{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Active+Mask&page=13", "query": { "intervention": "Active Mask", "page": 13 }, "page_size": 10 }, "pagination": { "page": 13, "page_size": 10, "total_count": 354, "total_pages": 36, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Active+Mask&page=14&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Active+Mask&page=12&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-23T12:33:01.735Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT04123626", "title": "A Study to Evaluate the Safety and Tolerability of QR-1123 in Subjects With Autosomal Dominant Retinitis Pigmentosa Due to the P23H Mutation in the RHO Gene", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Autosomal Dominant Retinitis Pigmentosa", "Eye Diseases", "Eye Diseases, Hereditary", "Retinal Dystrophies", "Retinal Disease", "Retinitis", "Vision Tunnel", "Vision Disorders" ], "interventions": [ { "name": "QR-1123", "type": "DRUG" }, { "name": "Sham procedure", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "ProQR Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 11, "start_date": "2019-10-07", "completion_date": "2022-06-07", "has_results": false, "last_update_posted_date": "2022-05-06", "last_synced_at": "2026-10-23T12:33:01.735Z", "location_count": 5, "location_summary": "Aurora, Colorado • Gainesville, Florida • Lexington, Kentucky + 2 more", "locations": [ { "city": "Aurora", "state": "Colorado" }, { "city": "Gainesville", "state": "Florida" }, { "city": "Lexington", "state": "Kentucky" }, { "city": "Portland", "state": "Oregon" }, { "city": "Dallas", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT04123626" }, { "nct_id": "NCT02867735", "title": "A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamic Activity of Intravitreal LKA651 in Patients With Macular Edema", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Macular Edema", "Diabetic Macular Edema", "Neovascular Age-related Macular Degeneration", "Retinal Vein Occlusions" ], "interventions": [ { "name": "LKA651", "type": "DRUG" }, { "name": "Sham Comparator", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Novartis Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "18 Years to 85 Years" }, "enrollment_count": 28, "start_date": "2016-09-21", "completion_date": "2018-02-15", "has_results": false, "last_update_posted_date": "2022-04-15", "last_synced_at": "2026-10-23T12:33:01.735Z", "location_count": 5, "location_summary": "Pasadena, California • Fort Myers, Florida • Miami, Florida + 2 more", "locations": [ { "city": "Pasadena", "state": "California" }, { "city": "Fort Myers", "state": "Florida" }, { "city": "Miami", "state": "Florida" }, { "city": "Winter Haven", "state": "Florida" }, { "city": "Augusta", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT02867735" }, { "nct_id": "NCT06153342", "title": "A Study of TL-925 for the Treatment of Allergic Conjunctivitis", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Allergic Conjunctivitis" ], "interventions": [ { "name": "TL-925", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Telios Pharma, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 70, "start_date": "2023-11", "completion_date": "2024-01", "has_results": false, "last_update_posted_date": "2023-12-01", "last_synced_at": "2026-10-23T12:33:01.735Z", "location_count": 1, "location_summary": "Andover, Massachusetts", "locations": [ { "city": "Andover", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT06153342" }, { "nct_id": "NCT02302079", "title": "A Study to Evaluate ASP8232 in Reducing Central Retinal Thickness in Subjects With Diabetic Macular Edema (DME)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Diabetes Mellitus", "Diabetic Macular Edema" ], "interventions": [ { "name": "ASP8232", "type": "DRUG" }, { "name": "ranibizumab", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Sham intravitreal (IVT) injection", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Astellas Pharma Europe B.V.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "18 Years to 85 Years" }, "enrollment_count": 96, "start_date": "2015-01-12", "completion_date": "2016-08-12", "has_results": false, "last_update_posted_date": "2024-10-31", "last_synced_at": "2026-10-23T12:33:01.735Z", "location_count": 21, "location_summary": "Phoenix, Arizona • Tucson, Arizona • Arcadia, California + 18 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Arcadia", "state": "California" }, { "city": "Beverly Hills", "state": "California" }, { "city": "Palm Desert", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02302079" }, { "nct_id": "NCT04429503", "title": "Study of a High-Dose Aflibercept in Participants With Diabetic Eye Disease", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Diabetic Macular Edema", "Type 1 Diabetes Mellitus", "Type 2 Diabetes Mellitus" ], "interventions": [ { "name": "aflibercept", "type": "DRUG" }, { "name": "High-dose aflibercept", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Regeneron Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 660, "start_date": "2020-06-29", "completion_date": "2024-06-18", "has_results": true, "last_update_posted_date": "2025-08-08", "last_synced_at": "2026-10-23T12:33:01.735Z", "location_count": 84, "location_summary": "Phoenix, Arizona • Arcadia, California • Beverly Hills, California + 78 