{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Advance+Directives&page=2",
    "query": {
      "intervention": "Advance Directives",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Advance+Directives&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-21T04:22:20.790Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04829188",
      "title": "Comparative Effectiveness of Readmission Reduction Interventions for Individuals with Sepsis or Pneumonia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sepsis",
        "Pneumonia",
        "Lower Resp Tract Infection",
        "Covid19"
      ],
      "interventions": [
        {
          "name": "Structured Telephone Support (STS)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Low-intensity Remote Patient Monitoring (RPM-Low)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "High-intensity Remote Patient Monitoring (RPM-High)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Standard Response Team",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Enhanced Response Team",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 1288,
      "start_date": "2021-03-30",
      "completion_date": "2024-12-15",
      "has_results": false,
      "last_update_posted_date": "2025-01-16",
      "last_synced_at": "2026-09-21T04:22:20.790Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04829188"
    },
    {
      "nct_id": "NCT02722382",
      "title": "Putting Patients at the Center of Kidney Care Transitions (PREPARE NOW)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Kidney Disease"
      ],
      "interventions": [
        {
          "name": "Patient-Centered Kidney Transitions Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1572,
      "start_date": "2017-01-31",
      "completion_date": "2020-10-31",
      "has_results": false,
      "last_update_posted_date": "2024-03-25",
      "last_synced_at": "2026-09-21T04:22:20.790Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02722382"
    },
    {
      "nct_id": "NCT02693665",
      "title": "Building Evidence for Effective Palliative/End of Life Care for Teens With Cancer",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cancer"
      ],
      "interventions": [
        {
          "name": "FAmily CEntered Advance Care Planning for Teens with Cancer",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Maureen Lyon",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "14 Years to 99 Years"
      },
      "enrollment_count": 260,
      "start_date": "2016-07-16",
      "completion_date": "2022-09-29",
      "has_results": true,
      "last_update_posted_date": "2025-05-08",
      "last_synced_at": "2026-09-21T04:22:20.790Z",
      "location_count": 4,
      "location_summary": "Washington D.C., District of Columbia • Minneapolis, Minnesota • Akron, Ohio + 1 more",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Akron",
          "state": "Ohio"
        },
        {
          "city": "Memphis",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02693665"
    },
    {
      "nct_id": "NCT02556619",
      "title": "Randomized Control Trial (RCT) of Early Palliative Care for HCC",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Carcinoma, Hepatocellular"
      ],
      "interventions": [
        {
          "name": "Early Palliative Care/Symptom Control",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 72,
      "start_date": "2019-04-02",
      "completion_date": "2021-09",
      "has_results": false,
      "last_update_posted_date": "2021-04-27",
      "last_synced_at": "2026-09-21T04:22:20.790Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02556619"
    },
    {
      "nct_id": "NCT00105794",
      "title": "Psychiatric Advance Directives for Improved Mental Health Care",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Schizophrenia",
        "Schizoaffective",
        "Bipolar Disorder",
        "Stress Disorders, Post-traumatic",
        "Psychotic Disorders"
      ],
      "interventions": [
        {
          "name": "Psychiatric Advance Directives intervention",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "US Department of Veterans Affairs",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 360,
      "start_date": "2004-03",
      "completion_date": "2007-06",
      "has_results": false,
      "last_update_posted_date": "2015-04-07",
      "last_synced_at": "2026-09-21T04:22:20.790Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00105794"
    },
    {
      "nct_id": "NCT06028152",
      "title": "Using an End-of-life Conversation Game to Engage Patients With Cancer in Advance Care Planning",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Breast Cancer",
        "Lung Cancer",
        "Genito Urinary Cancer"
      ],
      "interventions": [
        {
          "name": "End-of-life conversation game called \"Hello\"",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Milton S. Hershey Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 14,
      "start_date": "2023-10-31",
      "completion_date": "2024-01-31",
      "has_results": false,
      "last_update_posted_date": "2024-02-28",
      "last_synced_at": "2026-09-21T04:22:20.790Z",
      "location_count": 1,
      "location_summary": "Hershey, Pennsylvania",
      "locations": [
        {
          "city": "Hershey",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06028152"
    },
    {
      "nct_id": "NCT01817686",
      "title": "Study of Default Options in Advance Directives",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "COPD",
        "Severe or Very Severe Airflow Obstruction and/or Receiving or Eligible to Receive Long-term Oxygen Therapy",
        "Idiopathic Pulmonary Fibrosis",
        "Other Interstitial Lung Disease Without Curative Therapy",
        "Congestive Heart Failure",
        "NYHA Class IV or NYHA Class III Plus 1 Hospitalization in the Past Year",
        "Malignancy",
        "Any Stage 3B or 4 Solid Tumor"
      ],
      "interventions": [
        {
          "name": "Comfort Default AD forms",
          "type": "OTHER"
        },
        {
          "name": "Life Extension Default AD forms",
          "type": "OTHER"
        },
        {
          "name": "Standard Default AD forms",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Corporal Michael J. Crescenz VA Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 62,
      "start_date": "2013-03",
      "completion_date": "2015-06",
      "has_results": false,
      "last_update_posted_date": "2015-06-30",
      "last_synced_at": "2026-09-21T04:22:20.790Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01817686"
    },
    {
      "nct_id": "NCT04281784",
      "title": "Project to Improve Communication About Serious Illness--Hospital Study: Pragmatic Trial (Trial 1)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dementia",
        "Chronic Disease",
        "Neoplasm Metastasis",
        "Lung Neoplasm",
        "Pulmonary Disease, Chronic Obstructive",
        "Heart Failure，Congestive",
        "Liver Cirrhosis",
        "Kidney Failure, Chronic",
        "Lung Diseases, Interstitial",
        "Peripheral Vascular Disease",
        "Diabetes With End Organ Injury"
      ],
      "interventions": [
        {
          "name": "EHR-based Clinician Jumpstart",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Washington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2512,
      "start_date": "2020-04-23",
      "completion_date": "2022-09-26",
      "has_results": true,
      "last_update_posted_date": "2025-04-04",
      "last_synced_at": "2026-09-21T04:22:20.790Z",
      "location_count": 3,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04281784"
    },
    {
      "nct_id": "NCT02612688",
      "title": "Pragmatic Trial of Video Education in Nursing Homes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Alzheimer Disease",
        "Dementia",
        "Heart Failure",
        "Pulmonary Disease, Chronic Obstructive"
      ],
      "interventions": [
        {
          "name": "ACP Video Program",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Brown University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 197692,
      "start_date": "2016-03-01",
      "completion_date": "2019-05-31",
      "has_results": true,
      "last_update_posted_date": "2020-10-12",
      "last_synced_at": "2026-09-21T04:22:20.790Z",
      "location_count": 2,
      "location_summary": "Norcross, Georgia • Kennett Square, Pennsylvania",
      "locations": [
        {
          "city": "Norcross",
          "state": "Georgia"
        },
        {
          "city": "Kennett Square",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02612688"
    },
    {
      "nct_id": "NCT04543201",
      "title": "Telehealth Visits to Discuss Advanced Directives for Patients Newly Diagnosed With High Grade Glioma",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Glioma"
      ],
      "interventions": [
        {
          "name": "Early START visit using checklist over telephone or zoom",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Rochester",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2021-10-08",
      "completion_date": "2026-07-31",
      "has_results": false,
      "last_update_posted_date": "2025-12-18",
      "last_synced_at": "2026-09-21T04:22:20.790Z",
      "location_count": 1,
      "location_summary": "Rochester, New York",
      "locations": [
        {
          "city": "Rochester",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04543201"
    }
  ]
}