{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Alcohol+%2B+Caffeine-placebo", "query": { "intervention": "Alcohol + Caffeine-placebo" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 16, "total_pages": 2, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Alcohol+%2B+Caffeine-placebo&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-26T02:59:54.805Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT04972123", "title": "The Effect of CPC on Aborting Tilt Induced Syncope in Patients With a History of Vasovagal Syncope or Near Syncope", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Syncope, Vasovagal" ], "interventions": [ { "name": "CPC - Capsaicin, Phenylephrine, Caffeine", "type": "DRUG" }, { "name": "Tilt Table Test", "type": "DIAGNOSTIC_TEST" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG", "DIAGNOSTIC_TEST" ], "sponsor": "University of Wisconsin, Madison", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "50 Years", "sex": "ALL", "summary": "18 Years to 50 Years" }, "enrollment_count": 143, "start_date": "2021-07-20", "completion_date": "2023-08-31", "has_results": true, "last_update_posted_date": "2024-07-17", "last_synced_at": "2026-09-26T02:59:54.805Z", "location_count": 1, "location_summary": "Madison, Wisconsin", "locations": [ { "city": "Madison", "state": "Wisconsin" } ], "official_url": "https://clinicaltrials.gov/study/NCT04972123" }, { "nct_id": "NCT00223691", "title": "Treatment of Orthostatic Hypotension in Autonomic Failure", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Autonomic Failure", "Orthostatic Hypotension" ], "interventions": [ { "name": "Atomoxetine", "type": "DRUG" }, { "name": "Acarbose", "type": "DRUG" }, { "name": "Pyridostigmine Bromide", "type": "DRUG" }, { "name": "Yohimbine", "type": "DRUG" }, { "name": "Midodrine HCl", "type": "DRUG" }, { "name": "placebo", "type": "DRUG" }, { "name": "Modafinil", "type": "DRUG" }, { "name": "Octreotide", "type": "DRUG" }, { "name": "water intake", "type": "OTHER" }, { "name": "Diphenhydramine Hydrochloride", "type": "DRUG" }, { "name": "Ranitidine HCL", "type": "DRUG" }, { "name": "Tranylcypromine", "type": "DRUG" }, { "name": "Ergotamine/ Caffeine", "type": "DRUG" }, { "name": "Celecoxib", "type": "DRUG" }, { "name": "Pseudoephedrine", "type": "DRUG" }, { "name": "Methylphenidate", "type": "DRUG" }, { "name": "Indomethacin", "type": "DRUG" }, { "name": "Ibuprofen", "type": "DRUG" }, { "name": "Oxymetazoline 0.05% nasal solution", "type": "DRUG" }, { "name": "Bovril", "type": "DIETARY_SUPPLEMENT" }, { "name": "Acetazolamide", "type": "DRUG" }, { "name": "Rivastigmine tartrate", "type": "DRUG" }, { "name": "Carbidopa/levodopa", "type": "DRUG" }, { "name": "Inflatable abdominal binder", "type": "DEVICE" }, { "name": "inflatable abdominal binder (sham)", "type": "DEVICE" } ], "intervention_types": [ "DRUG", "OTHER", "DIETARY_SUPPLEMENT", "DEVICE" ], "sponsor": "Vanderbilt University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "18 Years to 85 Years" }, "enrollment_count": 389, "start_date": "2002-03", "completion_date": "2017-01", "has_results": false, "last_update_posted_date": "2017-01-18", "last_synced_at": "2026-09-26T02:59:54.805Z", "location_count": 1, "location_summary": "Nashville, Tennessee", "locations": [ { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT00223691" }, { "nct_id": "NCT00515294", "title": "Acute and Residual Effects of Caffeinated Beer", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Neurobehavioral Manifestations", "Drug Related Sleep Disturbance", "Alcohol Intoxication" ], "interventions": [ { "name": "Caffeinated Alcoholic Beer", "type": "DRUG" }, { "name": "Non-Caffeinated Alcoholic Beer", "type": "OTHER" }, { "name": "Caffeinated Non-Alcoholic Beer", "type": "DRUG" }, { "name": "Non-Caffeinated, Non-Alcoholic Beer", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Boston University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "21 Years", "maximum_age": "30 Years", "sex": "ALL", "summary": "21 Years to 30 Years" }, "enrollment_count": 154, "start_date": "2006-10", "completion_date": "2009-10", "has_results": true, "last_update_posted_date": "2017-06-28", "last_synced_at": "2026-09-26T02:59:54.805Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT00515294" }, { "nct_id": "NCT01048866", "title": "A Study of Flurbiprofen 8.75 mg Lozenge in Patients With Pharyngitis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Pharyngitis" ], "interventions": [ { "name": "placebo", "type": "DRUG" }, { "name": "flurbiprofen", "type": "DRUG" }, { "name": "acetaminophen 650mg", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Reckitt Benckiser LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 198, "start_date": "2009-11", "completion_date": "2011-03", "has_results": true, "last_update_posted_date": "2017-09-21", "last_synced_at": "2026-09-26T02:59:54.805Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT01048866" }, { "nct_id": "NCT00393874", "title": "Efficacy of Sleep Interventions for Posttraumatic Stress Disorder (PTSD)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Anxiety Disorders", "Mood Disorders", "Insomnia", "Nightmares" ], "interventions": [ { "name": "Behavioral Sleep Intervention", "type": "BEHAVIORAL" }, { "name": "Prazosin", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "BEHAVIORAL", "DRUG" ], "sponsor": "University