{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=AFO",
    "query": {
      "intervention": "AFO"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 39,
    "total_pages": 4,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=AFO&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-07T09:05:19.641Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07721792",
      "title": "IM ABLE 2: Injuries Managed With Advanced Bracing for Lower Extremities",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lower Limb Injury",
        "Ankle Foot Orthosis (AFO)",
        "Lower Limb Trauma"
      ],
      "interventions": [
        {
          "name": "Advanced Ankle Foot Orthosis (AFO)",
          "type": "DEVICE"
        },
        {
          "name": "Conventional Ankle Foot Orthosis (AFO)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of South Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 75,
      "start_date": "2026-07-31",
      "completion_date": "2029-01-31",
      "has_results": false,
      "last_update_posted_date": "2026-07-23",
      "last_synced_at": "2026-09-07T09:05:19.641Z",
      "location_count": 3,
      "location_summary": "Tampa, Florida • New York, New York",
      "locations": [
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07721792"
    },
    {
      "nct_id": "NCT03901053",
      "title": "Ankle Foot Orthosis Comparative Effect",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Foot Injuries and Disorders"
      ],
      "interventions": [
        {
          "name": "Reaktiv AFO",
          "type": "DEVICE"
        },
        {
          "name": "PhatBrace AFO",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Jason Wilken",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 54,
      "start_date": "2020-02-27",
      "completion_date": "2023-12-18",
      "has_results": true,
      "last_update_posted_date": "2026-01-29",
      "last_synced_at": "2026-09-07T09:05:19.641Z",
      "location_count": 3,
      "location_summary": "Iowa City, Iowa • Bethesda, Maryland • Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        },
        {
          "city": "Bethesda",
          "state": "Maryland"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03901053"
    },
    {
      "nct_id": "NCT01087957",
      "title": "WalkAide Compared to Ankle-Foot Orthosis (AFO) in Stroke Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Stroke"
      ],
      "interventions": [
        {
          "name": "WalkAide",
          "type": "DEVICE"
        },
        {
          "name": "Ankle-Foot Orthosis (AFO)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Innovative Neurotronics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 495,
      "start_date": "2010-03",
      "completion_date": "2013-06",
      "has_results": true,
      "last_update_posted_date": "2014-05-13",
      "last_synced_at": "2026-09-07T09:05:19.641Z",
      "location_count": 29,
      "location_summary": "Loma Linda, California • Los Angeles, California • Pomona, California + 25 more",
      "locations": [
        {
          "city": "Loma Linda",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Pomona",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Hartford",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01087957"
    },
    {
      "nct_id": "NCT06127264",
      "title": "Reliability of Force Measurement Within the Carbon Fiber Orthosis Proximal Cuff",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy",
        "Ankle Foot Orthosis (AFO)",
        "Peripheral Neuropathy"
      ],
      "interventions": [
        {
          "name": "Carbon Fiber Custom Dynamic Orthosis (CDO)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Iowa",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 60,
      "start_date": "2024-03-01",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-12-31",
      "last_synced_at": "2026-09-07T09:05:19.641Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06127264"
    },
    {
      "nct_id": "NCT01208142",
      "title": "Toe Walker Gait Trial",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Gait"
      ],
      "interventions": [
        {
          "name": "standard of care treatment",
          "type": "OTHER"
        },
        {
          "name": "Ankle Flexion Dynasplint",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DEVICE"
      ],
      "sponsor": "Dynasplint Systems, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Year",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "1 Year to 18 Years"
      },
      "enrollment_count": 10,
      "start_date": "2010-09",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2013-08-12",
      "last_synced_at": "2026-09-07T09:05:19.641Z",
      "location_count": 2,
