{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Applanation+Tonometry",
    "query": {
      "intervention": "Applanation Tonometry"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 16,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Applanation+Tonometry&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-02T12:03:43.887Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00227253",
      "title": "Chromosome 18 Clinical Research Center",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Chromosome Aberrations",
        "Growth Hormone Deficiency",
        "Hypomyelination"
      ],
      "interventions": [
        {
          "name": "Determination of growth hormone status",
          "type": "PROCEDURE"
        },
        {
          "name": "Measurement of growth, thyroid and sex hormone levels",
          "type": "PROCEDURE"
        },
        {
          "name": "Behavior and neuropsychometric evaluations",
          "type": "PROCEDURE"
        },
        {
          "name": "Audiological and ear, nose and throat examination",
          "type": "PROCEDURE"
        },
        {
          "name": "Magnetic resonance imaging of the brain",
          "type": "PROCEDURE"
        },
        {
          "name": "Dysmorphology evaluation",
          "type": "PROCEDURE"
        },
        {
          "name": "Neurology examination",
          "type": "PROCEDURE"
        },
        {
          "name": "Dental evaluation",
          "type": "PROCEDURE"
        },
        {
          "name": "Speech pathology evaluation",
          "type": "PROCEDURE"
        },
        {
          "name": "Psychiatric evaluation",
          "type": "PROCEDURE"
        },
        {
          "name": "Orthopedic evaluation",
          "type": "PROCEDURE"
        },
        {
          "name": "Ophthalmologic evaluation",
          "type": "PROCEDURE"
        },
        {
          "name": "Gastrointestinal evaluation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "The University of Texas Health Science Center at San Antonio",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 4000,
      "start_date": "1993-09",
      "completion_date": "2040-12",
      "has_results": false,
      "last_update_posted_date": "2026-01-06",
      "last_synced_at": "2026-09-02T12:03:43.887Z",
      "location_count": 2,
      "location_summary": "San Antonio, Texas",
      "locations": [
        {
          "city": "San Antonio",
          "state": "Texas"
        },
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00227253"
    },
    {
      "nct_id": "NCT02598674",
      "title": "Severe Sepsis in Children - IMPRESS-C",
      "overall_status": "WITHDRAWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Acute Kidney Injury",
        "Chronic Kidney Disease",
        "Hypertension"
      ],
      "interventions": [
        {
          "name": "Iodohippurate",
          "type": "DRUG"
        },
        {
          "name": "24 hour ambulatory Blood Pressure",
          "type": "PROCEDURE"
        },
        {
          "name": "Peripheral Arterial Tonometry",
          "type": "PROCEDURE"
        },
        {
          "name": "Pulse Wave Velocity",
          "type": "PROCEDURE"
        },
        {
          "name": "Gadolinium",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "7 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "7 Years to 17 Years"
      },
      "enrollment_count": 0,
      "start_date": "2019-10",
      "completion_date": "2021-09",
      "has_results": false,
      "last_update_posted_date": "2020-12-09",
      "last_synced_at": "2026-09-02T12:03:43.887Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02598674"
    },
    {
      "nct_id": "NCT01925391",
      "title": "The Measurement of Intraocular Pressure in Normal Children Under General Anesthesia With and Without Nitrous Oxide and Anesthetic Eye Drops",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Glaucoma",
        "Intraocular Pressure",
        "Anesthesia"
      ],
      "interventions": [
        {
          "name": "Tono-pen XL Applanation tonometer + Ocu-film +",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Miami",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "1 Year",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "1 Year to 18 Years"
      },
      "enrollment_count": 75,
      "start_date": "2013-01",
      "completion_date": "2014-05",
      "has_results": false,
      "last_update_posted_date": "2014-06-16",
      "last_synced_at": "2026-09-02T12:03:43.887Z",
      "location_count": 2,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01925391"
    },
    {
      "nct_id": "NCT01141985",
      "title": "New Disposable Contact Lens Patient Interface For The Lensx Laser",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Cataract",
        "Corneal Disease"
      ],
      "interventions": [
        {
          "name": "LenSx Laser modified disposable contact lens",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "LenSx Lasers Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "24 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "24 Years and older"
      },
      "enrollment_count": 110,
      "start_date": "2010-02",
      "completion_date": "2010-12",
      "has_results": false,
      "last_update_posted_date": "2014-10-22",
      "last_synced_at": "2026-09-02T12:03:43.887Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01141985"
    },
    {
      "nct_id": "NCT01786954",
