{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Approximation",
    "query": {
      "intervention": "Approximation"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 37,
    "total_pages": 4,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Approximation&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-03T14:24:12.948Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02213510",
      "title": "ZIPS Study - Zip Incision aPproximation vs. Suture",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Wound",
        "Cardiac Arrhythmia"
      ],
      "interventions": [
        {
          "name": "Zip Surgical Skin Closure Device",
          "type": "DEVICE"
        },
        {
          "name": "Standard Suture Closure",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, San Diego",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2014-08",
      "completion_date": "2015-06",
      "has_results": true,
      "last_update_posted_date": "2016-05-30",
      "last_synced_at": "2026-09-03T14:24:12.948Z",
      "location_count": 1,
      "location_summary": "La Jolla, California",
      "locations": [
        {
          "city": "La Jolla",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02213510"
    },
    {
      "nct_id": "NCT02255877",
      "title": "ZIPS Study - Zip Incision Approximation vs. STAPLE",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Arthroplasty, Replacement, Knee"
      ],
      "interventions": [
        {
          "name": "Zip Surgical Skin Closure",
          "type": "DEVICE"
        },
        {
          "name": "Steel Staples",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "ZipLine Medical Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2014-09",
      "completion_date": "2014-09",
      "has_results": false,
      "last_update_posted_date": "2016-10-24",
      "last_synced_at": "2026-09-03T14:24:12.948Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02255877"
    },
    {
      "nct_id": "NCT01410240",
      "title": "Efficacy and Safety of FLOSEAL for Hemostasis in Total Knee Arthroplasty",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Knee Replacement Surgery",
        "Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "Standard of Care",
          "type": "PROCEDURE"
        },
        {
          "name": "FLOSEAL Hemostatic Matrix + Standard of care",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG"
      ],
      "sponsor": "Baxter Healthcare Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 137,
      "start_date": "2011-09",
      "completion_date": "2013-01",
      "has_results": true,
      "last_update_posted_date": "2014-06-06",
      "last_synced_at": "2026-09-03T14:24:12.948Z",
      "location_count": 12,
      "location_summary": "Los Angeles, California • Redwood City, California • Englewood, Colorado + 8 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Redwood City",
          "state": "California"
        },
        {
          "city": "Englewood",
          "state": "Colorado"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "DeLand",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01410240"
    },
    {
      "nct_id": "NCT01294150",
      "title": "The Safety and Effectiveness of UroLift: LIFT Pivotal Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Benign Prostatic Hyperplasia"
      ],
      "interventions": [
        {
          "name": "UroLift System",
          "type": "DEVICE"
        },
        {
          "name": "Cystoscopy",
          "type": "OTHER"
        },
        {
          "name": "Crossover",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "NeoTract, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "MALE",
        "summary": "50 Years and older · Male only"
      },
      "enrollment_count": 206,
      "start_date": "2011-02",
      "completion_date": "2017-07-05",
      "has_results": true,
      "last_update_posted_date": "2018-09-05",
      "last_synced_at": "2026-09-03T14:24:12.948Z",
      "location_count": 14,
      "location_summary": "San Diego, California • San Jose, California • Englewood, Colorado + 11 more",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "San Jose",
          "state": "California"
        },
        {
          "city": "Englewood",
          "state": "Colorado"
        },
        {
          "city": "Daytona Beach",
          "state": "Florida"
        },
        {
          "city": "St. Petersburg",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01294150"
    },
    {
      "nct_id": "NCT00939055",
      "title": "StomaphyX Versus Sham for Revisional Surgery in Post-Roux-en-Y Patients to Reduce Regained Weight",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity"
      ],
      "interventions": [
        {
          "name": "StomaphyX",
          "type": "DEVICE"
        },
        {
          "name": "Sham procedure",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "EndoGastric Solutions",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "18 Years to 64 Years"
