{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Active+then+Sham+Treatment&page=30", "query": { "intervention": "Active then Sham Treatment", "page": 30 }, "page_size": 10 }, "pagination": { "page": 30, "page_size": 10, "total_count": 757, "total_pages": 76, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Active+then+Sham+Treatment&page=31&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Active+then+Sham+Treatment&page=29&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-15T17:55:22.549Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT01931059", "title": "Acute D2 Receptor Blockade Induced Neuronal Network Changes in Human Volunteers", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Imaging of the Brain and Antipsychotics", "Neuronal Network Changes" ], "interventions": [ { "name": "Risperidone", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Northwell Health", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "60 Years", "sex": "ALL", "summary": "18 Years to 60 Years" }, "enrollment_count": 11, "start_date": "2013-07", "completion_date": "2016-07", "has_results": true, "last_update_posted_date": "2018-04-30", "last_synced_at": "2026-10-15T17:55:22.549Z", "location_count": 1, "location_summary": "Glen Oaks, New York", "locations": [ { "city": "Glen Oaks", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT01931059" }, { "nct_id": "NCT01264770", "title": "Evaluation of Efficacy and Safety of Fostamatinib Monotherapy Compared With Adalimumab Monotherapy in Patients With Rheumatoid Arthritis (RA)", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Rheumatoid Arthritis" ], "interventions": [ { "name": "Fostamatinib and placebo injections", "type": "DRUG" }, { "name": "Adalimumab and placebo of fostamatinib", "type": "DRUG" }, { "name": "Placebo of fostamatinib, fostamatinib, and placebo injections", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "AstraZeneca", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 644, "start_date": "2011-01", "completion_date": "2013-08", "has_results": true, "last_update_posted_date": "2014-05-06", "last_synced_at": "2026-10-15T17:55:22.549Z", "location_count": 40, "location_summary": "Birmingham, Alabama • Glendale, Arizona • Mesa, Arizona + 37 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Glendale", "state": "Arizona" }, { "city": "Mesa", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Scottsdale", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT01264770" }, { "nct_id": "NCT05343533", "title": "Probiotic Administration on Mood", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Depression", "Sleep", "Stress", "Anxiety", "Mood Disorders" ], "interventions": [ { "name": "Probiotic", "type": "DIETARY_SUPPLEMENT" } ], "intervention_types": [ "DIETARY_SUPPLEMENT" ], "sponsor": "Lindenwood University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "50 Years", "sex": "ALL", "summary": "18 Years to 50 Years" }, "enrollment_count": 70, "start_date": "2019-07-17", "completion_date": "2022-01-01", "has_results": false, "last_update_posted_date": "2022-04-25", "last_synced_at": "2026-10-15T17:55:22.549Z", "location_count": 1, "location_summary": "Saint Charles, Missouri", "locations": [ { "city": "Saint Charles", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT05343533" }, { "nct_id": "NCT04126603", "title": "Impact of Semaglutide on CD34+ EPC and Fat Derived MSC", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Diabetes Mellitus, Type 2" ], "interventions": [ { "name": "Semaglutide", "type": "DRUG" }, { "name": "Placebos", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Sabyasachi Sen", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "20 Years", "maximum_age": "90 Years", "sex": "ALL", "summary": "20 Years to 90 Years" }, "enrollment_count": 10, "start_date": "2019-08-01", "completion_date": "2025-05-14", "has_results": true, "last_update_posted_date": "2025-09-09", "last_synced_at": "2026-10-15T17:55:22.549Z", "location_count": 2, "location_summary": "Washington D.C., District of Columbia", "locations": [ { "city": "Washington D.C.", "state": "District of Columbia" }, { "city": "Washington D.C.", "state": "District of Columbia" } ], "official_url": "https://clinicaltrials.gov/study/NCT04126603" }, { "nct_id": "NCT04605588", "title": "A Triple Combination Antiviral Coronavirus Therapy (TriACT) for COVID-19", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "SARS-CoV Infection", "Covid19" ], "interventions": [ { "name": "Nitazoxanide", "type": "DRUG" }, { "name": "Placebo Nitazoxanide", "type": "DRUG" }, { "name": "Ribavirin", "type": "DRUG" }, { "name": "Placebo Ribavirin", "type": "DRUG" }, { "name": "Hydroxychloroquine", "type": "DRUG" }, { "name": "Placebo Hydroxychloroquine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Rutgers, The State University of New Jersey", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": null, "sex": "ALL", "summary": "21 Years and older" }, "enrollment_count": 7, "start_date": "2020-12-02", "completion_date": "2021-02-04", "has_results": true, "last_update_posted_date": "2022-05-05", "last_synced_at": "2026-10-15T17:55:22.549Z", "location_count": 1, "location_summary": "New Brunswick, New Jersey", "locations": [ { "city": "New Brunswick", "state": "New Jersey" } ], "official_url": "https://clinicaltrials.gov/study/NCT04605588" }, { "nct_id": "NCT05143554", "title": "Auricular