{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Ascorbic+Acid+%28Vitamin+C%29&page=5", "query": { "intervention": "Ascorbic Acid (Vitamin C)", "page": 5 }, "page_size": 10 }, "pagination": { "page": 5, "page_size": 10, "total_count": 367, "total_pages": 37, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Ascorbic+Acid+%28Vitamin+C%29&page=6&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Ascorbic+Acid+%28Vitamin+C%29&page=4&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-12T06:08:08.854Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT04335084", "title": "A Study of Hydroxychloroquine, Vitamin C, Vitamin D, and Zinc for the Prevention of COVID-19 Infection", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "COVID-19", "Coronavirus Infection", "Sars-CoV2", "Corona Virus Infection", "COVID", "Coronavirus", "Coronavirus-19", "Coronavirus 19" ], "interventions": [ { "name": "Hydroxychloroquine", "type": "DRUG" }, { "name": "Vitamin C", "type": "DIETARY_SUPPLEMENT" }, { "name": "Vitamin D", "type": "DIETARY_SUPPLEMENT" }, { "name": "Zinc", "type": "DIETARY_SUPPLEMENT" } ], "intervention_types": [ "DRUG", "DIETARY_SUPPLEMENT" ], "sponsor": "ProgenaBiome", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 254, "start_date": "2020-06-22", "completion_date": "2024-04-11", "has_results": false, "last_update_posted_date": "2025-06-05", "last_synced_at": "2026-10-12T06:08:08.854Z", "location_count": 1, "location_summary": "Ventura, California", "locations": [ { "city": "Ventura", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04335084" }, { "nct_id": "NCT01125449", "title": "Study of High Dose Intravenous (IV) Ascorbic Acid in Measurable Solid Tumor Disease", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Sarcoma", "Adenocarcinoma", "Carcinoma", "Multiple Myeloma", "Desmoplastic Small Round Cell Tumor" ], "interventions": [ { "name": "Ascorbic acid (vitamin C)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Situs Cancer Research Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 0, "start_date": "2020-01-01", "completion_date": "2020-06-30", "has_results": false, "last_update_posted_date": "2025-05-18", "last_synced_at": "2026-10-12T06:08:08.854Z", "location_count": 1, "location_summary": "Rogers, Arkansas", "locations": [ { "city": "Rogers", "state": "Arkansas" } ], "official_url": "https://clinicaltrials.gov/study/NCT01125449" }, { "nct_id": "NCT03908333", "title": "High Dose Ascorbic Acid and Nanoparticle Paclitaxel Protein Bound and Cisplatin and Gemcitabine (AA NABPLAGEM) in Patients Who Have Metastatic Pancreatic Cancer", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Metastatic Pancreatic Cancer", "Pancreatic Cancer", "Pancreas Cancer", "Pancreatic Adenocarcinoma Resectable", "Pancreatic Ductal Adenocarcinoma", "Pancreatic Metastasis" ], "interventions": [ { "name": "Ascorbic Acid", "type": "DRUG" }, { "name": "Paclitaxel protein-bound", "type": "DRUG" }, { "name": "Cisplatin", "type": "DRUG" }, { "name": "Gemcitabine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Medical College of Wisconsin", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 0, "start_date": "2019-05-01", "completion_date": "2023-05-01", "has_results": false, "last_update_posted_date": "2019-05-30", "last_synced_at": "2026-10-12T06:08:08.854Z", "location_count": 6, "location_summary": "Scottsdale, Arizona • San Diego, California • Atlanta, Georgia + 3 more", "locations": [ { "city": "Scottsdale", "state": "Arizona" }, { "city": "San Diego", "state": "California" }, { "city": "Atlanta", "state": "Georgia" }, { "city": "Fayetteville", "state": "Georgia" }, { "city": "Newnan", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT03908333" }, { "nct_id": "NCT00954525", "title": "Intravenous Vitamin C in Combination With Standard Chemotherapy for Pancreatic Cancer", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Metastatic Pancreatic Cancer" ], "interventions": [ { "name": "Gemcitabine and Erlotinib", "type": "DRUG" }, { "name": "Intravenous Vitamin C", "type": "DIETARY_SUPPLEMENT" } ], "intervention_types": [ "DRUG", "DIETARY_SUPPLEMENT" ], "sponsor": "Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 14, "start_date": "2009-07", "completion_date": "2011-12", "has_results": false, "last_update_posted_date": "2025-05-02", "last_synced_at": "2026-10-12T06:08:08.854Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT00954525" }, { "nct_id": "NCT02516670", "title": "Docetaxel With or Without Ascorbic Acid in Treating Patients With Metastatic Prostate Cancer", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Hormone-Resistant Prostate Cancer", "Metastatic Prostate Carcinoma", "Stage IV Prostate Cancer" ], "interventions": [ { "name": "Ascorbic Acid", "type": "DIETARY_SUPPLEMENT" }, { "name": "Docetaxel", "type": "DRUG" }, { "name": "Laboratory Biomarker Analysis", "type": "OTHER" }, { "name": "Pharmacological Study", "type": "OTHER" }, { "name": "Placebo", "type": "OTHER" }, { "name": "Quality-of-Life Assessment", "type": "OTHER" } ], "intervention_types": [ "DIETARY_SUPPLEMENT", "DRUG", "OTHER" ], "sponsor": "Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "MALE", "summary": "18 Years and older · Male only" }, "enrollment_count": 50, "start_date": "2016-06-20", "completion_date": "2021-10-14", "has_results": true, "last_update_posted_date": "2023-06-07", "last_synced_at": "2026-10-12T06:08:08.854Z", "location_count": 