{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=200mg+of+Caffeine",
    "query": {
      "intervention": "200mg of Caffeine"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 15,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=200mg+of+Caffeine&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-14T07:24:29.444Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05588934",
      "title": "Caffeine Optimization Versus Standard Caffeine Dosage (2B-2)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sleep Deprivation",
        "Caffeine"
      ],
      "interventions": [
        {
          "name": "Caffeine Gum",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo Gum",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "OTHER"
      ],
      "sponsor": "University of Arizona",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "39 Years",
        "sex": "ALL",
        "summary": "18 Years to 39 Years"
      },
      "enrollment_count": 180,
      "start_date": "2023-06-09",
      "completion_date": "2026-03",
      "has_results": false,
      "last_update_posted_date": "2025-11-04",
      "last_synced_at": "2026-09-14T07:24:29.444Z",
      "location_count": 2,
      "location_summary": "Tucson, Arizona",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05588934"
    },
    {
      "nct_id": "NCT05592561",
      "title": "Impact of Supplements on Stress Markers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Physiological Stress"
      ],
      "interventions": [
        {
          "name": "mental stress task",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Texas State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 109,
      "start_date": "2022-01-25",
      "completion_date": "2023-04-10",
      "has_results": false,
      "last_update_posted_date": "2023-04-12",
      "last_synced_at": "2026-09-14T07:24:29.444Z",
      "location_count": 1,
      "location_summary": "San Marcos, Texas",
      "locations": [
        {
          "city": "San Marcos",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05592561"
    },
    {
      "nct_id": "NCT06763172",
      "title": "Effects of Caffeine on Reinforcement Learning in Healthy Adults Using PET/MRI",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Healthy",
        "Caffeine",
        "Adenosine",
        "Dopamine D2/3 Receptor Availability"
      ],
      "interventions": [
        {
          "name": "Caffeine (200 mg)",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Hsiao-Ying Wey",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 12,
      "start_date": "2023-05-17",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-01-09",
      "last_synced_at": "2026-09-14T07:24:29.444Z",
      "location_count": 1,
      "location_summary": "Charlestown, Massachusetts",
      "locations": [
        {
          "city": "Charlestown",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06763172"
    },
    {
      "nct_id": "NCT01950520",
      "title": "Study of Human Non-Shivering Thermogenesis and Basal Metabolic Rate",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Healthy Volunteers"
      ],
      "interventions": [
        {
          "name": "Propranolol",
          "type": "DRUG"
        },
        {
          "name": "Pindolol",
          "type": "DRUG"
        },
        {
          "name": "Dantrolene",
          "type": "DRUG"
        },
        {
          "name": "Magnesium Sulfate",
          "type": "DRUG"
        },
        {
          "name": "Caffeine",
          "type": "DRUG"
        },
        {
          "name": "Qsymia",
          "type": "DRUG"
        },
        {
          "name": "Topiramate",
          "type": "DRUG"
        },
        {
          "name": "Phentermine",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Naltrexone",
          "type": "DRUG"
        },
        {
          "name": "Mirabegron 50mg",
          "type": "DRUG"
        },
        {
          "name": "Mirabegron 200mg",
          "type": "DRUG"
        },
        {
          "name": "Placebo Cohort 1",
          "type": "DRUG"
        },
        {
          "name": "Placebo Cohort 2",
          "type": "DRUG"
        },
        {
          "name": "Placebo for Mirabegron",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "MALE",
        "summary": "18 Years to 35 Years · Male only"
      },
      "enrollment_count": 47,
      "start_date": "2014-02-07",
      "completion_date": "2024-06-11",
      "has_results": true,
      "last_update_posted_date": "2024-10-16",
      "last_synced_at": "2026-09-14T07:24:29.444Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01950520"
    },
    {
      "nct_id": "NCT02135965",
      "title": "Testing Potential Synergistic Effects of Albuterol and Caffeine on Metabolic Rate",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Healthy Volunteers"
      ],
      "interventions": [
        {
          "name": "2mg of Albuterol",
          "type": "DRUG"
        },
        {
          "name": "4mg of Albuterol",
          "type": "DRUG"
        },
        {
          "name": "100mg of Caffeine",
          "type": "DRUG"
        },
        {
          "name": "200mg of Caffeine",
          "type": "DRUG"
        },
        {
          "name": "Albuterol 2mg & Caffeine 100mg",
          "type": "DRUG"
        },
        {
          "name": "Albuterol 2mg and Caffeine 200mg",
          "type": "DRUG"
        },
        {
          "name": "Albuterol 4mg and Caffeine 100mg",
          "type": "DRUG"
        },
        {
          "name": "Albuterol 4mg and Caffeine 200mg",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Pennington Biomedical Research Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 8,
      "start_date": "2009-04",
      "completion_date": "2011-08",
      "has_results": false,
      "last_update_posted_date": "2015-12-18",
