{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Anti-reflux+surgery",
    "query": {
      "intervention": "Anti-reflux surgery"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 17,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Anti-reflux+surgery&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-05T06:14:35.628Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02211105",
      "title": "Registry to Compare Two Surgical Treatments for GERD",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "GastroEsophageal Reflux Disease"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "American Gastroenterological Association",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 46,
      "start_date": "2014-07",
      "completion_date": "2017-04",
      "has_results": false,
      "last_update_posted_date": "2018-01-09",
      "last_synced_at": "2026-09-05T06:14:35.628Z",
      "location_count": 10,
      "location_summary": "Huntington Beach, California • Englewood, Colorado • Chicago, Illinois + 7 more",
      "locations": [
        {
          "city": "Huntington Beach",
          "state": "California"
        },
        {
          "city": "Englewood",
          "state": "Colorado"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Evanston",
          "state": "Illinois"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02211105"
    },
    {
      "nct_id": "NCT01260935",
      "title": "Comparison of Laparoscopic Hill and Laparoscopic Nissen Anti-Reflux Procedures",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Gastroesophageal Reflux",
        "Esophageal Reflux",
        "Gastroesophageal Reflux Disease",
        "GERD"
      ],
      "interventions": [
        {
          "name": "Laparoscopic Hill Repair",
          "type": "PROCEDURE"
        },
        {
          "name": "Laparoscopic Nissen Repair",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Swedish Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 121,
      "start_date": "2002-11",
      "completion_date": "2010-11",
      "has_results": false,
      "last_update_posted_date": "2012-01-18",
      "last_synced_at": "2026-09-05T06:14:35.628Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01260935"
    },
    {
      "nct_id": "NCT07659080",
      "title": "Antireflux Surgery Without Preoperative Esophageal Manometry",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "GERD",
        "Hiatal Hernia",
        "Heartburn",
        "Paraesophageal Hernia",
        "Gastroesophageal Reflux"
      ],
      "interventions": [
        {
          "name": "Preoperative workup without high-resolution esophageal manometry",
          "type": "PROCEDURE"
        },
        {
          "name": "Standard preoperative workup with high-resolution esophageal manometry",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "McMaster University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 96,
      "start_date": "2026-10-01",
      "completion_date": "2028-04-30",
      "has_results": false,
      "last_update_posted_date": "2026-08-10",
      "last_synced_at": "2026-09-05T06:14:35.628Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07659080"
    },
    {
      "nct_id": "NCT00624546",
      "title": "Effect of Antireflux Therapy on the Expression of Genes in Patients With GERD",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "GERD",
        "Gastroesophageal Reflux"
      ],
      "interventions": [
        {
          "name": "Prevacid Solutabs",
          "type": "DRUG"
        },
        {
          "name": "Antireflux surgery",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "University of Rochester",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "74 Years",
        "sex": "ALL",
        "summary": "18 Years to 74 Years"
      },
      "enrollment_count": 24,
      "start_date": "2009-01",
      "completion_date": "2014-01",
      "has_results": false,
      "last_update_posted_date": "2015-10-26",
      "last_synced_at": "2026-09-05T06:14:35.628Z",
      "location_count": 1,
      "location_summary": "Rochester, New York",
      "locations": [
        {
          "city": "Rochester",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00624546"
    },
    {
      "nct_id": "NCT00830479",
      "title": "Study of Endoscopic Versus Open Surgery for Urinary Reflux",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Vesicoureteral Reflux"
      ],
      "interventions": [
        {
          "name": "Anti-reflux surgery",
          "type": "PROCEDURE"
        },
        {
          "name": "Endoscopic injection",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "11 Years",
        "sex": "ALL",
        "summary": "Up to 11 Years"
      },
      "enrollment_count": 0,
      "start_date": "2009-01",
      "completion_date": "2011-01",
      "has_results": false,
      "last_update_posted_date": "2011-08-12",
