{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Apple+Extract&page=5",
    "query": {
      "intervention": "Apple Extract",
      "page": 5
    },
    "page_size": 10
  },
  "pagination": {
    "page": 5,
    "page_size": 10,
    "total_count": 258,
    "total_pages": 26,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Apple+Extract&page=6&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Apple+Extract&page=4&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-23T12:51:41.597Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07124728",
      "title": "Syntrillo Telehealth Stroke Risk Reduction Study",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hypertension",
        "Hypertension (HTN)",
        "Stroke Prevention",
        "Cardiovascular Risk Factor"
      ],
      "interventions": [
        {
          "name": "Technology-enabled Telehealth Care Plan",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Blood Pressure Monitoring Device",
          "type": "DEVICE"
        },
        {
          "name": "Tenovi Smart Pillbox",
          "type": "DEVICE"
        },
        {
          "name": "Wearable Activity Trackers (Fitbit or Apple Watch)",
          "type": "DEVICE"
        },
        {
          "name": "Healthie EHR",
          "type": "OTHER"
        },
        {
          "name": "Secure Messaging Platforms (TigerConnect, Weave, AirCall)",
          "type": "OTHER"
        },
        {
          "name": "Antihypertensive Medication Management",
          "type": "DRUG"
        },
        {
          "name": "Statin Medication Management",
          "type": "DRUG"
        },
        {
          "name": "Antiplatelet or Anticoagulant Therapy",
          "type": "DRUG"
        },
        {
          "name": "Laboratory Blood Test Collection",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DEVICE",
        "OTHER",
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "Syntrillo, Inc",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "30 Years and older"
      },
      "enrollment_count": 11,
      "start_date": "2025-07-30",
      "completion_date": "2026-07-22",
      "has_results": false,
      "last_update_posted_date": "2026-07-30",
      "last_synced_at": "2026-10-23T12:51:41.597Z",
      "location_count": 1,
      "location_summary": "Charlottesville, Virginia",
      "locations": [
        {
          "city": "Charlottesville",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07124728"
    },
    {
      "nct_id": "NCT04182971",
      "title": "Effect of Added Fruit Pomace Fiber, Juice, and Whole Fruit on Postprandial Glycemia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Glycemic Index"
      ],
      "interventions": [
        {
          "name": "Fruit",
          "type": "OTHER"
        },
        {
          "name": "Fruit juice",
          "type": "OTHER"
        },
        {
          "name": "Fruit juice plus fiber",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "PepsiCo Global R&D",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "20 Years to 45 Years"
      },
      "enrollment_count": 58,
      "start_date": "2018-08-28",
      "completion_date": "2019-09-03",
      "has_results": false,
      "last_update_posted_date": "2019-12-05",
      "last_synced_at": "2026-10-23T12:51:41.597Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04182971"
    },
    {
      "nct_id": "NCT06125912",
      "title": "A Comparative Split-Face Study of the Effects of a Retinol Alternative Cream on Improving Facial Skin Aging",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Skin Aging"
      ],
      "interventions": [
        {
          "name": "Dime Beauty TBT Cream",
          "type": "OTHER"
        },
        {
          "name": "Positive Control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Dime Beauty Co.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 65 Years · Female only"
      },
      "enrollment_count": 35,
      "start_date": "2023-09-25",
      "completion_date": "2024-02-15",
      "has_results": false,
      "last_update_posted_date": "2024-02-22",
      "last_synced_at": "2026-10-23T12:51:41.597Z",
      "location_count": 1,
      "location_summary": "Santa Monica, California",
      "locations": [
        {
          "city": "Santa Monica",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06125912"
    },
    {
      "nct_id": "NCT01141595",
      "title": "Tetrahydrobiopterin Treatment in Children With Idiopathic Cognitive Developmental Disorders",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Autism Spectrum Disorder"
      ],
      "interventions": [
        {
          "name": "sapropterin dihydrochloride",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": "6 Years",
        "sex": "ALL",
        "summary": "2 Years to 6 Years"
      },
      "enrollment_count": 10,
      "start_date": "2010-07",
      "completion_date": "2011-09",
      "has_results": true,
      "last_update_posted_date": "2014-04-01",
      "last_synced_at": "2026-10-23T12:51:41.597Z",
      "location_count": 1,
      "location_summary": "Little Rock, Arkansas",
      "locations": [
        {
          "city": "Little Rock",
          "state": "Arkansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01141595"
