", "sex": "ALL", "summary": "18 Years to 100 Years" }, "enrollment_count": 1, "start_date": "2014-10-16", "completion_date": "2015-12-01", "has_results": true, "last_update_posted_date": "2022-10-04", "last_synced_at": "2026-09-24T15:58:33.473Z", "location_count": 1, "location_summary": "Tucker, Georgia", "locations": [ { "city": "Tucker", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT02219581" }, { "nct_id": "NCT02449369", "title": "Intra-Venous Acetaminophen and Muscle Relaxants After Total Knee", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Unilateral Knee Arthroplasty" ], "interventions": [ { "name": "Preop acetaminophen IV", "type": "DRUG" }, { "name": "Preop orphenadrine IV", "type": "DRUG" }, { "name": "Postop oral oxycodone & acetaminophen", "type": "DRUG" }, { "name": "Postop hydromorphone IV", "type": "DRUG" }, { "name": "Postop oral orphenadrine", "type": "DRUG" }, { "name": "Postop oral oxycodone", "type": "DRUG" }, { "name": "Postop acetaminophen IV", "type": "DRUG" }, { "name": "Postop orphenadrine IV", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "AdventHealth", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "18 Years to 85 Years" }, "enrollment_count": 180, "start_date": "2015-04", "completion_date": "2016-09", "has_results": false, "last_update_posted_date": "2017-08-31", "last_synced_at": "2026-09-24T15:58:33.473Z", "location_count": 1, "location_summary": "Winter Park, Florida", "locations": [ { "city": "Winter Park", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT02449369" }, { "nct_id": "NCT00305110", "title": "Safety of Hydromorphone in Adult Patients Presenting to the Emergency Department With Acute Severe Pain", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Acute Pain" ], "interventions": [ { "name": "2 mg IV hydromorphone", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Montefiore Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "21 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "21 Years to 65 Years" }, "enrollment_count": 298, "start_date": "2006-01", "completion_date": "2006-10", "has_results": true, "last_update_posted_date": "2018-08-20", "last_synced_at": "2026-09-24T15:58:33.473Z", "location_count": 1, "location_summary": "The Bronx, New York", "locations": [ { "city": "The Bronx", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT00305110" }, { "nct_id": "NCT03789318", "title": "Study in Subjects Undergoing Complete Abdominoplasty", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Postsurgical Pain" ], "interventions": [ { "name": "CA-008 5 mg", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Bupivacaine Hydrochloride", "type": "DRUG" }, { "name": "Hydromorphone", "type": "DRUG" }, { "name": "Fentanyl", "type": "DRUG" }, { "name": "Acetaminophen", "type": "DRUG" }, { "name": "Oxycodone", "type": "DRUG" }, { "name": "CA-008 10 mg", "type": "DRUG" }, { "name": "CA-008 15 mg", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Concentric Analgesics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 54, "start_date": "2018-12-03", "completion_date": "2019-06-12", "has_results": true, "last_update_posted_date": "2024-03-19", "last_synced_at": "2026-09-24T15:58:33.473Z", "location_count": 1, "location_summary": "Pasadena, California", "locations": [ { "city": "Pasadena", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03789318" }, { "nct_id": "NCT01311895", "title": "Clinical Trial Comparing Two Protocols Using Intravenous (IV) Hydromorphone", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Acute Pain" ], "interventions": [ { "name": "H2O", "type": "DRUG" }, { "name": "1+1", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Montefiore Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "21 Years to 65 Years" }, "enrollment_count": 350, "start_date": "2011-01", "completion_date": "2011-11", "has_results": true, "last_update_posted_date": "2018-05-18", "last_synced_at": "2026-09-24T15:58:33.473Z", "location_count": 1, "location_summary": "The Bronx, New York", "locations": [ { "city": "The Bronx", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT01311895" }, { "nct_id": "NCT02958566", "title": "Multimodal Narcotic Limited Perioperative Pain Control With Colorectal Surgery", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Colon Cancer", "Colon Diverticulosis", "Colonic Neoplasms", "Colonic Diverticulitis", "Pain, Postoperative", "Ileus", "Ileus Paralytic", "Ileus; Mechanical", "Constipation Drug Induced", "Constipation", "Rectum