{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=BSS&page=2",
    "query": {
      "intervention": "BSS",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=BSS&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-04T15:50:03.291Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02652767",
      "title": "Efficacy Study of GS010 for the Treatment of Vision Loss up to 6 Months From Onset in LHON Due to the ND4 Mutation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Optic, Atrophy, Hereditary, Leber"
      ],
      "interventions": [
        {
          "name": "GS010",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Sham Intravitreal Injection",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "DEVICE"
      ],
      "sponsor": "GenSight Biologics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "15 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "15 Years and older"
      },
      "enrollment_count": 39,
      "start_date": "2016-02-23",
      "completion_date": "2019-07-04",
      "has_results": true,
      "last_update_posted_date": "2026-03-02",
      "last_synced_at": "2026-09-04T15:50:03.291Z",
      "location_count": 3,
      "location_summary": "Los Angeles, California • Atlanta, Georgia • Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02652767"
    },
    {
      "nct_id": "NCT05794100",
      "title": "Evaluating the Impact of Different Sugar Replacer Combinations on Gastrointestinal Tolerance",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tolerance",
        "Healthy Population"
      ],
      "interventions": [
        {
          "name": "Acute intake of one of the products (active comparator 1 to 9) or Placebo comparator",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Mondelēz International, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 60,
      "start_date": "2021-10-11",
      "completion_date": "2022-07-30",
      "has_results": false,
      "last_update_posted_date": "2023-04-03",
      "last_synced_at": "2026-09-04T15:50:03.291Z",
      "location_count": 1,
      "location_summary": "Addison, Illinois",
      "locations": [
        {
          "city": "Addison",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05794100"
    },
    {
      "nct_id": "NCT03535272",
      "title": "Bismuth Subsalicylate's Role in the Prevention of Travelers' Diarrhea",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Diarrhea Travelers",
        "Antibiotic Resistant Infection"
      ],
      "interventions": [
        {
          "name": "Bismuth subsalicylate",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Centers for Disease Control and Prevention",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "69 Years",
        "sex": "ALL",
        "summary": "18 Years to 69 Years"
      },
      "enrollment_count": 482,
      "start_date": "2018-05-20",
      "completion_date": "2026-04-29",
      "has_results": true,
      "last_update_posted_date": "2026-05-22",
      "last_synced_at": "2026-09-04T15:50:03.291Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03535272"
    },
    {
      "nct_id": "NCT02652780",
      "title": "Efficacy Study of GS010 for Treatment of Vision Loss From 7 Months to 1 Year From Onset in LHON Due to the ND4 Mutation (REVERSE)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Optic, Atrophy, Hereditary, Leber"
      ],
      "interventions": [
        {
          "name": "GS010",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Sham Intravitreal Injection",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "DEVICE"
      ],
      "sponsor": "GenSight Biologics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "15 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "15 Years and older"
      },
      "enrollment_count": 37,
      "start_date": "2016-01",
      "completion_date": "2018-12",
      "has_results": true,
      "last_update_posted_date": "2026-03-02",
      "last_synced_at": "2026-09-04T15:50:03.291Z",
      "location_count": 3,
      "location_summary": "Los Angeles, California • Atlanta, Georgia • Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02652780"
    },
    {
      "nct_id": "NCT04945850",
      "title": "Can COVID-19 Persist in Intraocular Fluid?",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Ocular Infection, Viral"
      ],
      "interventions": [
        {
          "name": "routine care intraocular sx",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 25,
      "start_date": "2021-06-16",
      "completion_date": "2022-06-16",
      "has_results": false,
      "last_update_posted_date": "2024-09-23",
      "last_synced_at": "2026-09-04T15:50:03.291Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04945850"
    },
    {
      "nct_id": "NCT00798577",
      "title": "Study of the Progression of Bacterial Conjunctivitis Symptoms Upon Antibiotic Treatment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Bacterial Conjunctivitis"