      "location_summary": "Columbus, Ohio • Lubbock, Texas",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        },
        {
          "city": "Lubbock",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01208142"
    },
    {
      "nct_id": "NCT01001390",
      "title": "The Effects of Ankle Foot Orthoses on Gait Efficiency in Children With Acute Lymphoblastic Leukemia and Foot Drop",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Foot Drop",
        "Acute Lymphoblastic Leukemia"
      ],
      "interventions": [
        {
          "name": "AFO Device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "St. Jude Children's Research Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "6 Years to 18 Years"
      },
      "enrollment_count": 2,
      "start_date": "2009-10",
      "completion_date": "2011-06",
      "has_results": true,
      "last_update_posted_date": "2014-03-27",
      "last_synced_at": "2026-09-07T09:05:19.641Z",
      "location_count": 1,
      "location_summary": "Memphis, Tennessee",
      "locations": [
        {
          "city": "Memphis",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01001390"
    },
    {
      "nct_id": "NCT06127316",
      "title": "The Effects of Heel Distraction Height on Foot Loading With Carbon Fiber Custom Dynamic Orthoses",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Traumatic Lower Limb Injury"
      ],
      "interventions": [
        {
          "name": "Carbon Fiber Custom Dynamic Orthosis (CDO)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Iowa",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 20,
      "start_date": "2024-08-16",
      "completion_date": "2026-06-01",
      "has_results": false,
      "last_update_posted_date": "2026-01-15",
      "last_synced_at": "2026-09-07T09:05:19.641Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06127316"
    },
    {
      "nct_id": "NCT02693834",
      "title": "Effects of Two Different Types of Ankle Foot Orthoses on Gait Outcomes in Patients With Subacute Stroke.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Stroke",
        "CVA",
        "Hemiplegia",
        "Hemiparesis",
        "Foot Drop"
      ],
      "interventions": [
        {
          "name": "Posterior Leaf spring AFO",
          "type": "DEVICE"
        },
        {
          "name": "Double adjustable AFO",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Texas Woman's University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 23,
      "start_date": "2016-01",
      "completion_date": "2018-04",
      "has_results": true,
      "last_update_posted_date": "2020-02-28",
      "last_synced_at": "2026-09-07T09:05:19.641Z",
      "location_count": 1,
      "location_summary": "Frisco, Texas",
      "locations": [
        {
          "city": "Frisco",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02693834"
    },
    {
      "nct_id": "NCT01798927",
      "title": "Effect of Lower Extremity Ankle Foot Orthoses in Parkinson's Disease",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Parkinson's Disease"
      ],
      "interventions": [
        {
          "name": "Ankle foot orthosis",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "50 Years to 75 Years"
      },
      "enrollment_count": 4,
      "start_date": "2012-12",
      "completion_date": "2013-07",
      "has_results": true,
      "last_update_posted_date": "2015-08-03",
      "last_synced_at": "2026-09-07T09:05:19.641Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01798927"
    },
    {
      "nct_id": "NCT06692686",
      "title": "AFO Prescription to Optimize Post-Stroke Function",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ankle Foot Orthosis (AFO)",
        "Stroke Patients",
        "Post-Stroke Hemiparesis"
      ],
      "interventions": [
        {
          "name": "Pre-fabricated (PF) ankle-foot orthosis (AFO)",
          "type": "DEVICE"
        },
        {
          "name": "Carbon-strut (CS) ankle-foot orthosis (AFO)",
          "type": "DEVICE"
        },
        {
          "name": "Multifunctional articulating (MA) ankle-foot orthosis (AFO)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Texas at Austin",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 120,
      "start_date": "2025-07-08",
      "completion_date": "2027-10",
      "has_results": false,
      "last_update_posted_date": "2025-08-21",
      "last_synced_at": "2026-09-07T09:05:19.641Z",
      "location_count": 4,
      "location_summary": "Downey, California • Jacksonville, Florida • Charleston, South Carolina + 1 more",
      "locations": [
        {
          "city": "Downey",
          "state": "California"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Charleston",
          "state": "South Carolina"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06692686"
    }
  ]
}