{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Amoxicillin+trihydrate",
    "query": {
      "intervention": "Amoxicillin trihydrate"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 149,
    "total_pages": 15,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Amoxicillin+trihydrate&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-14T07:43:42.651Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03357614",
      "title": "Sulopenem Followed by Sulopenem-etzadroxil/Probenecid vs Ertapenem Followed by Cipro for Complicated UTI in Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Complicated Urinary Tract Infections"
      ],
      "interventions": [
        {
          "name": "Sulopenem",
          "type": "DRUG"
        },
        {
          "name": "Sulopenem-Etzadroxil/Probenecid",
          "type": "DRUG"
        },
        {
          "name": "Ertapenem",
          "type": "DRUG"
        },
        {
          "name": "Ciprofloxacin",
          "type": "DRUG"
        },
        {
          "name": "Amoxicillin-clavulanate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Iterum Therapeutics, International Limited",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1395,
      "start_date": "2018-09-18",
      "completion_date": "2019-12-14",
      "has_results": true,
      "last_update_posted_date": "2020-12-29",
      "last_synced_at": "2026-09-14T07:43:42.651Z",
      "location_count": 15,
      "location_summary": "Bellflower, California • Chula Vista, California • La Mesa, California + 11 more",
      "locations": [
        {
          "city": "Bellflower",
          "state": "California"
        },
        {
          "city": "Chula Vista",
          "state": "California"
        },
        {
          "city": "La Mesa",
          "state": "California"
        },
        {
          "city": "La Palma",
          "state": "California"
        },
        {
          "city": "Torrance",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03357614"
    },
    {
      "nct_id": "NCT05309928",
      "title": "Phase 1 Study of the Pharmacokinetics of Amoxicillin in Pregnancy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Pregnancy Related"
      ],
      "interventions": [
        {
          "name": "Amoxicillin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "16 Years to 50 Years · Female only"
      },
      "enrollment_count": 13,
      "start_date": "2023-08-29",
      "completion_date": "2025-06-30",
      "has_results": false,
      "last_update_posted_date": "2025-12-17",
      "last_synced_at": "2026-09-14T07:43:42.651Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05309928"
    },
    {
      "nct_id": "NCT01723059",
      "title": "Standard Triple Therapy vs Sequential Therapy in Treatment of H Pylori Infection",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Helicobacter Infection"
      ],
      "interventions": [
        {
          "name": "Standard Triple Therapy",
          "type": "DRUG"
        },
        {
          "name": "Sequential Therapy",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Dallas VA Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 184,
      "start_date": "2012-02",
      "completion_date": "2013-01",
      "has_results": false,
      "last_update_posted_date": "2012-11-07",
      "last_synced_at": "2026-09-14T07:43:42.651Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01723059"
    },
    {
      "nct_id": "NCT04020458",
      "title": "Dental Intervention Plan for Chronic Kidney Disease Patients Awaiting or With Kidney Transplant",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Kidney Disease",
        "Chronic Periodontitis, Generalized, Moderate"
      ],
      "interventions": [
        {
          "name": "dental intervention",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Augusta University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "21 Years to 75 Years"
      },
      "enrollment_count": 11,
      "start_date": "2018-11-09",
      "completion_date": "2022-01-04",
      "has_results": false,
      "last_update_posted_date": "2023-07-21",
      "last_synced_at": "2026-09-14T07:43:42.651Z",
      "location_count": 1,
      "location_summary": "Augusta, Georgia",
      "locations": [
        {
          "city": "Augusta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04020458"
    },
    {
      "nct_id": "NCT03431337",
      "title": "Treatment of Acute Sinusitis With High-Dose vs. Standard-Dose Amoxicillin/Clavulanate",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Sinusitis, Acute"
      ],
      "interventions": [
        {
          "name": "Amoxicillin 875 mg",
          "type": "DRUG"
        },
        {
          "name": "Placebo (lactase)",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Paul Sorum, MD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 157,
      "start_date": "2018-02-26",
      "completion_date": "2020-05-31",
      "has_results": true,
      "last_update_posted_date": "2021-08-12",
      "last_synced_at": "2026-09-14T07:43:42.651Z",
      "location_count": 1,
      "location_summary": "Cohoes, New York",
      "locations": [
        {
          "city": "Cohoes",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03431337"
    },
    {
      "nct_id": "NCT01069900",
      "title": "Moxifloxacin in Pediatric Subjects With Complicated Intra-abdominal Infection",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Intraabdominal Infections"
      ],
      "interventions": [
        {