      ],
      "interventions": [
        {
          "name": "Vigamox Ophthalmic Solution",
          "type": "DRUG"
        },
        {
          "name": "BSS placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Year",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "1 Year and older"
      },
      "enrollment_count": 24,
      "start_date": "2008-10",
      "completion_date": "2009-02",
      "has_results": true,
      "last_update_posted_date": "2010-03-31",
      "last_synced_at": "2026-09-04T15:50:03.291Z",
      "location_count": 1,
      "location_summary": "Fort Worth, Texas",
      "locations": [
        {
          "city": "Fort Worth",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00798577"
    },
    {
      "nct_id": "NCT00346528",
      "title": "Safety of NGOIS Compared to BSS Plus in Pediatric Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Cataract"
      ],
      "interventions": [
        {
          "name": "Next Generation Ophthalmic Irrigating Solution (NGOIS)",
          "type": "DRUG"
        },
        {
          "name": "BSS Plus",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Week",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "1 Week to 17 Years"
      },
      "enrollment_count": 18,
      "start_date": "2006-07",
      "completion_date": "2007-06",
      "has_results": false,
      "last_update_posted_date": "2012-03-05",
      "last_synced_at": "2026-09-04T15:50:03.291Z",
      "location_count": 1,
      "location_summary": "Fort Worth, Texas",
      "locations": [
        {
          "city": "Fort Worth",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00346528"
    },
    {
      "nct_id": "NCT05930197",
      "title": "Effect of Bismuth Subsalicylate on the Gut Microbiome and Host Response in Healthy Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Healthy Adults"
      ],
      "interventions": [
        {
          "name": "Bismuth subsalicylate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 34,
      "start_date": "2023-08-31",
      "completion_date": "2024-12-15",
      "has_results": true,
      "last_update_posted_date": "2026-03-24",
      "last_synced_at": "2026-09-04T15:50:03.291Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05930197"
    },
    {
      "nct_id": "NCT02988596",
      "title": "Role of Rehabilitation in Concussion Management: A Randomized Controlled Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Concussion, Brain"
      ],
      "interventions": [
        {
          "name": "Multidimensional Active Rehabilitation",
          "type": "OTHER"
        },
        {
          "name": "Enhanced Graded Exertion",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "13 Years to 99 Years"
      },
      "enrollment_count": 251,
      "start_date": "2017-01",
      "completion_date": "2019-08",
      "has_results": false,
      "last_update_posted_date": "2021-07-30",
      "last_synced_at": "2026-09-04T15:50:03.291Z",
      "location_count": 7,
      "location_summary": "Durham, North Carolina • Elon, North Carolina • Hillsborough, North Carolina + 4 more",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        },
        {
          "city": "Elon",
          "state": "North Carolina"
        },
        {
          "city": "Hillsborough",
          "state": "North Carolina"
        },
        {
          "city": "Pittsboro",
          "state": "North Carolina"
        },
        {
          "city": "Salisbury",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02988596"
    },
    {
      "nct_id": "NCT07020728",
      "title": "Clarity in Motion Phase-1 Perceptual Study of Speech Intelligibility",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "Solo: Unmasked Speech Stimuli",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Raw: Fully masked speech--no motion stimuli",
          "type": "BEHAVIORAL"
        },
        {
          "name": "StatScrub: Extracted Speech--no motion stimuli",
          "type": "BEHAVIORAL"
        },
        {
          "name": "SlideSpch: Scrubbed Speech emitted from linearly moving speaker stimuli",
          "type": "BEHAVIORAL"
        },
        {
          "name": "SlideNoise: Speech Scrubbed from linearly moving and stationary noise stimuli",
          "type": "BEHAVIORAL"
        },
        {
          "name": "SlideMic: Stationary sources scrubbed from a linearly moving mic stimuli",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Speech Technology and Applied Research Corp.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 72,
      "start_date": "2024-08-01",
      "completion_date": "2024-08-31",
      "has_results": false,
      "last_update_posted_date": "2025-06-25",
      "last_synced_at": "2026-09-04T15:50:03.291Z",
      "location_count": 1,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07020728"
    }
  ]
}