{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Amoxicillin+250+MG",
    "query": {
      "intervention": "Amoxicillin 250 MG"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 16,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Amoxicillin+250+MG&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-22T15:42:34.020Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01098448",
      "title": "Control of Periodontal Infections",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Periodontitis"
      ],
      "interventions": [
        {
          "name": "scaling and root planing",
          "type": "OTHER"
        },
        {
          "name": "local tetracycline",
          "type": "DRUG"
        },
        {
          "name": "systemic metronidazole and amoxicillin",
          "type": "DRUG"
        },
        {
          "name": "surgery",
          "type": "OTHER"
        },
        {
          "name": "local antibiotics and systemic metronidazole and amoxicillin",
          "type": "DRUG"
        },
        {
          "name": "local tetracycline and periodontal surgery",
          "type": "OTHER"
        },
        {
          "name": "periodontal surgery and systemic metronidazole and amoxicillin",
          "type": "OTHER"
        },
        {
          "name": "surgery, local tetracycline, systemic metronidazole and amoxicillin",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DRUG"
      ],
      "sponsor": "The Forsyth Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "20 Years and older"
      },
      "enrollment_count": 187,
      "start_date": "1999-09",
      "completion_date": "2004-12",
      "has_results": false,
      "last_update_posted_date": "2010-04-02",
      "last_synced_at": "2026-09-22T15:42:34.020Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01098448"
    },
    {
      "nct_id": "NCT06396078",
      "title": "Improvement of PPROM Management With Prophylactic Antimicrobial Therapy (iPROMPT)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Preterm Premature Rupture of Membrane",
        "Pregnancy, High Risk",
        "Preterm Birth"
      ],
      "interventions": [
        {
          "name": "Ceftriaxone 1000 MG",
          "type": "DRUG"
        },
        {
          "name": "Clarithromycin 500mg",
          "type": "DRUG"
        },
        {
          "name": "Metronidazole 500 mg",
          "type": "DRUG"
        },
        {
          "name": "Ampicillin 2 GM Injection",
          "type": "DRUG"
        },
        {
          "name": "Amoxicillin 250 MG",
          "type": "DRUG"
        },
        {
          "name": "Azithromycin",
          "type": "DRUG"
        },
        {
          "name": "Erythromycin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Ohio State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 56,
      "start_date": "2024-07-18",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2026-01-27",
      "last_synced_at": "2026-09-22T15:42:34.020Z",
      "location_count": 2,
      "location_summary": "Columbus, Ohio • Galveston, Texas",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        },
        {
          "city": "Galveston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06396078"
    },
    {
      "nct_id": "NCT06303128",
      "title": "Penicillin Allergy Delabeling After a One-Dose Versus Two-Dose Graded Direct Oral Challenge",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Penicillin Allergy"
      ],
      "interventions": [
        {
          "name": "Amoxicillin 250 MG",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "Amoxicillin 62.5mg",
          "type": "DRUG"
        },
        {
          "name": "Amoxicillin 187.5mg",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "James Tarbox, MD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "18 Years to 89 Years"
      },
      "enrollment_count": 380,
      "start_date": "2024-02-03",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2025-05-01",
      "last_synced_at": "2026-09-22T15:42:34.020Z",
      "location_count": 1,
      "location_summary": "Lubbock, Texas",
      "locations": [
        {
          "city": "Lubbock",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06303128"
    },
    {
      "nct_id": "NCT07669207",
      "title": "Extended Azithromycin Treatment in Prelabor Rupture of Membranes",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Preterm Prelabor Rupture of Membranes",
        "PPROM"
      ],
      "interventions": [
        {
          "name": "Azithromycin (Azithro)",
          "type": "DRUG"
        },
        {
          "name": "Standard Azithromycin Dosing",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Alexa Henderson",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "Female only"
      },
      "enrollment_count": 30,
      "start_date": "2026-08-19",
      "completion_date": "2028-07",
      "has_results": false,
      "last_update_posted_date": "2026-09-04",
      "last_synced_at": "2026-09-22T15:42:34.020Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07669207"
    },
    {
      "nct_id": "NCT00095368",
      "title": "APC-111 Once a Day (QD) for 7 Days vs. Penicillin Taken Four Times a Day (QID) for 10 Days in Patients With Strep Throat",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Pharyngitis",
        "Tonsillitis"
      ],
