{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Anterior+cervical+discectomy+and+fusion",
    "query": {
      "intervention": "Anterior cervical discectomy and fusion"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 59,
    "total_pages": 6,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Anterior+cervical+discectomy+and+fusion&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-10-06T13:41:49.627Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03077204",
      "title": "BIO4 Clinical Case Study: Cervical Spine",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Degenerative Disc Disease",
        "Trauma (Including Fractures)",
        "Spondylolisthesis"
      ],
      "interventions": [
        {
          "name": "1 or 2-Level ACDF utilizing BIO4 with Bio AVS Cervical Allograft (with graft window).",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Aviator Anterior Cervical Plating System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "DEVICE"
      ],
      "sponsor": "Seton Healthcare Family",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "19 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2017-04-06",
      "completion_date": "2020-01-30",
      "has_results": true,
      "last_update_posted_date": "2022-01-14",
      "last_synced_at": "2026-10-06T13:41:49.627Z",
      "location_count": 1,
      "location_summary": "Austin, Texas",
      "locations": [
        {
          "city": "Austin",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03077204"
    },
    {
      "nct_id": "NCT05653206",
      "title": "Incomplete Cervical SCI Without Instability",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cervical Spinal Cord Injury"
      ],
      "interventions": [
        {
          "name": "Nonsurgical treatment",
          "type": "PROCEDURE"
        },
        {
          "name": "Surgical treatment",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "AO Foundation, AO Spine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 50,
      "start_date": "2023-12-11",
      "completion_date": "2026-08-18",
      "has_results": false,
      "last_update_posted_date": "2026-10-06",
      "last_synced_at": "2026-10-06T13:41:49.627Z",
      "location_count": 3,
      "location_summary": "San Francisco, California • Baltimore, Maryland • Milwaukee, Wisconsin",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Milwaukee",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05653206"
    },
    {
      "nct_id": "NCT04684901",
      "title": "Effectiveness of AlloWrap® for the Reduction of Inflammation in ACDF Procedures",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cervical Stenosis",
        "Spondylolisthesis",
        "Cervical Radiculopathy",
        "Cervical Disc Disorder"
      ],
      "interventions": [
        {
          "name": "AlloWrap® Amniotic Membrane",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "AlloSource",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2021-01-18",
      "completion_date": "2027-12",
      "has_results": false,
      "last_update_posted_date": "2025-11-21",
      "last_synced_at": "2026-10-06T13:41:49.627Z",
      "location_count": 1,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04684901"
    },
    {
      "nct_id": "NCT05101057",
      "title": "A Retrospective Study to Examine the Effect of CMF Stimulation on Primary ACDF Patients",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Degeneration of Cervical Intervertebral Disc"
      ],
      "interventions": [
        {
          "name": "SpinalogicTM Bone Graft Stimulator",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Encore Medical, L.P.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 400,
      "start_date": "2021-11-15",
      "completion_date": "2022-06-01",
      "has_results": false,
      "last_update_posted_date": "2021-12-07",
      "last_synced_at": "2026-10-06T13:41:49.627Z",
      "location_count": 2,
      "location_summary": "San Diego, California • White Plains, New York",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "White Plains",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05101057"
    },
    {
      "nct_id": "NCT02720172",
      "title": "Early Postoperative Home Exercise Program After Cervical Spine Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Spinal Fusion",
        "Cervical Spine Degenerative Disease"
      ],
      "interventions": [
        {
          "name": "Early Home Exercise Program",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Usual Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2016-03",
      "completion_date": "2018-07",
      "has_results": false,
      "last_update_posted_date": "2019-02-12",
      "last_synced_at": "2026-10-06T13:41:49.627Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02720172"
    },
    {
      "nct_id": "NCT02724761",
      "title": "Prophylactic Racemic Epinephrine in Anterior Cervical Discectomy and Fusion",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dysphagia",
