{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Acyline",
    "query": {
      "intervention": "Acyline"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 16,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Acyline&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-03T04:50:08.233Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00663793",
      "title": "ORAL T-6: Oral Androgens in Man-6",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Contraception",
        "Hypogonadism"
      ],
      "interventions": [
        {
          "name": "Acyline",
          "type": "DRUG"
        },
        {
          "name": "Testosterone",
          "type": "DRUG"
        },
        {
          "name": "Finasteride",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Washington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "MALE",
        "summary": "18 Years to 50 Years · Male only"
      },
      "enrollment_count": 16,
      "start_date": "2008-10",
      "completion_date": "2009-06",
      "has_results": true,
      "last_update_posted_date": "2011-01-24",
      "last_synced_at": "2026-09-03T04:50:08.233Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00663793"
    },
    {
      "nct_id": "NCT00470990",
      "title": "Effect of Varying Testosterone Levels on Insulin Sensitivity in Normal and IHH Men",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hypogonadism"
      ],
      "interventions": [
        {
          "name": "GnRH antagonist (Acyline)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "MALE",
        "summary": "18 Years to 75 Years · Male only"
      },
      "enrollment_count": 40,
      "start_date": "2002-10",
      "completion_date": "2008-06",
      "has_results": false,
      "last_update_posted_date": "2011-04-20",
      "last_synced_at": "2026-09-03T04:50:08.233Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00470990"
    },
    {
      "nct_id": "NCT00839319",
      "title": "HOP-3 Manipulation of the Intratesticular Hormonal Milieu With Exogenous Testosterone",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Healthy Males"
      ],
      "interventions": [
        {
          "name": "Acyline",
          "type": "DRUG"
        },
        {
          "name": "placebo hCG (no active ingredient)",
          "type": "OTHER"
        },
        {
          "name": "hCG (human chorionic gonadotropin)",
          "type": "DRUG"
        },
        {
          "name": "Testosterone gel",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of Washington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "MALE",
        "summary": "18 Years to 50 Years · Male only"
      },
      "enrollment_count": 59,
      "start_date": "2009-03",
      "completion_date": "2010-11",
      "has_results": true,
      "last_update_posted_date": "2016-01-11",
      "last_synced_at": "2026-09-03T04:50:08.233Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00839319"
    },
    {
      "nct_id": "NCT00161447",
      "title": "Male Hormonal Contraceptive Development-ACY-5",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Contraception"
      ],
      "interventions": [
        {
          "name": "Acyline",
          "type": "DRUG"
        },
        {
          "name": "Testosterone Gel",
          "type": "DRUG"
        },
        {
          "name": "Depo-Medroxyprogesterone",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Washington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "MALE",
        "summary": "18 Years to 55 Years · Male only"
      },
      "enrollment_count": 43,
      "start_date": "2004-05",
      "completion_date": "2006-04",
      "has_results": false,
      "last_update_posted_date": "2008-09-19",
      "last_synced_at": "2026-09-03T04:50:08.233Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00161447"
    },
    {
      "nct_id": "NCT02758431",
      "title": "Cardiovascular Outcomes of Low Testosterone",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hypogonadism"
      ],
      "interventions": [
        {
          "name": "Acyline",
          "type": "DRUG"
        },
        {
          "name": "Placebo Gel",
          "type": "DRUG"
        },
        {
          "name": "Placebo Tablet",
          "type": "DRUG"
        },
        {
          "name": "Testosterone Gel",
          "type": "DRUG"
        },
        {
          "name": "Arimidex",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "MALE",
        "summary": "18 Years to 75 Years · Male only"
      },
      "enrollment_count": 232,
      "start_date": "2016-07-01",
      "completion_date": "2023-01-04",
      "has_results": false,
      "last_update_posted_date": "2024-10-10",
      "last_synced_at": "2026-09-03T04:50:08.233Z",
      "location_count": 1,
      "location_summary": "Denver, Colorado",
      "locations": [
        {
          "city": "Denver",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02758431"
    },
    {
      "nct_id": "NCT00842751",
      "title": "Oral T7 Oral Testosterone in Man",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Healthy Males",
        "Male Contraceptive"
      ],
      "interventions": [