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Arcadia", "state": "California" }, { "city": "Beverly Hills", "state": "California" }, { "city": "Campbell", "state": "California" }, { "city": "Encino", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04429503" }, { "nct_id": "NCT06437301", "title": "End Tidal CO2 and Masks: Is There a Correlation?", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Hypercapnia" ], "interventions": [ { "name": "Baseline measure of ETCO2 without mask", "type": "OTHER" }, { "name": "Baseline ETCO2 with mask", "type": "OTHER" }, { "name": "ETCO2 after 200 meter walk with mask", "type": "OTHER" }, { "name": "ETCO2 after 200 meter walk without mask", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "CHRISTUS Health", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 31, "start_date": "2021-07-01", "completion_date": "2022-03-16", "has_results": false, "last_update_posted_date": "2024-09-19", "last_synced_at": "2026-10-23T12:33:01.735Z", "location_count": 1, "location_summary": "Corpus Christi, Texas", "locations": [ { "city": "Corpus Christi", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT06437301" }, { "nct_id": "NCT07128628", "title": "A Study Evaluating the Safety and Efficacy of a Fixed-Dose Combination for Dry Eye Disease", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Dry Eye Disease" ], "interventions": [ { "name": "Lifitegrast/Perfluorohexyloctane Fixed Dose Combination", "type": "DRUG" }, { "name": "Lifitegrast", "type": "DRUG" }, { "name": "Perfluorohexyloctane", "type": "DRUG" }, { "name": "Vehicle", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Bausch & Lomb Incorporated", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 443, "start_date": "2025-10-24", "completion_date": "2026-05-28", "has_results": false, "last_update_posted_date": "2026-07-14", "last_synced_at": "2026-10-23T12:33:01.735Z", "location_count": 32, "location_summary": "Phoenix, Arizona • Glendale, California • Long Beach, California + 27 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Glendale", "state": "California" }, { "city": "Long Beach", "state": "California" }, { "city": "Murrieta", "state": "California" }, { "city": "Newport Beach", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT07128628" }, { "nct_id": "NCT00344721", "title": "A Placebo Controlled Double Masked Clinical Assessment Study of Essential Fatty Acid Supplement and Its Effect on Patients With Apparent Aqueous Deficient Dry Eye Syndrome", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Dry Eye Syndrome" ], "interventions": [ { "name": "Omega-3 fatty acid supplement", "type": "DIETARY_SUPPLEMENT" }, { "name": "Placebo", "type": "DIETARY_SUPPLEMENT" } ], "intervention_types": [ "DIETARY_SUPPLEMENT" ], "sponsor": "University of Texas Southwestern Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "90 Years", "sex": "ALL", "summary": "18 Years to 90 Years" }, "enrollment_count": 42, "start_date": "2004-09", "completion_date": "2008-10", "has_results": false, "last_update_posted_date": "2018-05-14", "last_synced_at": "2026-10-23T12:33:01.735Z", "location_count": 1, "location_summary": "Dallas, Texas", "locations": [ { "city": "Dallas", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00344721" }, { "nct_id": "NCT07007065", "title": "Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity of Surabgene Lomparvovec in Adult Participants With Neovascular Age-Related Macular Degeneration (nAMD)", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Neovascular Age-related Macular Degeneration" ], "interventions": [ { "name": "Surabgene Lomparvovec (ABBV-RGX-314)", "type": "DRUG" }, { "name": "Ranibizumab Control", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "AbbVie", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "50 Years", "maximum_age": null, "sex": "ALL", "summary": "50 Years and older" }, "enrollment_count": 561, "start_date": "2025-11-05", "completion_date": "2033-03", "has_results": false, "last_update_posted_date": "2026-10-23", "last_synced_at": "2026-10-23T12:33:01.735Z", "location_count": 55, "location_summary": "Mesa, Arizona • Sun City, Arizona • Campbell, California + 51 more", "locations": [ { "city": "Mesa", "state": "Arizona" }, { "city": "Sun City", "state": "Arizona" }, { "city": "Campbell", "state": "California" }, { "city": "Encino", "state": "California" }, { "city": "Huntington Beach", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT07007065" }, { "nct_id": "NCT06587113", "title": "An Investigation of Attentional and Inhibitory Processes During Active Visual Search in Humans", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Eye Movements", "Attention", "Executive Function" ], "interventions": [ { "name": "Contour Search Task", "type": "OTHER" }, { "name": "Stop signal Task", "type": "BEHAVIORAL" }, { "name": "Useful field of View", "type": "BEHAVIORAL" }, { "name": "Attentional capture search task", "type": "BEHAVIORAL" } ], "intervention_types": [ "OTHER", "BEHAVIORAL" ], "sponsor": "University of Colorado, Denver", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 225, "start_date": "2024-09-15", "completion_date": "2026-05-15", "has_results": false, "last_update_posted_date": "2026-02-20", "last_synced_at": "2026-10-23T12:33:01.735Z", "location_count": 1, "location_summary": "Denver, Colorado", "locations": [ { "city": "Denver", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT06587113" } ] }