{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Application+Use&page=42",
    "query": {
      "intervention": "Application Use",
      "page": 42
    },
    "page_size": 10
  },
  "pagination": {
    "page": 42,
    "page_size": 10,
    "total_count": 2608,
    "total_pages": 261,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Application+Use&page=43&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Application+Use&page=41&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-11-12T10:49:34.701Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06360341",
      "title": "Emergency Department Digital Pain Self-Management Intervention to Improve Acute Low Back Pain Outcomes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Low Back Pain, Mechanical",
        "Acute Pain"
      ],
      "interventions": [
        {
          "name": "Emergency Department Digital Pain Self-Management Intervention (EDPSI)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Routine Discharge Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2024-04-15",
      "completion_date": "2024-10-14",
      "has_results": false,
      "last_update_posted_date": "2025-06-27",
      "last_synced_at": "2026-11-12T10:49:34.701Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06360341"
    },
    {
      "nct_id": "NCT00450242",
      "title": "5% Lidocaine Ointment in the Treatment of Vulvar Vestibulitis",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Vulvar Vestibulitis"
      ],
      "interventions": [
        {
          "name": "5% topical lidocaine ointment",
          "type": "DRUG"
        },
        {
          "name": "Placebo cream",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 50 Years · Female only"
      },
      "enrollment_count": 14,
      "start_date": "2006-12",
      "completion_date": "2009-01",
      "has_results": true,
      "last_update_posted_date": "2012-07-16",
      "last_synced_at": "2026-11-12T10:49:34.701Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00450242"
    },
    {
      "nct_id": "NCT01823237",
      "title": "Effect of Increasing Motor Cortex Inhibition on Task Specific Dystonia",
      "overall_status": "SUSPENDED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dystonia"
      ],
      "interventions": [
        {
          "name": "Transcranial Magnetic Stimulation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 15,
      "start_date": "2013-02",
      "completion_date": "2024-02",
      "has_results": false,
      "last_update_posted_date": "2023-08-16",
      "last_synced_at": "2026-11-12T10:49:34.701Z",
      "location_count": 1,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01823237"
    },
    {
      "nct_id": "NCT06873776",
      "title": "Arm and Leg Cycling for Accelerated SCI Recovery",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Spinal Cord Injury"
      ],
      "interventions": [
        {
          "name": "A&L cycling",
          "type": "DEVICE"
        },
        {
          "name": "Body weight supported treadmill training (BWSTT)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Shirley Ryan AbilityLab",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 40,
      "start_date": "2025-12",
      "completion_date": "2032-09",
      "has_results": false,
      "last_update_posted_date": "2025-05-23",
      "last_synced_at": "2026-11-12T10:49:34.701Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06873776"
    },
    {
      "nct_id": "NCT06456268",
      "title": "VibraCool Device to Reduce Pain and Opioid Use After Anterior Cruciate Ligament Reconstruction (ACLR)",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "ACL",
        "Opioid Use",
        "Cryotherapy Effect",
        "Vibration; Exposure",
        "Pain, Postoperative"
      ],
      "interventions": [
        {
          "name": "VibraCool mechanical stimulation and neuromodulatory therapeutic device",
          "type": "DEVICE"
        },
        {
          "name": "Cryocompression (Game Ready, Bregs) device",
          "type": "DEVICE"
        },
        {
          "name": "Standard ice packs",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 130,
      "start_date": "2027-11",
      "completion_date": "2029-11-30",
      "has_results": false,
      "last_update_posted_date": "2026-10-28",
      "last_synced_at": "2026-11-12T10:49:34.701Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06456268"
    },
    {
      "nct_id": "NCT03885791",
      "title": "Randomized Controlled Trial of Vaginal Cryotherapy for Pelvic Floor Myofascial Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pelvic Floor Myofascial Pain",
        "Pelvic Pain",
        "Myofascial Pain"
