{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=6%25+CO2%2C+6%25O2%2C+balance+N2",
    "query": {
      "intervention": "6% CO2, 6%O2, balance N2"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 3,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-26T17:20:53.153Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04134754",
      "title": "Carbon Dioxide (CO2) Chemosensitivity and SUDEP",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Epilepsy",
        "SUDEP"
      ],
      "interventions": [
        {
          "name": "6% Carbon dioxide/50% oxygen/balance nitrogen mixture",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Iowa",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 335,
      "start_date": "2019-12-12",
      "completion_date": "2029-10-01",
      "has_results": false,
      "last_update_posted_date": "2026-06-23",
      "last_synced_at": "2026-09-26T17:20:53.153Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04134754"
    },
    {
      "nct_id": "NCT01925482",
      "title": "Trans-Middle-Ear Mucosal Gas Exchange Project 1, Specific Aim 1",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Middle Ear Gas Exchange"
      ],
      "interventions": [
        {
          "name": "6%CO2, 25%O2, balance N2",
          "type": "DRUG"
        },
        {
          "name": "6% CO2, 0%O2, balance N2",
          "type": "DRUG"
        },
        {
          "name": "20%CO2, 6%O2, balance N2",
          "type": "DRUG"
        },
        {
          "name": "0%CO2, 6%O2, balance N2",
          "type": "DRUG"
        },
        {
          "name": "6% CO2, 6%O2, balance N2",
          "type": "DRUG"
        },
        {
          "name": "6%CO2, 6%O2, 0%N2, balance argon",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Cuneyt M. Alper",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 16,
      "start_date": "2014-05-13",
      "completion_date": "2015-05-19",
      "has_results": false,
      "last_update_posted_date": "2019-02-19",
      "last_synced_at": "2026-09-26T17:20:53.153Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01925482"
    },
    {
      "nct_id": "NCT07135583",
      "title": "Non-Invasive Interventions for Respiratory Recovery in Chronic Spinal Cord Injury",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Spinal Cord Injury, Chronic",
        "Spinal Cord Injury Cervical",
        "Spinal Cord Injury Thoracic",
        "Incomplete Spinal Cord Injury"
      ],
      "interventions": [
        {
          "name": "Active Comparator: Single Intervention 1",
          "type": "OTHER"
        },
        {
          "name": "Active Comparator: Single Intervention 2",
          "type": "OTHER"
        },
        {
          "name": "Respiratory Resistance Exercise",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "OTHER",
        "BEHAVIORAL"
      ],
      "sponsor": "Thomas Jefferson University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 20,
      "start_date": "2025-09-18",
      "completion_date": "2027-08-15",
      "has_results": false,
      "last_update_posted_date": "2026-02-05",
      "last_synced_at": "2026-09-26T17:20:53.153Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07135583"
    }
  ]
}