{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=ACL+reconstruction&page=2",
    "query": {
      "intervention": "ACL reconstruction",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=ACL+reconstruction&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-24T06:01:43.662Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03294759",
      "title": "Bio ACL Reconstruction Amnion Collagen Matrix Wrap and Stem Cells",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "ACL - Anterior Cruciate Ligament Rupture"
      ],
      "interventions": [
        {
          "name": "Bio ACL",
          "type": "OTHER"
        },
        {
          "name": "Control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Andrews Research & Education Foundation",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 40,
      "start_date": "2017-09-06",
      "completion_date": "2024-12-06",
      "has_results": false,
      "last_update_posted_date": "2024-02-21",
      "last_synced_at": "2026-09-24T06:01:43.662Z",
      "location_count": 1,
      "location_summary": "Gulf Breeze, Florida",
      "locations": [
        {
          "city": "Gulf Breeze",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03294759"
    },
    {
      "nct_id": "NCT04101682",
      "title": "Continuous Vs Single Shot Block After ACL",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "ACL Injury"
      ],
      "interventions": [
        {
          "name": "Bupivacaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Northwell Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "16 Years and older"
      },
      "enrollment_count": 9,
      "start_date": "2020-09-25",
      "completion_date": "2022-05-17",
      "has_results": false,
      "last_update_posted_date": "2023-10-18",
      "last_synced_at": "2026-09-24T06:01:43.662Z",
      "location_count": 1,
      "location_summary": "Plainview, New York",
      "locations": [
        {
          "city": "Plainview",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04101682"
    },
    {
      "nct_id": "NCT03552705",
      "title": "The Effects of Tranexamic Acid on Joint Inflammation and Cartilage Health in Anterior Cruciate Ligament Injured Patients",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Anterior Cruciate Ligament Reconstruction"
      ],
      "interventions": [
        {
          "name": "Tranexamic Acid",
          "type": "DRUG"
        },
        {
          "name": "Placebos",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "30 Years",
        "sex": "ALL",
        "summary": "18 Years to 30 Years"
      },
      "enrollment_count": 50,
      "start_date": "2019-08-01",
      "completion_date": "2027-01-14",
      "has_results": false,
      "last_update_posted_date": "2026-02-27",
      "last_synced_at": "2026-09-24T06:01:43.662Z",
      "location_count": 1,
      "location_summary": "Stanford, California",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03552705"
    },
    {
      "nct_id": "NCT03794570",
      "title": "BFR Therapy After ACL Reconstruction",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "ACL Injury",
        "Quadriceps Muscle Atrophy"
      ],
      "interventions": [
        {
          "name": "Blood flow restriction therapy - with Delfi Personalized Tourniquet System",
          "type": "DEVICE"
        },
        {
          "name": "Sham blood flow restriction therapy - with Delfi Personalized Tourniquet System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Steadman Philippon Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "14 Years to 70 Years"
      },
      "enrollment_count": 0,
      "start_date": "2018-12-18",
      "completion_date": "2019-06-01",
      "has_results": false,
      "last_update_posted_date": "2019-12-04",
      "last_synced_at": "2026-09-24T06:01:43.662Z",
      "location_count": 1,
      "location_summary": "Vail, Colorado",
      "locations": [
        {
          "city": "Vail",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03794570"
    },
    {
      "nct_id": "NCT06975306",
      "title": "Radiographic Findings and Clinical Outcomes After Bone Grafting Patellar Defect in ACL Reconstruction",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Bone Graft; Complications",
        "ACL Injuries"
      ],
      "interventions": [
        {
          "name": "autologous bone grafts",
          "type": "PROCEDURE"
        },
        {
          "name": "Demineralized bone matrix (DBM)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "OTHER"
      ],
      "sponsor": "University of Arizona",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 75,
      "start_date": "2025-02-11",
      "completion_date": "2027-04-30",
      "has_results": false,
      "last_update_posted_date": "2026-08-14",
      "last_synced_at": "2026-09-24T06:01:43.662Z",
      "location_count": 3,
