{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Active+lozenge",
    "query": {
      "intervention": "Active lozenge"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 33,
    "total_pages": 4,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Active+lozenge&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-04T19:28:53.063Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00332644",
      "title": "Smoking Cessation Medications: Efficacy, Mechanisms and Algorithms",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Nicotine Dependence"
      ],
      "interventions": [
        {
          "name": "nicotine patch",
          "type": "DRUG"
        },
        {
          "name": "nicotine lozenge",
          "type": "DRUG"
        },
        {
          "name": "nicotine patch + nicotine lozenge",
          "type": "DRUG"
        },
        {
          "name": "bupropion",
          "type": "DRUG"
        },
        {
          "name": "bupropion + lozenge",
          "type": "DRUG"
        },
        {
          "name": "placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1504,
      "start_date": "2004-09",
      "completion_date": "2010-08",
      "has_results": true,
      "last_update_posted_date": "2011-11-30",
      "last_synced_at": "2026-09-04T19:28:53.063Z",
      "location_count": 2,
      "location_summary": "Madison, Wisconsin • Milwaukee, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        },
        {
          "city": "Milwaukee",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00332644"
    },
    {
      "nct_id": "NCT02252770",
      "title": "Nitric Oxide Supplementation in Argininosuccinic Aciduria",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Argininosuccinic Aciduria",
        "Argininosuccinate Lyase Deficiency",
        "Urea Cycle Disorders"
      ],
      "interventions": [
        {
          "name": "Nitric oxide supplement",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Baylor College of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "8 Years to 64 Years"
      },
      "enrollment_count": 12,
      "start_date": "2014-09",
      "completion_date": "2018-05",
      "has_results": false,
      "last_update_posted_date": "2020-01-18",
      "last_synced_at": "2026-09-04T19:28:53.063Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02252770"
    },
    {
      "nct_id": "NCT05413382",
      "title": "Effect of an Investigational Lozenge (Biofresh® 4plus) Versus Placebo Control on Oral Malodor (Intra-Oral Halitosis)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Halitosis"
      ],
      "interventions": [
        {
          "name": "Biofresh® 4plus",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Novozymes A/S",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 53,
      "start_date": "2021-09-28",
      "completion_date": "2021-12-22",
      "has_results": false,
      "last_update_posted_date": "2022-06-10",
      "last_synced_at": "2026-09-04T19:28:53.063Z",
      "location_count": 1,
      "location_summary": "Fort Wayne, Indiana",
      "locations": [
        {
          "city": "Fort Wayne",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05413382"
    },
    {
      "nct_id": "NCT02050308",
      "title": "Web-based Smoking Cessation Program for Tribal College Students",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Smoking Cessation"
      ],
      "interventions": [
        {
          "name": "Internet-All Nations Breath of Life (I-ANBL)",
          "type": "OTHER"
        },
        {
          "name": "Honoring the Gift of Heart Health",
          "type": "OTHER"
        },
        {
          "name": "Nicotine gum, Patch, or Lozenge or Zyban® or Chantix®",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DRUG"
      ],
      "sponsor": "Won Choi, PhD, MPH",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 251,
      "start_date": "2015-05",
      "completion_date": "2019-03-31",
      "has_results": true,
      "last_update_posted_date": "2021-12-07",
      "last_synced_at": "2026-09-04T19:28:53.063Z",
      "location_count": 2,
      "location_summary": "Kansas City, Kansas • Pablo, Montana",
      "locations": [
        {
          "city": "Kansas City",
          "state": "Kansas"
        },
        {
          "city": "Pablo",
          "state": "Montana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02050308"
    },
    {
      "nct_id": "NCT05365633",
      "title": "Empowering LGBTQ+ Tobacco Cessation Pilot",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoking Cessation"
      ],
      "interventions": [
        {
          "name": "Empowerment activity-enhanced tobacco cessation assistance",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Oklahoma",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2022-08-01",
      "completion_date": "2024-01-11",
      "has_results": true,
      "last_update_posted_date": "2025-05-15",
      "last_synced_at": "2026-09-04T19:28:53.063Z",
      "location_count": 1,
      "location_summary": "Oklahoma City, Oklahoma",
      "locations": [
        {
          "city": "Oklahoma City",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05365633"
