{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Antegrade+Perfusion",
    "query": {
      "intervention": "Antegrade Perfusion"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 4,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-05T08:27:05.075Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06986967",
      "title": "Retrograde Versus Antegrade Perfusion in Low-Moderate Hypothermia for Aortic Arch Surgery",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Brain Function",
        "Hemiarch Cardiac Procedure"
      ],
      "interventions": [
        {
          "name": "Antegrade Perfusion",
          "type": "PROCEDURE"
        },
        {
          "name": "Retrograde Perfusion",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2025-04-18",
      "completion_date": "2027-03",
      "has_results": false,
      "last_update_posted_date": "2026-09-03",
      "last_synced_at": "2026-09-05T08:27:05.075Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06986967"
    },
    {
      "nct_id": "NCT00606190",
      "title": "Prospective Randomized Study of Brain Protection During Aortic Arch Replacement",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aneurysm of Aortic Arch"
      ],
      "interventions": [
        {
          "name": "Retrograde brain perfusion",
          "type": "PROCEDURE"
        },
        {
          "name": "Antegrade brain perfusion",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "The Cleveland Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "74 Years",
        "sex": "ALL",
        "summary": "21 Years to 74 Years"
      },
      "enrollment_count": 123,
      "start_date": "2003-06",
      "completion_date": "2010-04",
      "has_results": false,
      "last_update_posted_date": "2017-02-17",
      "last_synced_at": "2026-09-05T08:27:05.075Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00606190"
    },
    {
      "nct_id": "NCT02750423",
      "title": "Neurologic Injury Following Aortic Arch Replacement",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aortic Arch Replacement",
        "Hemi Arch Replacement"
      ],
      "interventions": [
        {
          "name": "DHCA+RCP",
          "type": "PROCEDURE"
        },
        {
          "name": "MHCA + SACP",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2016-04",
      "completion_date": "2017-12",
      "has_results": false,
      "last_update_posted_date": "2018-03-30",
      "last_synced_at": "2026-09-05T08:27:05.075Z",
      "location_count": 2,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02750423"
    },
    {
      "nct_id": "NCT02860364",
      "title": "Comparing Hypothermic Temperatures During Hemiarch Surgery",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Thoracic Aortic Disease"
      ],
      "interventions": [
        {
          "name": "Hypothermic circulatory arrest",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Ottawa Heart Institute Research Corporation",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 282,
      "start_date": "2018-02-20",
      "completion_date": "2030-12",
      "has_results": false,
      "last_update_posted_date": "2025-09-24",
      "last_synced_at": "2026-09-05T08:27:05.075Z",
      "location_count": 3,
      "location_summary": "Boston, Massachusetts • Ridgewood, New Jersey • Columbus, Ohio",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Ridgewood",
          "state": "New Jersey"
        },
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02860364"
    }
  ]
}