      "title": "iCare vs Tonopen vs Goldmann Applanation Post-vitrectomy Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Intraocular Pressure"
      ],
      "interventions": [
        {
          "name": "Icare rebound tonometry",
          "type": "DEVICE"
        },
        {
          "name": "Tonopen applanation",
          "type": "DEVICE"
        },
        {
          "name": "Goldmann applanation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 68,
      "start_date": "2012-10",
      "completion_date": "2014-09",
      "has_results": true,
      "last_update_posted_date": "2016-05-23",
      "last_synced_at": "2026-09-02T12:03:43.887Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01786954"
    },
    {
      "nct_id": "NCT04708613",
      "title": "University of Pittsburgh Brain Health Initiative",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Traumatic Brain Injury"
      ],
      "interventions": [
        {
          "name": "Cognitive/Neuropsychological Testing",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Vestibular/Ocular-Motor Testing",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Sleep Evaluation",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "MRI, High-Resolution",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Health & Physical Exam",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Physical Function",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Blood Testing and Biomarker Analysis",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Applanation Tonometry",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "PET brain imaging",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "[C-11]6-OH-BTA-1",
          "type": "DRUG"
        },
        {
          "name": "[F-18]AV-1451",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST",
        "DRUG"
      ],
      "sponsor": "David Okonkwo, MD, PhD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "29 Years",
        "maximum_age": "59 Years",
        "sex": "MALE",
        "summary": "29 Years to 59 Years · Male only"
      },
      "enrollment_count": 300,
      "start_date": "2019-11-18",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2026-06-22",
      "last_synced_at": "2026-09-02T12:03:43.887Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04708613"
    },
    {
      "nct_id": "NCT03275142",
      "title": "Icare Tonometry Effects on Keratometry Readings, Topography Readings, and Corneal Staining",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Evaluation of Corneal Stability Post-applanation"
      ],
      "interventions": [
        {
          "name": "Icare tonometer",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Comprehensive EyeCare of Central Ohio",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2017-06-19",
      "completion_date": "2018-07-31",
      "has_results": false,
      "last_update_posted_date": "2019-01-30",
      "last_synced_at": "2026-09-02T12:03:43.887Z",
      "location_count": 1,
      "location_summary": "Westerville, Ohio",
      "locations": [
        {
          "city": "Westerville",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03275142"
    },
    {
      "nct_id": "NCT02416024",
      "title": "Arterial Stiffness and General Anesthesia Induced Hypotension in Patients on Angiotensin-converting Enzyme Inhibitors",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Hypotension",
        "Arterial Stiffness"
      ],
      "interventions": [
        {
          "name": "SphygmoCor system",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Iowa",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "50 Years to 85 Years"
      },
      "enrollment_count": 72,
      "start_date": "2013-08",
      "completion_date": "2018-09",
      "has_results": false,
      "last_update_posted_date": "2019-03-18",
      "last_synced_at": "2026-09-02T12:03:43.887Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02416024"
    },
    {
      "nct_id": "NCT01729273",
      "title": "Vascular Health and Exercise Performance of Overweight Children",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Patient Compliance"
      ],
      "interventions": [
        {
          "name": "Diet and Exercise Intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": "19 Years",
        "sex": "ALL",
        "summary": "10 Years to 19 Years"
      },
      "enrollment_count": 20,
      "start_date": "2012-07",
      "completion_date": "2014-03",
      "has_results": false,
      "last_update_posted_date": "2014-10-06",
      "last_synced_at": "2026-09-02T12:03:43.887Z",
      "location_count": 1,
      "location_summary": "Palo Alto, California",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01729273"
    },
    {
      "nct_id": "NCT05235321",
      "title": "Automated Applanation Tonometry",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Glaucoma",
        "Glaucoma, Suspect"
      ],
      "interventions": [
        {
          "name": "Standard GAT",
          "type": "DEVICE"
        },
        {
          "name": "Fixed force GAT",
          "type": "DEVICE"
        },
        {
          "name": "Upright applanating prototype",
          "type": "DEVICE"
        },
        {
          "name": "Supine Applanating Prototype",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 111,
      "start_date": "2022-11-21",
      "completion_date": "2024-05-31",
      "has_results": false,
      "last_update_posted_date": "2025-06-13",
      "last_synced_at": "2026-09-02T12:03:43.887Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05235321"
    }
  ]
}