      ],
      "interventions": [
        {
          "name": "vaginal cryotherapy",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 165,
      "start_date": "2019-03-22",
      "completion_date": "2024-07-24",
      "has_results": false,
      "last_update_posted_date": "2026-02-24",
      "last_synced_at": "2026-11-12T10:49:34.701Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03885791"
    },
    {
      "nct_id": "NCT05573308",
      "title": "Optimizing Orthodontic Appliances Efficiency With Remote Dental Monitoring and Artificial Intelligence Algorithms",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Malocclusion",
        "Misaligned Teeth"
      ],
      "interventions": [
        {
          "name": "Clear Aligners with Dental Monitoring",
          "type": "DEVICE"
        },
        {
          "name": "Clear Aligners",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Illinois Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "12 Years to 70 Years"
      },
      "enrollment_count": 12,
      "start_date": "2022-10-17",
      "completion_date": "2029-12-30",
      "has_results": false,
      "last_update_posted_date": "2026-07-08",
      "last_synced_at": "2026-11-12T10:49:34.701Z",
      "location_count": 4,
      "location_summary": "Antioch, Illinois • Chicago, Illinois • Grayslake, Illinois + 1 more",
      "locations": [
        {
          "city": "Antioch",
          "state": "Illinois"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Grayslake",
          "state": "Illinois"
        },
        {
          "city": "Gurnee",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05573308"
    },
    {
      "nct_id": "NCT06249152",
      "title": "Qlaris Study of QLS-111 in Combination With a PGA for OAG and/or OHT Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Open-angle Glaucoma (OAG)",
        "Ocular Hypertension (OHT)",
        "Glaucoma"
      ],
      "interventions": [
        {
          "name": "QLS-111, 0.015%",
          "type": "DRUG"
        },
        {
          "name": "QLS-111, 0.030%",
          "type": "DRUG"
        },
        {
          "name": "QLS-111, 0.075%",
          "type": "DRUG"
        },
        {
          "name": "QLS-111 vehicle ophthalmic solution",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Qlaris Bio, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "12 Years and older"
      },
      "enrollment_count": 36,
      "start_date": "2024-04-21",
      "completion_date": "2024-12-20",
      "has_results": false,
      "last_update_posted_date": "2025-01-20",
      "last_synced_at": "2026-11-12T10:49:34.701Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06249152"
    },
    {
      "nct_id": "NCT02832115",
      "title": "Topical Nitroglycerine Treatment for Radial Artery Spasm Prevention",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Radial Artery Spasm",
        "Angina",
        "Coronary Artery Disease"
      ],
      "interventions": [
        {
          "name": "Topical Nitroglycerine",
          "type": "DRUG"
        },
        {
          "name": "Topical Lidocaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Aultman Health Foundation",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2016-09",
      "completion_date": "2019-05-02",
      "has_results": true,
      "last_update_posted_date": "2020-10-27",
      "last_synced_at": "2026-11-12T10:49:34.701Z",
      "location_count": 1,
      "location_summary": "Canton, Ohio",
      "locations": [
        {
          "city": "Canton",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02832115"
    },
    {
      "nct_id": "NCT06733506",
      "title": "A Pilot Study to Evaluate Skin Swabbing With Chlorhexidine to Prevent Skin And Soft Tissue Infections Among People Who Inject Drugs",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Opioid Use Disorder",
        "Injection Drug Use",
        "Skin and Soft Tissue Infections (SSTIs)"
      ],
      "interventions": [
        {
          "name": "Chlorhexidine gluconate",
          "type": "DRUG"
        },
        {
          "name": "Isopropyl Alcohol 70% Topical Application Solution",
          "type": "DRUG"
        },
        {
          "name": "Skin Prep Before Injecting Recreational/Street Drugs",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "Gabriel John Culbert",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 56,
      "start_date": "2018-10-01",
      "completion_date": "2019-05-01",
      "has_results": false,
      "last_update_posted_date": "2025-08-03",
      "last_synced_at": "2026-11-12T10:49:34.701Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06733506"
    }
  ]
}