      "location_summary": "Phoenix, Arizona • Scottsdale, Arizona",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Scottsdale",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06975306"
    },
    {
      "nct_id": "NCT03506685",
      "title": "Effectiveness of Dry Needling and STM on Pain Management for Anterior Cruciate Ligament Reconstruction (ACLR)",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pain and Anterior Cruciate Ligament Reconstruction"
      ],
      "interventions": [
        {
          "name": "Dry needling and STM",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Keller Army Community Hospital",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 0,
      "start_date": "2018-06-01",
      "completion_date": "2019-06-01",
      "has_results": false,
      "last_update_posted_date": "2025-09-23",
      "last_synced_at": "2026-09-24T06:01:43.662Z",
      "location_count": 1,
      "location_summary": "West Point, New York",
      "locations": [
        {
          "city": "West Point",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03506685"
    },
    {
      "nct_id": "NCT04528992",
      "title": "Effects of Blood Flow Restriction (BFR) Therapy on ACL Graft Maturation",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Knee Injuries",
        "Anterior Cruciate Ligament Injuries"
      ],
      "interventions": [
        {
          "name": "Blood Flow Restriction Therapy",
          "type": "OTHER"
        },
        {
          "name": "Standard Postoperative Physical Therapy",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2024-09-20",
      "completion_date": "2024-09-20",
      "has_results": false,
      "last_update_posted_date": "2024-11-25",
      "last_synced_at": "2026-09-24T06:01:43.662Z",
      "location_count": 1,
      "location_summary": "Redwood City, California",
      "locations": [
        {
          "city": "Redwood City",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04528992"
    },
    {
      "nct_id": "NCT04998656",
      "title": "Werewolf Flow 50 During ACL Reconstruction",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anterior Cruciate Ligament Injuries",
        "Anterior Cruciate Ligament Rupture",
        "Anterior Cruciate Ligament Tear",
        "Arthrofibrosis of Knee"
      ],
      "interventions": [
        {
          "name": "Werewolf FLOW 50",
          "type": "DEVICE"
        },
        {
          "name": "Control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "12 Years to 18 Years"
      },
      "enrollment_count": 182,
      "start_date": "2021-07-12",
      "completion_date": "2024-11-02",
      "has_results": true,
      "last_update_posted_date": "2026-09-14",
      "last_synced_at": "2026-09-24T06:01:43.662Z",
      "location_count": 3,
      "location_summary": "Aurora, Colorado • Broomfield, Colorado • Highlands Ranch, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Broomfield",
          "state": "Colorado"
        },
        {
          "city": "Highlands Ranch",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04998656"
    },
    {
      "nct_id": "NCT01068275",
      "title": "Lumbar Plexus Catheter Versus Femoral Nerve Catheter for Postoperative Pain After Anterior Cruciate Ligament (ACL) Repair",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Postoperative Pain"
      ],
      "interventions": [
        {
          "name": "lumbar plexus catheter",
          "type": "PROCEDURE"
        },
        {
          "name": "femoral nerve catheter",
          "type": "PROCEDURE"
        },
        {
          "name": "single-shot femoral block",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Seattle Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "11 Years",
        "maximum_age": "21 Years",
        "sex": "ALL",
        "summary": "11 Years to 21 Years"
      },
      "enrollment_count": 114,
      "start_date": "2010-04",
      "completion_date": "2012-09",
      "has_results": false,
      "last_update_posted_date": "2010-08-26",
      "last_synced_at": "2026-09-24T06:01:43.662Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01068275"
    },
    {
      "nct_id": "NCT03841500",
      "title": "Prospective Evaluation of Osseous Integration in ACL Reconstruction Comparing Tightrope vs Interference Screw Fixation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "ACL - Anterior Cruciate Ligament Rupture"
      ],
      "interventions": [
        {
          "name": "Biocomposite intereference screw femoral tunnel fixation",
          "type": "DEVICE"
        },
        {
          "name": "Endobutton (Tightrope) femoral tunnel fixation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Kelsey-Seybold Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 37,
      "start_date": "2016-01",
      "completion_date": "2017-01",
      "has_results": false,
      "last_update_posted_date": "2019-02-15",
      "last_synced_at": "2026-09-24T06:01:43.662Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03841500"
    }
  ]
}