{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Affective+challenge",
    "query": {
      "intervention": "Affective challenge"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 9,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-12T02:31:50.219Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06758414",
      "title": "CBT-CP for Veterans With SMI",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Pain",
        "Schizophrenia",
        "Psychotic Disorders",
        "Bipolar Disorder",
        "Affective Disorders, Psychotic"
      ],
      "interventions": [
        {
          "name": "Cognitive Behavioral Therapy for Chronic Pain (CBT-CP)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Health & Wellness (H&W)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 190,
      "start_date": "2026-02-01",
      "completion_date": "2029-09-30",
      "has_results": false,
      "last_update_posted_date": "2026-02-09",
      "last_synced_at": "2026-09-12T02:31:50.219Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06758414"
    },
    {
      "nct_id": "NCT06956781",
      "title": "Multiphase Optimization Strategy (MOST) for Treating Pediatric Post-traumatic Stress Disorder (PTSD)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "PTSD",
        "Trauma",
        "Pediatric ALL"
      ],
      "interventions": [
        {
          "name": "Emotion Regulation",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Exposure",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Cognitive Processing",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Bi-lateral Stimulation",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Psychological Placebo",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Rochester",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "8 Years to 17 Years"
      },
      "enrollment_count": 200,
      "start_date": "2026-03-15",
      "completion_date": "2028-08",
      "has_results": false,
      "last_update_posted_date": "2026-04-08",
      "last_synced_at": "2026-09-12T02:31:50.219Z",
      "location_count": 1,
      "location_summary": "Rochester, New York",
      "locations": [
        {
          "city": "Rochester",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06956781"
    },
    {
      "nct_id": "NCT04118283",
      "title": "Assessment and Treatment for Chronic Pain in Veterans With Serious Mental Illness",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Pain",
        "Schizophrenia",
        "Psychotic Disorders",
        "Bipolar Disorder",
        "Affective Disorders, Psychotic"
      ],
      "interventions": [
        {
          "name": "Cognitive Behavioral Therapy for Chronic Pain",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Health and Wellness",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 47,
      "start_date": "2021-03-18",
      "completion_date": "2025-08-29",
      "has_results": false,
      "last_update_posted_date": "2025-09-23",
      "last_synced_at": "2026-09-12T02:31:50.219Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04118283"
    },
    {
      "nct_id": "NCT05629637",
      "title": "Feasibility and Acceptability of Mindfulness-based Resilience Training for Rural Law Enforcement Officers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Problem Drinking",
        "Aggression",
        "Stress, Psychological"
      ],
      "interventions": [
        {
          "name": "Mindfulness-Based Resilience Training (MBRT)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Pacific University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 20,
      "start_date": "2023-02-01",
      "completion_date": "2024-08-31",
      "has_results": false,
      "last_update_posted_date": "2024-11-12",
      "last_synced_at": "2026-09-12T02:31:50.219Z",
      "location_count": 1,
      "location_summary": "Forest Grove, Oregon",
      "locations": [
        {
          "city": "Forest Grove",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05629637"
    },
    {
      "nct_id": "NCT03705715",
      "title": "Identifying Correlates of Brain Microglial Activation in Neuropsychiatric Syndromes: a Dimensional Approach",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Neuropsychiatric Syndromes"
      ],
      "interventions": [
        {
          "name": "PET with radiotracer [11C]PBR-28 ( or [11C]ER176)",
          "type": "DRUG"
        },
        {
          "name": "Affective challenge",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 200,
      "start_date": "2017-05-01",
      "completion_date": "2028-08",
      "has_results": false,
      "last_update_posted_date": "2025-03-19",
      "last_synced_at": "2026-09-12T02:31:50.219Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03705715"
    },
    {
      "nct_id": "NCT06213883",
      "title": "Response to Acute Exercise in Eating Disorders",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Eating Disorders"
      ],
      "interventions": [
        {
          "name": "Biobehavioral Response to in-lab exposure to physical activity",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": "25 Years",
        "sex": "FEMALE",
        "summary": "16 Years to 25 Years · Female only"
      },
      "enrollment_count": 74,
      "start_date": "2023-11-02",
      "completion_date": "2025-07-31",
      "has_results": true,
      "last_update_posted_date": "2026-08-25",
      "last_synced_at": "2026-09-12T02:31:50.219Z",
      "location_count": 2,
      "location_summary": "San Francisco, California • Madison, Wisconsin",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06213883"
    },
    {
      "nct_id": "NCT02558075",
      "title": "Mood Lifters: A Self Help Program",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Depression",
        "Anxiety",
        "Bipolar Disorder"
      ],
      "interventions": [
        {
          "name": "MoodLifters Sessions",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 200,
      "start_date": "2018-02-01",
      "completion_date": "2022-12-01",
      "has_results": false,
      "last_update_posted_date": "2022-12-27",
      "last_synced_at": "2026-09-12T02:31:50.219Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02558075"
    },
    {
      "nct_id": "NCT03303456",
      "title": "Using Mobile Technology to Enhance Early Psychosis Treatment Delivery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Psychosis",
        "Clinical High Risk for Psychosis"
      ],
      "interventions": [
        {
          "name": "Mobile health application - Ginger.io",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "30 Years",
        "sex": "ALL",
        "summary": "13 Years to 30 Years"
      },
      "enrollment_count": 79,
      "start_date": "2014-12-14",
      "completion_date": "2015-11-01",
      "has_results": false,
      "last_update_posted_date": "2017-10-06",
      "last_synced_at": "2026-09-12T02:31:50.219Z",
      "location_count": 1,
      "location_summary": "Sacramento, California",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03303456"
    },
    {
      "nct_id": "NCT05769634",
      "title": "Electrophysiologic Studies of Cognition in Epilepsy Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Drug-resistant Epilepsy"
      ],
      "interventions": [
        {
          "name": "Stereoelectroencephalography",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Icahn School of Medicine at Mount Sinai",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2022-08-10",
      "completion_date": "2024-05-28",
      "has_results": true,
      "last_update_posted_date": "2025-06-26",
      "last_synced_at": "2026-09-12T02:31:50.219Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05769634"
    }
  ]
}