{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Air+Optix+Night+%26+Day+Aqua",
    "query": {
      "intervention": "Air Optix Night & Day Aqua"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 8,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-10-07T02:44:05.006Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05790928",
      "title": "Air Optix Night and Day Aqua (AONDA) Retrospective Study 1",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Refractive Ametropia",
        "Hyperopia",
        "Myopia"
      ],
      "interventions": [
        {
          "name": "Lotrafilcon A spherical contact lenses",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 108,
      "start_date": "2023-03-25",
      "completion_date": "2023-03-31",
      "has_results": false,
      "last_update_posted_date": "2023-05-25",
      "last_synced_at": "2026-10-07T02:44:05.006Z",
      "location_count": 4,
      "location_summary": "Tallahassee, Florida • Franklin Park, Illinois • Eden Prairie, Minnesota + 1 more",
      "locations": [
        {
          "city": "Tallahassee",
          "state": "Florida"
        },
        {
          "city": "Franklin Park",
          "state": "Illinois"
        },
        {
          "city": "Eden Prairie",
          "state": "Minnesota"
        },
        {
          "city": "Memphis",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05790928"
    },
    {
      "nct_id": "NCT05992675",
      "title": "Air Optix® Night and Day® Aqua Continuous Wear",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Refractive Errors"
      ],
      "interventions": [
        {
          "name": "Lotrafilcon A contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Balafilcon A contact lenses",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1256,
      "start_date": "2023-10-05",
      "completion_date": "2024-08-22",
      "has_results": false,
      "last_update_posted_date": "2024-09-19",
      "last_synced_at": "2026-10-07T02:44:05.006Z",
      "location_count": 8,
      "location_summary": "San Diego, California • Jacksonville, Florida • Miami, Florida + 5 more",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Medina",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05992675"
    },
    {
      "nct_id": "NCT03118934",
      "title": "Assessing Fitting Guides in Alcon Multifocal Contact Lenses",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Presbyopia",
        "Refractive Errors"
      ],
      "interventions": [
        {
          "name": "Lotrafilcon B multifocal contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Nelfilcon A multifocal contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Delefilcon A multifocal contact lenses",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "40 Years to 65 Years"
      },
      "enrollment_count": 188,
      "start_date": "2017-05-17",
      "completion_date": "2017-07-28",
      "has_results": true,
      "last_update_posted_date": "2018-09-26",
      "last_synced_at": "2026-10-07T02:44:05.006Z",
      "location_count": 14,
      "location_summary": "Phoenix, Arizona • San Diego, California • Pensacola, Florida + 10 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Pensacola",
          "state": "Florida"
        },
        {
          "city": "Tallahassee",
          "state": "Florida"
        },
        {
          "city": "Pittsburg",
          "state": "Kansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03118934"
    },
    {
      "nct_id": "NCT05976750",
      "title": "Air Optix® Night and Day® Aqua Daily Wear",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Refractive Errors",
        "Myopia",
        "Hyperopia"
      ],
      "interventions": [
        {
          "name": "Lotrafilcon A contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Balafilcon A contact lenses",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 102,
      "start_date": "2023-10-03",
      "completion_date": "2024-07-30",
      "has_results": false,
      "last_update_posted_date": "2024-08-09",
      "last_synced_at": "2026-10-07T02:44:05.006Z",
      "location_count": 1,
      "location_summary": "Fort Worth, Texas",
      "locations": [
        {
          "city": "Fort Worth",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05976750"
    },
    {
      "nct_id": "NCT05956535",
      "title": "Air Optix® Night and Day® Aqua Therapeutic Wear",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Bullous Keratopathy",
        "Corneal Erosion",
        "Entropion",
        "Corneal Edema",
        "Corneal Dystrophy"
      ],
      "interventions": [
        {
          "name": "Lotrafilcon A contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Balafilcon A contact lenses",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 168,
      "start_date": "2023-09-26",
      "completion_date": "2024-10-25",
      "has_results": false,
      "last_update_posted_date": "2024-11-13",
      "last_synced_at": "2026-10-07T02:44:05.006Z",
      "location_count": 3,
      "location_summary": "Delray Beach, Florida • St Louis, Missouri • Fort Worth, Texas",
      "locations": [
        {
          "city": "Delray Beach",
          "state": "Florida"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        },
        {
          "city": "Fort Worth",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05956535"
    },
    {
      "nct_id": "NCT00937105",
      "title": "Daily Wear Corneal Infiltrative Event Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Myopia",
        "Hyperopia",
        "Corneal Infiltrative Events"
      ],
      "interventions": [
        {
          "name": "lotrafilcon A contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Renu Multiplus",
          "type": "DEVICE"
        },
        {
          "name": "Clear Care",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University Hospitals Cleveland Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "15 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "15 Years and older"
      },
      "enrollment_count": 218,
      "start_date": "2009-11",
      "completion_date": "2012-02",
      "has_results": true,
      "last_update_posted_date": "2014-03-10",
      "last_synced_at": "2026-10-07T02:44:05.006Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00937105"
    },
    {
      "nct_id": "NCT05891106",
      "title": "AONDA Therapeutic Indication Study I",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Bullous Keratopathy",
        "Corneal Erosion",
        "Entropion",
        "Corneal Edema",
        "Corneal Dystrophy",
        "Corneal Ulcer",
        "Foreign Body in Cornea",
        "Bell Palsy",
        "Keratoconjunctivitis",
        "Filamentary Keratitis",
        "Sicca Syndrome; Keratoconjunctivitis (Etiology)"
      ],
      "interventions": [
        {
          "name": "Lotrafilcon A contact lenses",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 55,
      "start_date": "2023-06-28",
      "completion_date": "2023-07-10",
      "has_results": false,
      "last_update_posted_date": "2023-07-20",
      "last_synced_at": "2026-10-07T02:44:05.006Z",
      "location_count": 3,
      "location_summary": "Orlando, Florida • Franklin Park, Illinois • Memphis, Tennessee",
      "locations": [
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Franklin Park",
          "state": "Illinois"
        },
        {
          "city": "Memphis",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05891106"
    },
    {
      "nct_id": "NCT03209505",
      "title": "The Impact of Contact Lens Coefficient of Friction (CoF) on the Development of Lid Wiper Epitheliopathy (LWE)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Lid Wiper Epitheliopathy"
      ],
      "interventions": [
        {
          "name": "Acuvue Oasys",
          "type": "DEVICE"
        },
        {
          "name": "Air Optix Night & Day Aqua",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "46 Years",
        "sex": "ALL",
        "summary": "18 Years to 46 Years"
      },
      "enrollment_count": 20,
      "start_date": "2017-06-26",
      "completion_date": "2018-04-13",
      "has_results": true,
      "last_update_posted_date": "2021-08-31",
      "last_synced_at": "2026-10-07T02:44:05.006Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03209505"
    }
  ]
}