      "last_synced_at": "2026-09-14T07:24:29.444Z",
      "location_count": 1,
      "location_summary": "Baton Rouge, Louisiana",
      "locations": [
        {
          "city": "Baton Rouge",
          "state": "Louisiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02135965"
    },
    {
      "nct_id": "NCT06721793",
      "title": "The Impact of a Caffeinated Sports Drink on Performance",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dehydration",
        "Dehydration Related to Exercise"
      ],
      "interventions": [
        {
          "name": "carbohydrate electrolyte drink",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "no-sugar electrolyte drink",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Caffeinated Carbohydrate and electrolyte drink",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Water (Placebo)",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Arizona State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 26,
      "start_date": "2025-12-12",
      "completion_date": "2025-12-16",
      "has_results": false,
      "last_update_posted_date": "2026-01-27",
      "last_synced_at": "2026-09-14T07:24:29.444Z",
      "location_count": 1,
      "location_summary": "Phoenix, Arizona",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06721793"
    },
    {
      "nct_id": "NCT06117280",
      "title": "Effect of Different Dosages of Paraxanthine, the Major Caffeine Metabolite, on Energy and Focus",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Energy",
        "Focus",
        "Caffeine Withdrawal"
      ],
      "interventions": [
        {
          "name": "Paraxanthine 200 mg",
          "type": "OTHER"
        },
        {
          "name": "Paraxanthine 300 mg",
          "type": "OTHER"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Iovate Health Sciences International Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "18 Years to 35 Years"
      },
      "enrollment_count": 45,
      "start_date": "2023-07-18",
      "completion_date": "2023-10-20",
      "has_results": false,
      "last_update_posted_date": "2023-11-07",
      "last_synced_at": "2026-09-14T07:24:29.444Z",
      "location_count": 1,
      "location_summary": "Santa Monica, California",
      "locations": [
        {
          "city": "Santa Monica",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06117280"
    },
    {
      "nct_id": "NCT02180048",
      "title": "\"The Effects of Caffeine on Overactive Bladder Symptoms and Mental Health in Postmenopausal Women\"",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Overactive Bladder",
        "Caffeine",
        "Menopause"
      ],
      "interventions": [
        {
          "name": "400 mg of caffeine/day (Two 200mg pills/day)",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "200 mg of caffeine/day (One 200mg pill and one placebo pill)",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Two placebo pills/day",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Loma Linda University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "58 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "58 Years and older · Female only"
      },
      "enrollment_count": 55,
      "start_date": "2014-07",
      "completion_date": "2018-09-20",
      "has_results": false,
      "last_update_posted_date": "2018-10-25",
      "last_synced_at": "2026-09-14T07:24:29.444Z",
      "location_count": 1,
      "location_summary": "Loma Linda, California",
      "locations": [
        {
          "city": "Loma Linda",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02180048"
    },
    {
      "nct_id": "NCT01435837",
      "title": "Interaction of Caffeine and Hydration on Voice",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Voice Disorders"
      ],
      "interventions": [
        {
          "name": "C2 (200mg of caffeine; 1/2 L of water)",
          "type": "DRUG"
        },
        {
          "name": "C3(200mg of caffeine; 1 L of water)",
          "type": "DRUG"
        },
        {
          "name": "C1 (200mg of caffeine, no water)",
          "type": "DRUG"
        },
        {
          "name": "Placebo (no caffeine, no water).",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Southern Illinois University Carbondale",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "18 Years to 35 Years"
      },
      "enrollment_count": 80,
      "start_date": "2010-10",
      "completion_date": "2013-05",
      "has_results": false,
      "last_update_posted_date": "2013-06-11",
      "last_synced_at": "2026-09-14T07:24:29.444Z",
      "location_count": 1,
      "location_summary": "Carbondale, Illinois",
      "locations": [
        {
          "city": "Carbondale",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01435837"
    },
    {
      "nct_id": "NCT02770105",
      "title": "Theanine and Caffeine on Neurophysiology of Attention",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "L-theanine"
      ],
      "interventions": [
        {
          "name": "Theanine",
          "type": "OTHER"
        },
        {
          "name": "Caffeine",
          "type": "OTHER"
        },
        {
          "name": "Theanine-Caffeine Combination",
          "type": "OTHER"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Texas Tech University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "MALE",
        "summary": "18 Years to 60 Years · Male only"
      },
      "enrollment_count": 9,
      "start_date": "2016-05",
      "completion_date": "2016-06",
      "has_results": false,
      "last_update_posted_date": "2016-09-02",
      "last_synced_at": "2026-09-14T07:24:29.444Z",
      "location_count": 1,
      "location_summary": "Lubbock, Texas",
      "locations": [
        {
          "city": "Lubbock",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02770105"
    }
  ]
}