6, "location_summary": "Washington D.C., District of Columbia • Annapolis, Maryland • Baltimore, Maryland + 3 more", "locations": [ { "city": "Washington D.C.", "state": "District of Columbia" }, { "city": "Annapolis", "state": "Maryland" }, { "city": "Baltimore", "state": "Maryland" }, { "city": "Detroit", "state": "Michigan" }, { "city": "Cleveland", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT02516670" }, { "nct_id": "NCT07227740", "title": "Testosterone Deficiency and Endothelial Dysfunction After Spinal Cord Injury", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Spinal Cord Injuries", "Endothelial Dysfunction", "Testosterone Deficiency" ], "interventions": [ { "name": "Intra-arterial Infusion of Vasoactive Agents", "type": "DIAGNOSTIC_TEST" }, { "name": "Intra-arterial Vitamin C Infusion", "type": "DIAGNOSTIC_TEST" }, { "name": "Blood Sampling", "type": "DIAGNOSTIC_TEST" } ], "intervention_types": [ "DIAGNOSTIC_TEST" ], "sponsor": "Craig Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "89 Years", "sex": "MALE", "summary": "18 Years to 89 Years · Male only" }, "enrollment_count": 48, "start_date": "2025-07-15", "completion_date": "2028-07-14", "has_results": false, "last_update_posted_date": "2025-11-21", "last_synced_at": "2026-10-12T06:08:08.854Z", "location_count": 1, "location_summary": "Englewood, Colorado", "locations": [ { "city": "Englewood", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT07227740" }, { "nct_id": "NCT02818283", "title": "Soy Modulation of Immune Activation, LDL- Levels, and Lowering Inflammation by Pretzel Isoflavone Dietary Intervention", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Human Immunodeficiency Virus (HIV) Infection", "Hypercholesterolemia" ], "interventions": [ { "name": "Soy Pretzel", "type": "DIETARY_SUPPLEMENT" }, { "name": "Wheat Pretzel", "type": "OTHER" } ], "intervention_types": [ "DIETARY_SUPPLEMENT", "OTHER" ], "sponsor": "Ohio State University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1, "start_date": "2016-06", "completion_date": "2023-10", "has_results": false, "last_update_posted_date": "2023-10-06", "last_synced_at": "2026-10-12T06:08:08.854Z", "location_count": 1, "location_summary": "Columbus, Ohio", "locations": [ { "city": "Columbus", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT02818283" }, { "nct_id": "NCT03909789", "title": "Effect of Inorganic Nitrate Supplement on Blood Pressure", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Blood Pressure", "Endothelial Dysfunction" ], "interventions": [ { "name": "Plant based bioequivalent Nitrate supplementation", "type": "DIETARY_SUPPLEMENT" }, { "name": "Placebo", "type": "DIETARY_SUPPLEMENT" } ], "intervention_types": [ "DIETARY_SUPPLEMENT" ], "sponsor": "Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "40 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "40 Years to 75 Years" }, "enrollment_count": 67, "start_date": "2017-11-17", "completion_date": "2018-06-22", "has_results": false, "last_update_posted_date": "2019-04-12", "last_synced_at": "2026-10-12T06:08:08.854Z", "location_count": 1, "location_summary": "Torrance, California", "locations": [ { "city": "Torrance", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03909789" }, { "nct_id": "NCT04437758", "title": "Effects of Hydrolyzed Collagen and Vitamin C on Explosive Performance", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Collagen Synthesis", "Rate of Force (RFD) Development" ], "interventions": [ { "name": "Collagen and Vitamin C powder mix nutritional intervention", "type": "DIETARY_SUPPLEMENT" }, { "name": "Maltodextrin placebo powder", "type": "OTHER" }, { "name": "Maximum power training exercise", "type": "OTHER" } ], "intervention_types": [ "DIETARY_SUPPLEMENT", "OTHER" ], "sponsor": "PepsiCo Global R&D", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "30 Years", "sex": "MALE", "summary": "18 Years to 30 Years · Male only" }, "enrollment_count": 50, "start_date": "2019-08-22", "completion_date": "2020-02-05", "has_results": false, "last_update_posted_date": "2020-06-18", "last_synced_at": "2026-10-12T06:08:08.854Z", "location_count": 1, "location_summary": "Davis, California", "locations": [ { "city": "Davis", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04437758" }, { "nct_id": "NCT00133978", "title": "Trial of Glutamine and Antioxidant Supplementation in Critically Ill Patients", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Critical Illness", "Sepsis", "Multiple Organ Failure" ], "interventions": [ { "name": "Glutamine", "type": "OTHER" }, { "name": "Antioxidants", "type": "OTHER" }, { "name": "Glutamine + Antioxidants", "type": "OTHER" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Daren K. Heyland", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1223, "start_date": "2005-04", "completion_date": "2012-05", "has_results": true, "last_update_posted_date": "2021-01-07", "last_synced_at": "2026-10-12T06:08:08.854Z", "location_count": 5, "location_summary": "Aurora, Colorado • Louisville, Kentucky • Dayton, Ohio + 2 more", "locations": [ { "city": "Aurora", "state": "Colorado" }, { "city": "Louisville", "state": "Kentucky" }, { "city": "Dayton", "state": "Ohio" }, { "city": "Houston", "state": "Texas" }, { "city": "Burlington", "state": "Vermont" } ], "official_url": "https://clinicaltrials.gov/study/NCT00133978" } ] }