{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Azilsartan+medoxomil+%28TAK-491%29", "query": { "intervention": "Azilsartan medoxomil (TAK-491)" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 22, "total_pages": 3, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Azilsartan+medoxomil+%28TAK-491%29&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-10-06T10:18:35.092Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00818883", "title": "Efficacy and Safety of Azilsartan Medoxomil and Chlorthalidone in Participants With Moderate to Severe Hypertension", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Essential Hypertension" ], "interventions": [ { "name": "Azilsartan medoxomil and chlorthalidone", "type": "DRUG" }, { "name": "Azilsartan medoxomil and hydrochlorothiazide", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Takeda", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 609, "start_date": "2009-02", "completion_date": "2009-11", "has_results": true, "last_update_posted_date": "2012-02-07", "last_synced_at": "2026-10-06T10:18:35.092Z", "location_count": 50, "location_summary": "Birmingham, Alabama • Gulf Shores, Alabama • Scottsboro, Alabama + 47 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Gulf Shores", "state": "Alabama" }, { "city": "Scottsboro", "state": "Alabama" }, { "city": "Gilbert", "state": "Arizona" }, { "city": "Sierra Vista", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT00818883" }, { "nct_id": "NCT00591266", "title": "Efficacy and Safety of Azilsartan Medoxomil, Once Daily (QD), Co-Administered With Amlodipine in Participants With Essential Hypertension", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Hypertension" ], "interventions": [ { "name": "Azilsartan Medoxomil and amlodipine", "type": "DRUG" }, { "name": "Amlodipine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Takeda", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 566, "start_date": "2007-10", "completion_date": "2009-04", "has_results": true, "last_update_posted_date": "2011-07-22", "last_synced_at": "2026-10-06T10:18:35.092Z", "location_count": 50, "location_summary": "Mesa, Arizona • Phoenix, Arizona • Anaheim, California + 47 more", "locations": [ { "city": "Mesa", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Anaheim", "state": "California" }, { "city": "Beverly Hills", "state": "California" }, { "city": "Burbank", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00591266" }, { "nct_id": "NCT00591253", "title": "Efficacy and Safety of Azilsartan Medoxomil in African American Participants With Essential Hypertension", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Hypertension" ], "interventions": [ { "name": "Azilsartan medoxomil", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Takeda", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 413, "start_date": "2007-10", "completion_date": "2009-04", "has_results": true, "last_update_posted_date": "2011-04-19", "last_synced_at": "2026-10-06T10:18:35.092Z", "location_count": 60, "location_summary": "Alabaster, Alabama • Huntsville, Alabama • Tempe, Arizona + 57 more", "locations": [ { "city": "Alabaster", "state": "Alabama" }, { "city": "Huntsville", "state": "Alabama" }, { "city": "Tempe", "state": "Arizona" }, { "city": "Freemont", "state": "California" }, { "city": "Garden Grove", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00591253" }, { "nct_id": "NCT07547878", "title": "Rapid and Simultaneous Initiation of Four Guideline-Directed CKD Therapies (RAPID-CKD)", "overall_status": "NOT_YET_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Chronic Kidney Disease", "Type 2 Diabetes" ], "interventions": [ { "name": "Finerenone", "type": "DRUG" }, { "name": "Semaglutide", "type": "DRUG" }, { "name": "Lotensin", "type": "DRUG" }, { "name": "Capoten", "type": "DRUG" }, { "name": "Enalapril", "type": "DRUG" }, { "name": "Monopril", "type": "DRUG" }, { "name": "Lisinopril", "type": "DRUG" }, { "name": "Univasc", "type": "DRUG" }, { "name": "Aceon", "type": "DRUG" }, { "name": "Accupril", "type": "DRUG" }, { "name": "Altace", "type": "DRUG" }, { "name": "Mavik", "type": "DRUG" }, { "name": "Edarbi", "type": "DRUG" }, { "name": "Atacand", "type": "DRUG" }, { "name": "Avapro", "type": "DRUG" }, { "name": "Cozaar", "type": "DRUG" }, { "name": "Benicar", "type": "DRUG" }, { "name": "Micardis", "type": "DRUG" }, { "name": "Diovan", "type": "DRUG" }, { "name": "Invokana", "type": "DRUG" }, { "name": "Farxiga", "type": "DRUG" }, { "name": "Jardiance", "type": "DRUG" }, { "name": "Ertugliflozin", "type": "DRUG" }, { "name": "Brenzavvy", "type": "DRUG" }, { "name": "Sotagliflozin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Baylor Research Institute", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "84 Years", "sex": "ALL", "summary": "18 Years to 84 Years" }, "enrollment_count": 64, "start_date": "2026-04-30", "completion_date": "2029-03-31", "has_results": false, "last_update_posted_date": "2026-05-08", "last_synced_at": "2026-10-06T10:18:35.092Z", "location_count": 1, "location_summary": "Temple, Texas", "locations": [ { "city": "Temple", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT07547878" }, { "nct_id": "NCT00696384", "title": "A Safety and Tolerability Study of Azilsartan Medoxomil in Participants With Essential Hypertension", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Hypertension" ], "interventions": [ { "name": "Azilsartan medoxomil", "type": "DRUG" }, { "name": "Azilsartan medoxomil, with or without chlorthalidone and other non-angiotensin II receptor blocker antihypertensive medications.", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Takeda", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 