      "last_synced_at": "2026-09-05T06:14:35.628Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00830479"
    },
    {
      "nct_id": "NCT01982968",
      "title": "Treatment of IPF With Laparoscopic Anti-Reflux Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Idiopathic Pulmonary Fibrosis",
        "Gastroesophageal Reflux"
      ],
      "interventions": [
        {
          "name": "Surgery",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 58,
      "start_date": "2013-12",
      "completion_date": "2017-11",
      "has_results": true,
      "last_update_posted_date": "2021-10-25",
      "last_synced_at": "2026-09-05T06:14:35.628Z",
      "location_count": 5,
      "location_summary": "San Francisco, California • Chicago, Illinois • Ann Arbor, Michigan + 2 more",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        },
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01982968"
    },
    {
      "nct_id": "NCT01241149",
      "title": "Prospective Evaluation of Symptom Resolution in Acid Versus Non-acid Reflux Disease Following Anti-reflux Surgery",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Non-acid Reflux Disease"
      ],
      "interventions": [
        {
          "name": "anti-reflux surgery",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "United States Naval Medical Center, Portsmouth",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "17 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "17 Years and older"
      },
      "enrollment_count": 12,
      "start_date": "2010-11",
      "completion_date": "2014-03-26",
      "has_results": false,
      "last_update_posted_date": "2025-08-15",
      "last_synced_at": "2026-09-05T06:14:35.628Z",
      "location_count": 1,
      "location_summary": "Portsmouth, Virginia",
      "locations": [
        {
          "city": "Portsmouth",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01241149"
    },
    {
      "nct_id": "NCT01041105",
      "title": "Gastric Bypass After Previous Anti-reflux Surgery",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Clinically Severe Obesity",
        "Gastroesophageal Reflux Disease"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 22,
      "start_date": "2008-12",
      "completion_date": "2009-12",
      "has_results": false,
      "last_update_posted_date": "2010-01-01",
      "last_synced_at": "2026-09-05T06:14:35.628Z",
      "location_count": 1,
      "location_summary": "Fresno, California",
      "locations": [
        {
          "city": "Fresno",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01041105"
    },
    {
      "nct_id": "NCT01136980",
      "title": "Randomized EsophyX Versus Sham / Placebo Controlled TIF Trial: The RESPECT Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Gastroesophageal Reflux Disease",
        "Hiatal Hernia"
      ],
      "interventions": [
        {
          "name": "TIF Transoral Fundoplication",
          "type": "DEVICE"
        },
        {
          "name": "Sham placebo procedure",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "EndoGastric Solutions",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 129,
      "start_date": "2011-04",
      "completion_date": "2018-03",
      "has_results": true,
      "last_update_posted_date": "2021-12-03",
      "last_synced_at": "2026-09-05T06:14:35.628Z",
      "location_count": 9,
      "location_summary": "Los Angeles, California • Englewood, Colorado • Chicago, Illinois + 5 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Englewood",
          "state": "Colorado"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Columbus",
          "state": "Ohio"
        },
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01136980"
    },
    {
      "nct_id": "NCT00260585",
      "title": "Esophageal Cancer Risk Registry",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Esophageal Cancer",
        "Gastroesophageal Reflux Disease (GERD)",
        "Esophageal Diseases",
        "Hiatal Hernia",
        "Esophageal Achalasia"
      ],
      "interventions": [
        {
          "name": "Survey of client health, personal habits, family history",
          "type": "PROCEDURE"
        },
        {
          "name": "Blood specimen for non-DNA and DNA parts",
          "type": "PROCEDURE"
        },
        {
          "name": "Biopsy of esophageal/stomach tissue, lymph nodes, tumor",
          "type": "PROCEDURE"
        },
        {
          "name": "Biopsies, oral (saliva) and/or secretions, washings or mucosal scrapings/brushing from routine clinical surveillance endoscopies",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 7000,
      "start_date": "1999-06",
      "completion_date": "2050-12",
      "has_results": false,
      "last_update_posted_date": "2026-04-14",
      "last_synced_at": "2026-09-05T06:14:35.628Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00260585"
    }
  ]
}