      },
      "enrollment_count": 112,
      "start_date": "2009-07",
      "completion_date": "2012-06",
      "has_results": true,
      "last_update_posted_date": "2020-11-23",
      "last_synced_at": "2026-09-03T14:24:12.948Z",
      "location_count": 2,
      "location_summary": "Columbus, Ohio • Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00939055"
    },
    {
      "nct_id": "NCT05288023",
      "title": "Azithromycin for Child Survival in Niger: Programmatic Trial (AVENIR)",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Resistance Bacterial",
        "Morality",
        "Child Health",
        "Implementation"
      ],
      "interventions": [
        {
          "name": "Azithromycin for Oral Suspension",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "1 Month",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "1 Month and older"
      },
      "enrollment_count": 169707,
      "start_date": "2022-12-01",
      "completion_date": "2024-01-15",
      "has_results": true,
      "last_update_posted_date": "2025-03-28",
      "last_synced_at": "2026-09-03T14:24:12.948Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05288023"
    },
    {
      "nct_id": "NCT01345539",
      "title": "Radiosurgery for Patients With Oligometastatic Disease at Initial Presentation",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Oligometastatic Disease"
      ],
      "interventions": [
        {
          "name": "Stereotactic Radiosurgery (SRS)",
          "type": "RADIATION"
        },
        {
          "name": "Chemotherapy",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "RADIATION",
        "DRUG"
      ],
      "sponsor": "Steven Burton",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 24,
      "start_date": "2013-06-07",
      "completion_date": "2022-10-20",
      "has_results": true,
      "last_update_posted_date": "2023-10-11",
      "last_synced_at": "2026-09-03T14:24:12.948Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01345539"
    },
    {
      "nct_id": "NCT03201536",
      "title": "ZipLine Incision Approximation Verses Suture:ZIPS3 Physician Preference Study",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Wounds and Injuries"
      ],
      "interventions": [
        {
          "name": "conventional Suture",
          "type": "DEVICE"
        },
        {
          "name": "Zip3",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "ZipLine Medical Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 0,
      "start_date": "2012-10",
      "completion_date": "2012-10",
      "has_results": false,
      "last_update_posted_date": "2017-06-28",
      "last_synced_at": "2026-09-03T14:24:12.948Z",
      "location_count": 3,
      "location_summary": "Palo Alto, California • San Francisco, California",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03201536"
    },
    {
      "nct_id": "NCT01835405",
      "title": "LiquiBand Versus Dermabond Versus Sutures for Closure of Surgical Wounds",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Surgical Incisions"
      ],
      "interventions": [
        {
          "name": "LiquiBand Flex",
          "type": "DEVICE"
        },
        {
          "name": "Dermabond Advanced",
          "type": "DEVICE"
        },
        {
          "name": "Sutures (Prolene)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Advanced Medical Solutions Ltd.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 66,
      "start_date": "2013-02-20",
      "completion_date": "2014-02-14",
      "has_results": false,
      "last_update_posted_date": "2017-01-24",
      "last_synced_at": "2026-09-03T14:24:12.948Z",
      "location_count": 1,
      "location_summary": "Beverly, Massachusetts",
      "locations": [
        {
          "city": "Beverly",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01835405"
    },
    {
      "nct_id": "NCT01661608",
      "title": "Gastric Restriction Using the EndoSurgical Operating System",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity"
      ],
      "interventions": [
        {
          "name": "Using the EOS for gastric restriction",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "USGI Medical",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "20 Years to 60 Years"
      },
      "enrollment_count": 32,
      "start_date": "2008-12",
      "completion_date": "2010-01",
      "has_results": false,
      "last_update_posted_date": "2012-08-09",
      "last_synced_at": "2026-09-03T14:24:12.948Z",
      "location_count": 4,
      "location_summary": "Lexington, Kentucky • New Orleans, Louisiana • Boston, Massachusetts + 1 more",
      "locations": [
        {
          "city": "Lexington",
          "state": "Kentucky"
        },
        {
          "city": "New Orleans",
          "state": "Louisiana"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Charlotte",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01661608"
    }
  ]
}