Neurostimulation for Chemotherapy Induced Nausea and Vomiting", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Chemotherapy-induced Nausea and Vomiting" ], "interventions": [ { "name": "Auricular percutaneous neurostimulation", "type": "DEVICE" }, { "name": "Sham percutaneous neurostimulation", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Medical College of Wisconsin", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "4 Years", "maximum_age": "30 Years", "sex": "ALL", "summary": "4 Years to 30 Years" }, "enrollment_count": 18, "start_date": "2021-04-29", "completion_date": "2025-09-23", "has_results": false, "last_update_posted_date": "2026-10-09", "last_synced_at": "2026-10-15T17:55:22.549Z", "location_count": 1, "location_summary": "Milwaukee, Wisconsin", "locations": [ { "city": "Milwaukee", "state": "Wisconsin" } ], "official_url": "https://clinicaltrials.gov/study/NCT05143554" }, { "nct_id": "NCT00575822", "title": "A Study to Determine the Effectiveness of Endoscopic Full-Thickness Plication for the Treatment of GERD", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Gastroesophageal Reflux Disease (GERD)" ], "interventions": [ { "name": "NDO Full-thickness Plicator", "type": "DEVICE" }, { "name": "Sham Control", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "NDO Surgical, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 159, "start_date": "2005-01", "completion_date": "2008-03", "has_results": false, "last_update_posted_date": "2008-07-16", "last_synced_at": "2026-10-15T17:55:22.549Z", "location_count": 13, "location_summary": "Orange, California • San Ramon, California • Denver, Colorado + 8 more", "locations": [ { "city": "Orange", "state": "California" }, { "city": "San Ramon", "state": "California" }, { "city": "Denver", "state": "Colorado" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "Omaha", "state": "Nebraska" } ], "official_url": "https://clinicaltrials.gov/study/NCT00575822" }, { "nct_id": "NCT05286762", "title": "Phase 3 Efficacy and Safety Fixed-Dose Study in Pediatrics (6-17) With ADHD Using CTx-1301", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "ADHD", "Attention Deficit Hyperactivity Disorder", "ADHD - Combined Type", "Attention Deficit Hyperactivity Disorder Combined", "Attention-deficit Hyperactivity", "Attention Deficit Hyper Activity" ], "interventions": [ { "name": "CTx-1301-Dexmethylphenidate 12.5 mg (titration only)", "type": "DRUG" }, { "name": "CTx-1301-Dexmethylphenidate 18.75mg (randomized fixed dose)", "type": "DRUG" }, { "name": "CTx-1301-Dexmethylphenidate 25mg (randomized fixed dose)", "type": "DRUG" }, { "name": "CTx-1301-Dexmethylphenidate 37.5 mg (randomized fixed dose)", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Cingulate Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "6 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "6 Years to 17 Years" }, "enrollment_count": 103, "start_date": "2023-08-01", "completion_date": "2024-02-29", "has_results": true, "last_update_posted_date": "2026-01-22", "last_synced_at": "2026-10-15T17:55:22.549Z", "location_count": 24, "location_summary": "Jacksonville, Florida • Maitland, Florida • Orlando, Florida + 21 more", "locations": [ { "city": "Jacksonville", "state": "Florida" }, { "city": "Maitland", "state": "Florida" }, { "city": "Orlando", "state": "Florida" }, { "city": "Atlanta", "state": "Georgia" }, { "city": "Springfield", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT05286762" }, { "nct_id": "NCT06565065", "title": "ImmunoBoost: The Lymphatic Osteopathic Manipulative Treatment Protocol Study", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Healthy" ], "interventions": [ { "name": "Osteopathic Manipulative Treatment (OMT)", "type": "PROCEDURE" }, { "name": "Sham Light Touch", "type": "OTHER" }, { "name": "Exercise Protocol", "type": "OTHER" } ], "intervention_types": [ "PROCEDURE", "OTHER" ], "sponsor": "Western University of Health Sciences", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 30, "start_date": "2025-07-14", "completion_date": "2026-12-30", "has_results": false, "last_update_posted_date": "2026-08-19", "last_synced_at": "2026-10-15T17:55:22.549Z", "location_count": 1, "location_summary": "Pomona, California", "locations": [ { "city": "Pomona", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06565065" }, { "nct_id": "NCT01222247", "title": "Antenatal Late Preterm Steroids (ALPS): A Randomized Placebo-Controlled Trial", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Pregnancy", "Respiratory Distress Syndrome", "Pregnancy Outcomes", "Preterm Birth" ], "interventions": [ { "name": "Betamethasone", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "The George Washington University Biostatistics Center", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "FEMALE", "summary": "Female only" }, "enrollment_count": 2831, "start_date": "2010-10", "completion_date": "2022-08-31", "has_results": true, "last_update_posted_date": "2023-03-28", "last_synced_at": "2026-10-15T17:55:22.549Z", "location_count": 17, "location_summary": "Birmingham, Alabama • Stanford, California • Denver, Colorado + 14 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Stanford", "state": "California" }, { "city": "Denver", "state": "Colorado" }, { "city": "Chicago", "state": "Illinois" }, { "city": "Detroit", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT01222247" } ] }