of Pittsburgh", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "18 Years to 55 Years" }, "enrollment_count": 50, "start_date": "2006-10", "completion_date": "2011-06", "has_results": true, "last_update_posted_date": "2016-10-24", "last_synced_at": "2026-09-26T02:59:54.805Z", "location_count": 1, "location_summary": "Pittsburgh, Pennsylvania", "locations": [ { "city": "Pittsburgh", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT00393874" }, { "nct_id": "NCT02530996", "title": "Systemic Sclerosis (SSc) Vasculopathy: Improved Clinical Monitoring and Treatment", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Rheumatologic Disease" ], "interventions": [ { "name": "BH4", "type": "DRUG" }, { "name": "Vasculopathy assessment", "type": "DIAGNOSTIC_TEST" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG", "DIAGNOSTIC_TEST" ], "sponsor": "VA Office of Research and Development", "sponsor_class": "FED", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "95 Years", "sex": "ALL", "summary": "18 Years to 95 Years" }, "enrollment_count": 12, "start_date": "2016-01-01", "completion_date": "2019-12-31", "has_results": true, "last_update_posted_date": "2021-04-05", "last_synced_at": "2026-09-26T02:59:54.805Z", "location_count": 1, "location_summary": "Salt Lake City, Utah", "locations": [ { "city": "Salt Lake City", "state": "Utah" } ], "official_url": "https://clinicaltrials.gov/study/NCT02530996" }, { "nct_id": "NCT00961792", "title": "Chicago Social Drinking Project", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Alcoholism" ], "interventions": [ { "name": "Ethanol", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Diphenhydramine", "type": "DRUG" }, { "name": "Caffeine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Chicago", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "21 Years to 65 Years" }, "enrollment_count": 800, "start_date": "2004-03", "completion_date": "2027-10", "has_results": false, "last_update_posted_date": "2026-04-09", "last_synced_at": "2026-09-26T02:59:54.805Z", "location_count": 1, "location_summary": "Chicago, Illinois", "locations": [ { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT00961792" }, { "nct_id": "NCT01596907", "title": "Treatment of Low Metabolic Rate Following Bariatric Surgery", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Morbid Obesity" ], "interventions": [ { "name": "Ephedrine sulfate with caffeine", "type": "DRUG" }, { "name": "cellulose", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Oregon Weight Loss Surgery, LLC", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 218, "start_date": "2012-05", "completion_date": "2015-07", "has_results": false, "last_update_posted_date": "2015-09-24", "last_synced_at": "2026-09-26T02:59:54.805Z", "location_count": 2, "location_summary": "Beaverton, Oregon • Portland, Oregon", "locations": [ { "city": "Beaverton", "state": "Oregon" }, { "city": "Portland", "state": "Oregon" } ], "official_url": "https://clinicaltrials.gov/study/NCT01596907" }, { "nct_id": "NCT01710722", "title": "The Effect of Leptin A-200, Caffeine/Ephedrine and Their Combination Upon Weight Loss and Body Composition in Man", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Obesity" ], "interventions": [ { "name": "caffeine and ephedrine", "type": "DRUG" }, { "name": "Leptin A", "type": "DRUG" }, { "name": "caffeine, ephedrine, and leptin A", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pennington Biomedical Research Center", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "60 Years", "sex": "ALL", "summary": "18 Years to 60 Years" }, "enrollment_count": 45, "start_date": "2001-02", "completion_date": "2002-02", "has_results": false, "last_update_posted_date": "2015-12-18", "last_synced_at": "2026-09-26T02:59:54.805Z", "location_count": 1, "location_summary": "Baton Rouge, Louisiana", "locations": [ { "city": "Baton Rouge", "state": "Louisiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT01710722" }, { "nct_id": "NCT01950520", "title": "Study of Human Non-Shivering Thermogenesis and Basal Metabolic Rate", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Healthy Volunteers" ], "interventions": [ { "name": "Propranolol", "type": "DRUG" }, { "name": "Pindolol", "type": "DRUG" }, { "name": "Dantrolene", "type": "DRUG" }, { "name": "Magnesium Sulfate", "type": "DRUG" }, { "name": "Caffeine", "type": "DRUG" }, { "name": "Qsymia", "type": "DRUG" }, { "name": "Topiramate", "type": "DRUG" }, { "name": "Phentermine", "type": "BEHAVIORAL" }, { "name": "Naltrexone", "type": "DRUG" }, { "name": "Mirabegron 50mg", "type": "DRUG" }, { "name": "Mirabegron 200mg", "type": "DRUG" }, { "name": "Placebo Cohort 1", "type": "DRUG" }, { "name": "Placebo Cohort 2", "type": "DRUG" }, { "name": "Placebo for Mirabegron", "type": "DRUG" } ], "intervention_types": [ "DRUG", "BEHAVIORAL" ], "sponsor": "National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)", "sponsor_class": "NIH", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "35 Years", "sex": "MALE", "summary": "18 Years to 35 Years · Male only" }, "enrollment_count": 47, "start_date": "2014-02-07", "completion_date": "2024-06-11", "has_results": true, "last_update_posted_date": "2024-10-16", "last_synced_at": "2026-09-26T02:59:54.805Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT01950520" } ] }