          "name": "Moxifloxacin (Avelox, BAY12-8039)",
          "type": "DRUG"
        },
        {
          "name": "Ertapenem",
          "type": "DRUG"
        },
        {
          "name": "Amoxicillin/Clavulanate",
          "type": "DRUG"
        },
        {
          "name": "Moxifloxacin placebo",
          "type": "DRUG"
        },
        {
          "name": "Ertapenem placebo",
          "type": "DRUG"
        },
        {
          "name": "Amoxicillin/Clavulanate placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Bayer",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "3 Months",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "3 Months to 17 Years"
      },
      "enrollment_count": 458,
      "start_date": "2010-07-21",
      "completion_date": "2015-01-21",
      "has_results": true,
      "last_update_posted_date": "2018-03-20",
      "last_synced_at": "2026-09-14T07:43:42.651Z",
      "location_count": 2,
      "location_summary": "San Diego, California • Springfield, Massachusetts",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Springfield",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01069900"
    },
    {
      "nct_id": "NCT04963764",
      "title": "Procalcitonin to Reduce Antibiotic Use in Pediatric Pneumonia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Pneumonia",
        "Pediatric Respiratory Diseases",
        "Antibiotic Use",
        "Community-acquired Pneumonia"
      ],
      "interventions": [
        {
          "name": "Amoxicillin",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Ann & Robert H Lurie Children's Hospital of Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Months",
        "maximum_age": "71 Months",
        "sex": "ALL",
        "summary": "12 Months to 71 Months"
      },
      "enrollment_count": 5,
      "start_date": "2021-10-18",
      "completion_date": "2022-05-27",
      "has_results": true,
      "last_update_posted_date": "2024-02-15",
      "last_synced_at": "2026-09-14T07:43:42.651Z",
      "location_count": 3,
      "location_summary": "Chicago, Illinois • Cincinnati, Ohio • Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04963764"
    },
    {
      "nct_id": "NCT05010304",
      "title": "Penicillin De-labeling in the Pediatric Primary Care Setting",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Penicillin Allergy",
        "Penicillin Reaction"
      ],
      "interventions": [
        {
          "name": "Amoxicillin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "2 Years to 18 Years"
      },
      "enrollment_count": 23,
      "start_date": "2021-12-09",
      "completion_date": "2023-11-30",
      "has_results": true,
      "last_update_posted_date": "2024-08-14",
      "last_synced_at": "2026-09-14T07:43:42.651Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05010304"
    },
    {
      "nct_id": "NCT00100126",
      "title": "APC-231 Once a Day (QD) for 7 Days vs. Penicillin Taken Four Times a Day (QID) in Pediatric Patients With Strep Throat",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Pharyngitis"
      ],
      "interventions": [
        {
          "name": "Amoxicillin Pulsatile Release Multiparticluate Sprinkle",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Advancis Pharmaceutical Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Months",
        "maximum_age": "12 Years",
        "sex": "ALL",
        "summary": "6 Months to 12 Years"
      },
      "enrollment_count": 500,
      "start_date": "2004-12",
      "completion_date": "2005-06",
      "has_results": false,
      "last_update_posted_date": "2006-10-25",
      "last_synced_at": "2026-09-14T07:43:42.651Z",
      "location_count": 2,
      "location_summary": "Simpsonville, South Carolina • Salt Lake City, Utah",
      "locations": [
        {
          "city": "Simpsonville",
          "state": "South Carolina"
        },
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00100126"
    },
    {
      "nct_id": "NCT03358576",
      "title": "Sulopenem Versus Ertapenem for Complicated Intra-abdominal Infection (cIAI)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Intra Abdominal Infections"
      ],
      "interventions": [
        {
          "name": "Ertapenem",
          "type": "DRUG"
        },
        {
          "name": "Sulopenem-Etzadroxil/Probenecid",
          "type": "DRUG"
        },
        {
          "name": "Ciprofloxacin",
          "type": "DRUG"
        },
        {
          "name": "Metronidazole",
          "type": "DRUG"
        },
        {
          "name": "Amoxicillin-Clavulanate",
          "type": "DRUG"
        },
        {
          "name": "Sulopenem",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Iterum Therapeutics, International Limited",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 674,
      "start_date": "2018-09-18",
      "completion_date": "2019-10-02",
      "has_results": true,
      "last_update_posted_date": "2020-12-01",
      "last_synced_at": "2026-09-14T07:43:42.651Z",
      "location_count": 12,
      "location_summary": "Chula Vista, California • Torrance, California • Idaho Falls, Idaho + 8 more",
      "locations": [
        {
          "city": "Chula Vista",
          "state": "California"
        },
        {
          "city": "Torrance",
          "state": "California"
        },
        {
          "city": "Idaho Falls",
          "state": "Idaho"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Royal Oak",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03358576"
    }
  ]
}