        "Dysphonia",
        "Postoperative Pain"
      ],
      "interventions": [
        {
          "name": "Racemic Epinephrine",
          "type": "DRUG"
        },
        {
          "name": "Placebo (for racemic epinephrine)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Andrew Chung",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 90,
      "start_date": "2016-09",
      "completion_date": "2018-09",
      "has_results": false,
      "last_update_posted_date": "2016-03-31",
      "last_synced_at": "2026-10-06T13:41:49.627Z",
      "location_count": 1,
      "location_summary": "Phoenix, Arizona",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02724761"
    },
    {
      "nct_id": "NCT03786432",
      "title": "Prospective Study of Fusion Rates Using Spira-C Device for Anterior Cervical Discectomy and Fusion Surgery",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cervical Radiculopathy",
        "Cervical Disc Disease"
      ],
      "interventions": [
        {
          "name": "Spira-C Interbody Device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Corewell Health East",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 13,
      "start_date": "2019-01-10",
      "completion_date": "2022-06-30",
      "has_results": true,
      "last_update_posted_date": "2023-07-28",
      "last_synced_at": "2026-10-06T13:41:49.627Z",
      "location_count": 1,
      "location_summary": "Royal Oak, Michigan",
      "locations": [
        {
          "city": "Royal Oak",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03786432"
    },
    {
      "nct_id": "NCT00637312",
      "title": "Advent™ Cervical Disc Versus ACDF for Treatment of One Level Degenerative Disc Disease (IDE Study)",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cervical Degenerative Disc Disease"
      ],
      "interventions": [
        {
          "name": "Cervical Artificial Disc (Advent™ Cervical Disc)",
          "type": "DEVICE"
        },
        {
          "name": "Hallmark™ Anterior Cervical Plate System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Orthofix Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 108,
      "start_date": "2008-03",
      "completion_date": "2013-02",
      "has_results": true,
      "last_update_posted_date": "2014-03-27",
      "last_synced_at": "2026-10-06T13:41:49.627Z",
      "location_count": 13,
      "location_summary": "Sacramento, California • Boulder, Colorado • Tampa, Florida + 10 more",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Boulder",
          "state": "Colorado"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "Shreveport",
          "state": "Louisiana"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00637312"
    },
    {
      "nct_id": "NCT01097486",
      "title": "Safety and Preliminary Efficacy Study of NeoFuse in Subjects Undergoing Multi-Level Anterior Cervical Discectomy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Cervical Degenerative Disc Disease",
        "Degenerative Spondylolisthesis",
        "Spinal Stenosis"
      ],
      "interventions": [
        {
          "name": "NeoFuse",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Allograft",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "PROCEDURE"
      ],
      "sponsor": "Mesoblast, Ltd.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 24,
      "start_date": "2010-06",
      "completion_date": "2014-07",
      "has_results": false,
      "last_update_posted_date": "2019-08-16",
      "last_synced_at": "2026-10-06T13:41:49.627Z",
      "location_count": 8,
      "location_summary": "Sacramento, California • Santa Monica, California • Denver, Colorado + 5 more",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Santa Monica",
          "state": "California"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Loveland",
          "state": "Colorado"
        },
        {
          "city": "Tallahassee",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01097486"
    },
    {
      "nct_id": "NCT00726128",
      "title": "Patient Outcomes Evaluation of the EBI Vuelock™ Anterior Cervical Plate System",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Trauma",
        "Tumor",
        "Pseudarthrosis",
        "Scoliosis",
        "Degenerative Disc Disease"
      ],
      "interventions": [
        {
          "name": "VueLock™ Anterior Cervical Plate",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Zimmer Biomet",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 371,
      "start_date": "1998-08",
      "completion_date": "2009-09",
      "has_results": false,
      "last_update_posted_date": "2020-02-24",
      "last_synced_at": "2026-10-06T13:41:49.627Z",
      "location_count": 4,
      "location_summary": "Palo Alto, California • San Diego, California • Avon, Indiana + 1 more",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Avon",
          "state": "Indiana"
        },
        {
          "city": "Raleigh",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00726128"
    }
  ]
}