        {
          "name": "First Intervention (7 days)",
          "type": "DRUG"
        },
        {
          "name": "First Washout (7 days)",
          "type": "OTHER"
        },
        {
          "name": "Second Intervention (7 days)",
          "type": "DRUG"
        },
        {
          "name": "Third Intervention (7 days)",
          "type": "DRUG"
        },
        {
          "name": "Second wash-out period",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of Washington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "MALE",
        "summary": "18 Years to 50 Years · Male only"
      },
      "enrollment_count": 11,
      "start_date": "2009-07",
      "completion_date": "2009-12",
      "has_results": true,
      "last_update_posted_date": "2014-01-13",
      "last_synced_at": "2026-09-03T04:50:08.233Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00842751"
    },
    {
      "nct_id": "NCT00603187",
      "title": "ACY-7 Oral Administration of Acyline",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "Acyline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Washington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "MALE",
        "summary": "18 Years to 50 Years · Male only"
      },
      "enrollment_count": 4,
      "start_date": "2008-01",
      "completion_date": "2008-02",
      "has_results": true,
      "last_update_posted_date": "2011-06-09",
      "last_synced_at": "2026-09-03T04:50:08.233Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00603187"
    },
    {
      "nct_id": "NCT01686828",
      "title": "T-IR- Study to Understand the Effects of Testosterone and Estrogen on the Body's Response to the Hormone Insulin",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Insulin Resistance",
        "Type 2 Diabetes Mellitus",
        "Obesity",
        "Androgen Deficiency",
        "Metabolic Disease"
      ],
      "interventions": [
        {
          "name": "Acyline",
          "type": "DRUG"
        },
        {
          "name": "Testosterone 1.62% gel",
          "type": "DRUG"
        },
        {
          "name": "Letrozole",
          "type": "DRUG"
        },
        {
          "name": "Placebo gel (for Testosterone 1.62% gel)",
          "type": "DRUG"
        },
        {
          "name": "Placebo pill (for Letrozole)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Washington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "55 Years",
        "sex": "MALE",
        "summary": "25 Years to 55 Years · Male only"
      },
      "enrollment_count": 53,
      "start_date": "2013-06",
      "completion_date": "2017-12",
      "has_results": true,
      "last_update_posted_date": "2018-05-08",
      "last_synced_at": "2026-09-03T04:50:08.233Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01686828"
    },
    {
      "nct_id": "NCT00156650",
      "title": "Manipulation of the Intratesticular Hormonal Milieu With Exogenous Testosterone (HOP 5) Testicular Aspiration Addendum",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Contraception"
      ],
      "interventions": [
        {
          "name": "Acyline",
          "type": "DRUG"
        },
        {
          "name": "Testosterone Gel",
          "type": "DRUG"
        },
        {
          "name": "Depo-Medroxyprogesterone",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Washington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "MALE",
        "summary": "18 Years to 55 Years · Male only"
      },
      "enrollment_count": 23,
      "start_date": "2004-12",
      "completion_date": "2005-07",
      "has_results": false,
      "last_update_posted_date": "2008-09-19",
      "last_synced_at": "2026-09-03T04:50:08.233Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00156650"
    },
    {
      "nct_id": "NCT01327495",
      "title": "PROS-2 Dose Response Effects of Exogenous Testosterone on the Prostate",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "placebo acyline",
          "type": "OTHER"
        },
        {
          "name": "placebo gel",
          "type": "OTHER"
        },
        {
          "name": "Testosterone 1% gel 1.25 g",
          "type": "DRUG"
        },
        {
          "name": "Testosterone 1% gel 2.5 g",
          "type": "DRUG"
        },
        {
          "name": "Testosterone 1% gel 5.0 g",
          "type": "DRUG"
        },
        {
          "name": "testosterone 1% gel 10 g",
          "type": "DRUG"
        },
        {
          "name": "testosterone 1% gel 15 g",
          "type": "DRUG"
        },
        {
          "name": "Acyline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DRUG"
      ],
      "sponsor": "University of Washington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "55 Years",
        "sex": "MALE",
        "summary": "25 Years to 55 Years · Male only"
      },
      "enrollment_count": 62,
      "start_date": "2011-10",
      "completion_date": "2014-12",
      "has_results": true,
      "last_update_posted_date": "2017-10-05",
      "last_synced_at": "2026-09-03T04:50:08.233Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01327495"
    }
  ]
}