Cancer", "Rectum Neoplasm" ], "interventions": [ { "name": "Acetaminophen", "type": "DRUG" }, { "name": "Gabapentin", "type": "DRUG" }, { "name": "Orphenadrine", "type": "DRUG" }, { "name": "Lidocaine", "type": "DRUG" }, { "name": "Marcaine", "type": "DRUG" }, { "name": "Ketamine", "type": "DRUG" }, { "name": "Methadone", "type": "DRUG" }, { "name": "Tramadol", "type": "DRUG" }, { "name": "Ketorolac", "type": "DRUG" }, { "name": "Morphine Sulfate", "type": "DRUG" }, { "name": "Fentanyl", "type": "DRUG" }, { "name": "Dilaudid", "type": "DRUG" }, { "name": "Hydrocodone-Acetaminophen Tab 5-325 MG", "type": "DRUG" }, { "name": "HYDROCODONE/ACETAMINOPHEN 5 Mg-325 Mg ORAL TABLET", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Illinois College of Medicine at Peoria", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 80, "start_date": "2017-01", "completion_date": "2018-12", "has_results": false, "last_update_posted_date": "2017-03-20", "last_synced_at": "2026-09-24T15:58:33.473Z", "location_count": 1, "location_summary": "Peoria, Illinois", "locations": [ { "city": "Peoria", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT02958566" }, { "nct_id": "NCT04464512", "title": "Suboxone User Perioperative Early Referral and Enhanced Recovery After Surgery- Orthopaedic Trauma Surgery Population", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Addiction Opiate", "Chronic Pain", "Fractures, Bone", "Buprenorphine Dependence" ], "interventions": [ { "name": "Sufentanil", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "West Virginia University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 0, "start_date": "2020-01-10", "completion_date": "2021-08-22", "has_results": false, "last_update_posted_date": "2022-12-12", "last_synced_at": "2026-09-24T15:58:33.473Z", "location_count": 1, "location_summary": "Morgantown, West Virginia", "locations": [ { "city": "Morgantown", "state": "West Virginia" } ], "official_url": "https://clinicaltrials.gov/study/NCT04464512" }, { "nct_id": "NCT01429298", "title": "Comparing Intravenous Hydromorphone to Usual Care", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Pain" ], "interventions": [ { "name": "Hydromorphone", "type": "DRUG" }, { "name": "Usual care", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Montefiore Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "21 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "21 Years to 65 Years" }, "enrollment_count": 350, "start_date": "2010-03", "completion_date": "2010-11", "has_results": true, "last_update_posted_date": "2018-05-18", "last_synced_at": "2026-09-24T15:58:33.473Z", "location_count": 1, "location_summary": "The Bronx, New York", "locations": [ { "city": "The Bronx", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT01429298" }, { "nct_id": "NCT03115151", "title": "Epidural and Intravenous Patient-Controlled Analgesia Following Lumbar Spinal Fusion Surgery", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Pain" ], "interventions": [ { "name": "Bupivacaine", "type": "DRUG" }, { "name": "Hydromorphone", "type": "DRUG" }, { "name": "Fentanyl", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Texas Southwestern Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 46, "start_date": "2017-05-08", "completion_date": "2023-04-04", "has_results": true, "last_update_posted_date": "2023-10-26", "last_synced_at": "2026-09-24T15:58:33.473Z", "location_count": 2, "location_summary": "Dallas, Texas", "locations": [ { "city": "Dallas", "state": "Texas" }, { "city": "Dallas", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT03115151" }, { "nct_id": "NCT03330119", "title": "Determining the Effect of an \"Alternate Recovery Protocol\" Versus Current Standard of Care After Cesarean Section", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Pregnancy Related", "Narcotic Use" ], "interventions": [ { "name": "Alternate Management", "type": "DRUG" }, { "name": "Control", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Brest, Norman A., M.D.", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "45 Years", "sex": "FEMALE", "summary": "18 Years to 45 Years · Female only" }, "enrollment_count": 1494, "start_date": "2017-10-04", "completion_date": "2018-06-20", "has_results": true, "last_update_posted_date": "2021-03-02", "last_synced_at": "2026-09-24T15:58:33.473Z", "location_count": 1, "location_summary": "Wynnewood, Pennsylvania", "locations": [ { "city": "Wynnewood", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT03330119" } ] }