    },
    {
      "nct_id": "NCT06408181",
      "title": "APPLE: Aspirin to Prevent Pregnancy Loss and Preeclampsia",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Pre-Eclampsia",
        "Pregnancy Loss"
      ],
      "interventions": [
        {
          "name": "Aspirin 162 mg",
          "type": "DRUG"
        },
        {
          "name": "Aspirin 81mg",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 1150,
      "start_date": "2024-06-12",
      "completion_date": "2029-06",
      "has_results": false,
      "last_update_posted_date": "2026-09-10",
      "last_synced_at": "2026-10-23T12:51:41.597Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06408181"
    },
    {
      "nct_id": "NCT03486145",
      "title": "Effect of Nitrate-rich Fruit and Vegetable Supplement on Blood Pressure",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "High Blood Pressure",
        "Flow Mediated Dilation"
      ],
      "interventions": [
        {
          "name": "fruit and vegetable juice supplement",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Arizona State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 57,
      "start_date": "2015-11-16",
      "completion_date": "2016-03-30",
      "has_results": false,
      "last_update_posted_date": "2018-04-03",
      "last_synced_at": "2026-10-23T12:51:41.597Z",
      "location_count": 1,
      "location_summary": "Phoenix, Arizona",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03486145"
    },
    {
      "nct_id": "NCT03182439",
      "title": "Accuracy of Commercially Available Heart Rate Monitors III",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cardiac Rehabilitation"
      ],
      "interventions": [
        {
          "name": "Fit Bit Blaze",
          "type": "DEVICE"
        },
        {
          "name": "Garmin Forerunner 235",
          "type": "DEVICE"
        },
        {
          "name": "Tom Tom Spark Cardio",
          "type": "DEVICE"
        },
        {
          "name": "Apple Watch",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "The Cleveland Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 80,
      "start_date": "2017-06-22",
      "completion_date": "2017-10-11",
      "has_results": false,
      "last_update_posted_date": "2017-10-19",
      "last_synced_at": "2026-10-23T12:51:41.597Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03182439"
    },
    {
      "nct_id": "NCT03705273",
      "title": "Comparison of Dexamethasone Oral Preparations to Assess Taste and Acceptance in Children With Asthma and Croup",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Asthma",
        "Croup"
      ],
      "interventions": [
        {
          "name": "Dexamethasone IV for PO",
          "type": "DRUG"
        },
        {
          "name": "Dexamethasone crushed tablets",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Year",
        "maximum_age": "7 Years",
        "sex": "ALL",
        "summary": "1 Year to 7 Years"
      },
      "enrollment_count": 40,
      "start_date": "2018-10-23",
      "completion_date": "2020-10-02",
      "has_results": true,
      "last_update_posted_date": "2021-11-08",
      "last_synced_at": "2026-10-23T12:51:41.597Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03705273"
    },
    {
      "nct_id": "NCT00272792",
      "title": "Study of Phenoptin to Increase Phenylalanine Tolerance in Phenylketonuric Children on a Phenylalanine-restricted Diet",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Phenylketonurias"
      ],
      "interventions": [
        {
          "name": "Sapropterin Dihydrochloride",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "BioMarin Pharmaceutical",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "4 Years",
        "maximum_age": "12 Years",
        "sex": "ALL",
        "summary": "4 Years to 12 Years"
      },
      "enrollment_count": 45,
      "start_date": "2006-02",
      "completion_date": "2006-11",
      "has_results": true,
      "last_update_posted_date": "2015-08-13",
      "last_synced_at": "2026-10-23T12:51:41.597Z",
      "location_count": 9,
      "location_summary": "Los Angeles, California • Oakland, California • Sacramento, California + 6 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Oakland",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "San Jose",
          "state": "California"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00272792"
    },
    {
      "nct_id": "NCT01725399",
      "title": "Does First Oral Intake After Emergence Predict the Incidence of Post-operative Vomiting in Children?",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Post-operative Vomiting"
      ],
      "interventions": [
        {
          "name": "Apple Juice",
          "type": "OTHER"
        },
        {
          "name": "Water",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "2 Years to 18 Years"
      },
      "enrollment_count": 183,
      "start_date": "2012-10",
      "completion_date": "2013-12",
      "has_results": false,
      "last_update_posted_date": "2014-08-07",
      "last_synced_at": "2026-10-23T12:51:41.597Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01725399"
    }
  ]
}