      "interventions": [
        {
          "name": "Amoxicillin Pulsatile Release Multiparticulate Tablet (drug)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Advancis Pharmaceutical Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "12 Years and older"
      },
      "enrollment_count": 500,
      "start_date": "2004-10",
      "completion_date": "2005-05",
      "has_results": false,
      "last_update_posted_date": "2006-12-08",
      "last_synced_at": "2026-09-22T15:42:34.020Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00095368"
    },
    {
      "nct_id": "NCT01568944",
      "title": "Role of Infected Blood Dendritic Cells in Heart Disease Risk",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Periodontitis"
      ],
      "interventions": [
        {
          "name": "Oral Antibiotic and Oral Rinse",
          "type": "DRUG"
        },
        {
          "name": "Standard Treatment",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "Augusta University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 18,
      "start_date": "2012-03",
      "completion_date": "2014-09",
      "has_results": true,
      "last_update_posted_date": "2020-05-12",
      "last_synced_at": "2026-09-22T15:42:34.020Z",
      "location_count": 1,
      "location_summary": "Augusta, Georgia",
      "locations": [
        {
          "city": "Augusta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01568944"
    },
    {
      "nct_id": "NCT04620746",
      "title": "Penicillin Allergy Testing in STD Clinics",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Penicillin Allergy"
      ],
      "interventions": [
        {
          "name": "Penicillin Major Determinant (PrePen) Skin Testing",
          "type": "DRUG"
        },
        {
          "name": "Direct Oral challenge",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 284,
      "start_date": "2021-06-01",
      "completion_date": "2022-12-31",
      "has_results": true,
      "last_update_posted_date": "2023-09-21",
      "last_synced_at": "2026-09-22T15:42:34.020Z",
      "location_count": 2,
      "location_summary": "New Orleans, Louisiana • Seattle, Washington",
      "locations": [
        {
          "city": "New Orleans",
          "state": "Louisiana"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04620746"
    },
    {
      "nct_id": "NCT03211156",
      "title": "Treatment of Gardnerella Vaginalis Vaginal Colonization With Amoxicillin",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Vaginitis Gardnerella"
      ],
      "interventions": [
        {
          "name": "Amoxicillin",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 97,
      "start_date": "2017-09-11",
      "completion_date": "2019-08-22",
      "has_results": true,
      "last_update_posted_date": "2020-08-28",
      "last_synced_at": "2026-09-22T15:42:34.020Z",
      "location_count": 2,
      "location_summary": "Birmingham, Alabama • Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03211156"
    },
    {
      "nct_id": "NCT01330719",
      "title": "Mechanisms and Treatment Response of Aggressive Periodontitis in Children",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aggressive Periodontitis"
      ],
      "interventions": [
        {
          "name": "Diseased periodontal treatment",
          "type": "PROCEDURE"
        },
        {
          "name": "Conventional periodontal treatment",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "5 Years to 90 Years"
      },
      "enrollment_count": 514,
      "start_date": "2006-12",
      "completion_date": "2022-12-02",
      "has_results": false,
      "last_update_posted_date": "2024-03-12",
      "last_synced_at": "2026-09-22T15:42:34.020Z",
      "location_count": 10,
      "location_summary": "Brooker, Florida • Fort Lauderdale, Florida • Gainesville, Florida + 6 more",
      "locations": [
        {
          "city": "Brooker",
          "state": "Florida"
        },
        {
          "city": "Fort Lauderdale",
          "state": "Florida"
        },
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Hialeah",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01330719"
    },
    {
      "nct_id": "NCT01980095",
      "title": "ERADICATE Hp - Treating Helicobacter Pylori With RHB-105",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Dyspepsia",
        "Helicobacter Pylori Infection"
      ],
      "interventions": [
        {
          "name": "RHB-105",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "RedHill Biopharma Limited",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 119,
      "start_date": "2013-11",
      "completion_date": "2015-08",
      "has_results": true,
      "last_update_posted_date": "2019-09-24",
      "last_synced_at": "2026-09-22T15:42:34.020Z",
      "location_count": 12,
      "location_summary": "Anaheim, California • Chino, California • Jupiter, Florida + 8 more",
      "locations": [
        {
          "city": "Anaheim",
          "state": "California"
        },
        {
          "city": "Anaheim",
          "state": "California"
        },
        {
          "city": "Chino",
          "state": "California"
        },
        {
          "city": "Jupiter",
          "state": "Florida"
        },
        {
          "city": "Columbus",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01980095"
    }
  ]
}