    },
    {
      "nct_id": "NCT01341938",
      "title": "Nicotine Lozenges and Assisted Self-help for Smokeless Tobacco Cessation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smokeless Tobacco Cessation"
      ],
      "interventions": [
        {
          "name": "Commit® nicotine lozenges (4 mg) & self-help materials",
          "type": "DRUG"
        },
        {
          "name": "Commit® nicotine lozenges (4 mg) & phone counseling & self-help materials",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Phone counseling & self-help materials",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "Oregon Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1067,
      "start_date": "2011-07",
      "completion_date": "2012-11",
      "has_results": false,
      "last_update_posted_date": "2021-08-04",
      "last_synced_at": "2026-09-04T19:28:53.063Z",
      "location_count": 1,
      "location_summary": "Eugene, Oregon",
      "locations": [
        {
          "city": "Eugene",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01341938"
    },
    {
      "nct_id": "NCT04358705",
      "title": "C-FLASH (Cigarillo Flavor and Abuse Liability, Attention, and Substitution in youtH)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoking Behaviors"
      ],
      "interventions": [
        {
          "name": "Aim 1: Online survey",
          "type": "OTHER"
        },
        {
          "name": "Eye Tracking Activity",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Eye tracking survey",
          "type": "OTHER"
        },
        {
          "name": "Online Experimental Marketplace (ETM)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Aim 3 survey",
          "type": "OTHER"
        },
        {
          "name": "Cognitive Interviews",
          "type": "OTHER"
        },
        {
          "name": "Supplemental Aim 1 Interviews",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER",
        "BEHAVIORAL"
      ],
      "sponsor": "Case Comprehensive Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": "28 Years",
        "sex": "ALL",
        "summary": "16 Years to 28 Years"
      },
      "enrollment_count": 658,
      "start_date": "2020-05-29",
      "completion_date": "2023-02-10",
      "has_results": false,
      "last_update_posted_date": "2024-03-06",
      "last_synced_at": "2026-09-04T19:28:53.063Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04358705"
    },
    {
      "nct_id": "NCT05136430",
      "title": "A Multiple Health Behavior Change Intervention for Overweight and Obese Smokers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoking Cessation",
        "Obesity"
      ],
      "interventions": [
        {
          "name": "Self-Regulation strategies + large changes (SR)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Healthy Lifestyle Education (LE)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Smoking Cessation Treatment",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "Brown University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 55,
      "start_date": "2021-11-01",
      "completion_date": "2024-01-10",
      "has_results": true,
      "last_update_posted_date": "2025-05-09",
      "last_synced_at": "2026-09-04T19:28:53.063Z",
      "location_count": 1,
      "location_summary": "Providence, Rhode Island",
      "locations": [
        {
          "city": "Providence",
          "state": "Rhode Island"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05136430"
    },
    {
      "nct_id": "NCT01048866",
      "title": "A Study of Flurbiprofen 8.75 mg Lozenge in Patients With Pharyngitis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Pharyngitis"
      ],
      "interventions": [
        {
          "name": "placebo",
          "type": "DRUG"
        },
        {
          "name": "flurbiprofen",
          "type": "DRUG"
        },
        {
          "name": "acetaminophen 650mg",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Reckitt Benckiser LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 198,
      "start_date": "2009-11",
      "completion_date": "2011-03",
      "has_results": true,
      "last_update_posted_date": "2017-09-21",
      "last_synced_at": "2026-09-04T19:28:53.063Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01048866"
    },
    {
      "nct_id": "NCT03235466",
      "title": "A Prospective Trial of Behavioral Therapy for Chronic Cough",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cough"
      ],
      "interventions": [
        {
          "name": "Voice Therapy",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Voice Therapy and Heart Rate Variability Biofeedback",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Heart Rate Variability Biofeedback",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of California, San Diego",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 45,
      "start_date": "2018-02-01",
      "completion_date": "2021-12-01",
      "has_results": false,
      "last_update_posted_date": "2020-12-04",
      "last_synced_at": "2026-09-04T19:28:53.063Z",
      "location_count": 1,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03235466"
    }
  ]
}