418, "start_date": "2007-06", "completion_date": "2009-04", "has_results": true, "last_update_posted_date": "2012-01-04", "last_synced_at": "2026-10-06T10:18:35.092Z", "location_count": 33, "location_summary": "Huntsville, Alabama • Chandler, Arizona • Mesa, Arizona + 30 more", "locations": [ { "city": "Huntsville", "state": "Alabama" }, { "city": "Chandler", "state": "Arizona" }, { "city": "Mesa", "state": "Arizona" }, { "city": "Tempe", "state": "Arizona" }, { "city": "Los Gatos", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00696384" }, { "nct_id": "NCT01033071", "title": "Efficacy and Safety of Azilsartan Medoxomil and Chlorthalidone Compared to Olmesartan Medoxomil and Hydrochlorothiazide in Participants With Moderate to Severe Hypertension.", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Essential Hypertension" ], "interventions": [ { "name": "Azilsartan medoxomil and chlorthalidone", "type": "DRUG" }, { "name": "Olmesartan medoxomil and hydrochlorothiazide", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Takeda", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1071, "start_date": "2010-01", "completion_date": "2010-11", "has_results": true, "last_update_posted_date": "2012-02-07", "last_synced_at": "2026-10-06T10:18:35.092Z", "location_count": 84, "location_summary": "Gulf Shores, Alabama • Litchfield Park, Arizona • Mesa, Arizona + 81 more", "locations": [ { "city": "Gulf Shores", "state": "Alabama" }, { "city": "Litchfield Park", "state": "Arizona" }, { "city": "Mesa", "state": "Arizona" }, { "city": "Scottsdale", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT01033071" }, { "nct_id": "NCT00846365", "title": "Efficacy and Safety of Azilsartan Medoxomil Plus Chlorthalidone in Participants With Moderate to Severe Hypertension", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Essential Hypertension" ], "interventions": [ { "name": "Azilsartan medoxomil and chlorthalidone", "type": "DRUG" }, { "name": "Olmesartan medoxomil-hydrochlorothiazide", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Takeda", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1085, "start_date": "2009-03", "completion_date": "2010-06", "has_results": true, "last_update_posted_date": "2012-03-13", "last_synced_at": "2026-10-06T10:18:35.092Z", "location_count": 70, "location_summary": "Birmingham, Alabama • Haleyville, Alabama • Hueytown, Alabama + 67 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Haleyville", "state": "Alabama" }, { "city": "Hueytown", "state": "Alabama" }, { "city": "Jasper", "state": "Alabama" }, { "city": "Tallassee", "state": "Alabama" } ], "official_url": "https://clinicaltrials.gov/study/NCT00846365" }, { "nct_id": "NCT00591773", "title": "Efficacy and Safety of Azilsartan Medoxomil Co-Administered With Chlorthalidone in Participants With Essential Hypertension", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Hypertension" ], "interventions": [ { "name": "Azilsartan medoxomil and chlorthalidone", "type": "DRUG" }, { "name": "Chlorthalidone", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Takeda", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 551, "start_date": "2007-09", "completion_date": "2009-03", "has_results": true, "last_update_posted_date": "2011-04-19", "last_synced_at": "2026-10-06T10:18:35.092Z", "location_count": 46, "location_summary": "Huntsville, Alabama • Montgomery, Alabama • Buena Park, California + 43 more", "locations": [ { "city": "Huntsville", "state": "Alabama" }, { "city": "Montgomery", "state": "Alabama" }, { "city": "Buena Park", "state": "California" }, { "city": "Huntington Beach", "state": "California" }, { "city": "Long Beach", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00591773" }, { "nct_id": "NCT00376181", "title": "Efficacy, Safety and Tolerability of Pioglitazone-Azilsartan in Subjects With Type 2 Diabetes Mellitus", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Type 2 Diabetes" ], "interventions": [ { "name": "Pioglitazone and Azilsartan", "type": "DRUG" }, { "name": "Pioglitazone", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Takeda", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 96, "start_date": "2006-06", "completion_date": "2007-05", "has_results": false, "last_update_posted_date": "2010-06-22", "last_synced_at": "2026-10-06T10:18:35.092Z", "location_count": 59, "location_summary": "Huntsville, Alabama • Tallassee, Alabama • Little Rock, Arkansas + 56 more", "locations": [ { "city": "Huntsville", "state": "Alabama" }, { "city": "Tallassee", "state": "Alabama" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Auburn", "state": "California" }, { "city": "Bakersfield", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00376181" }, { "nct_id": "NCT00362115", "title": "Safety and Efficacy of Azilsartan Medoxomil in Participants With Mild to Moderate Hypertension", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Hypertension" ], "interventions": [ { "name": "Azilsartan Medoxomil", "type": "DRUG" }, { "name": "Olmesartan", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Takeda", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 449, "start_date": "2006-05", "completion_date": "2006-12", "has_results": true, "last_update_posted_date": "2011-04-19", "last_synced_at": "2026-10-06T10:18:35.092Z", "location_count": 46, "location_summary": "Huntsville, Alabama • Ozark, Alabama • Mesa, Arizona + 43 more", "locations": [ { "city": "Huntsville", "state": "Alabama" }, { "city": "Ozark", "state": "Alabama" }, { "city": "Mesa", "state": "Arizona" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Carmichael", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00362115" } ] }