{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Baclofen+5+mg",
    "query": {
      "intervention": "Baclofen 5 mg"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 9,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-20T00:41:35.277Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04251819",
      "title": "Buprenorphine Plus Baclofen to Increase Analgesia in Healthy Volunteers",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Acute Pain",
        "Analgesia"
      ],
      "interventions": [
        {
          "name": "Placebos",
          "type": "DRUG"
        },
        {
          "name": "Baclofen 5 mg",
          "type": "DRUG"
        },
        {
          "name": "Baclofen 10mg",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 19,
      "start_date": "2021-01-21",
      "completion_date": "2024-06-15",
      "has_results": true,
      "last_update_posted_date": "2026-01-07",
      "last_synced_at": "2026-09-20T00:41:35.277Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04251819"
    },
    {
      "nct_id": "NCT01013480",
      "title": "An Open Label Extension Study of STX209 in Subjects With Fragile X Syndrome",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Fragile X Syndrome"
      ],
      "interventions": [
        {
          "name": "Arbaclofen",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Seaside Therapeutics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "6 Years to 40 Years"
      },
      "enrollment_count": 45,
      "start_date": "2009-11",
      "completion_date": "2012-12",
      "has_results": false,
      "last_update_posted_date": "2012-12-20",
      "last_synced_at": "2026-09-20T00:41:35.277Z",
      "location_count": 9,
      "location_summary": "Los Angeles, California • Sacramento, California • Chicago, Illinois + 6 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Staten Island",
          "state": "New York"
        },
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01013480"
    },
    {
      "nct_id": "NCT01325220",
      "title": "Efficacy and Safety Study of STX209 (Arbaclofen) for the Treatment of Social Withdrawal in Children With Fragile X Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Fragile X Syndrome"
      ],
      "interventions": [
        {
          "name": "arbaclofen",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Seaside Therapeutics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": "11 Years",
        "sex": "ALL",
        "summary": "5 Years to 11 Years"
      },
      "enrollment_count": 172,
      "start_date": "2011-06",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2013-07-31",
      "last_synced_at": "2026-09-20T00:41:35.277Z",
      "location_count": 28,
      "location_summary": "Phoenix, Arizona • Long Beach, California • Sacramento, California + 24 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Long Beach",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01325220"
    },
    {
      "nct_id": "NCT06274021",
      "title": "Neuromodulation to Reduce Muscle Stiffness Following Spinal Cord Injury",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Spinal Cord Injuries",
        "Spinal Cord Injury",
        "Spinal Cord Injury Cervical",
        "Spinal Cord Injury Thoracic"
      ],
      "interventions": [
        {
          "name": "Transcutaneous spinal stimulation at 100 Hz",
          "type": "DEVICE"
        },
        {
          "name": "Transcutaneous spinal stimulation at 50 Hz",
          "type": "DEVICE"
        },
        {
          "name": "Transcutaneous spinal stimulation at 50 Hz and single dose of baclofen",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Transcutaneous spinal stimulation at 50 Hz and single dose of tizanidine",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Sham transcutaneous spinal stimulation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "University of Mississippi Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 16,
      "start_date": "2024-03-01",
      "completion_date": "2025-12-31",
      "has_results": false,
      "last_update_posted_date": "2024-07-01",
      "last_synced_at": "2026-09-20T00:41:35.277Z",
      "location_count": 2,
      "location_summary": "Jackson, Mississippi",
      "locations": [
        {
          "city": "Jackson",
          "state": "Mississippi"
        },
        {
          "city": "Jackson",
          "state": "Mississippi"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06274021"
    },
    {
      "nct_id": "NCT07792616",
      "title": "Electrical Neuromodulation for Modifying Spinal Network Involved in Spasticity",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Spinal Cord Injuries (Complete and Incomplete)",
        "Spinal Cord Injury",
        "Spinal Cord Injury Cervical",
        "Spinal Cord Injury Thoracic",
        "Spinal Cord Injuries",
        "Spasticity",
        "Spasm",
        "Muscle Spasticity",
        "Muscle Hypertonia",
        "Muscle Spasm"
      ],
      "interventions": [
        {
          "name": "Transcutaneous spinal stimulation at 30 Hz",
          "type": "OTHER"
        },
        {
          "name": "Transcutaneous spinal stimulation at 75 Hz",
          "type": "OTHER"
        },
        {
          "name": "Tizanidine",
          "type": "DRUG"
        },
        {
          "name": "Baclofen",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DRUG"
      ],
      "sponsor": "University of Mississippi Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 12,
      "start_date": "2022-07-13",
      "completion_date": "2027-07-14",
      "has_results": false,
      "last_update_posted_date": "2026-08-28",
      "last_synced_at": "2026-09-20T00:41:35.277Z",
      "location_count": 2,
      "location_summary": "Jackson, Mississippi",
      "locations": [
        {
          "city": "Jackson",
          "state": "Mississippi"
        },
        {
          "city": "Jackson",
          "state": "Mississippi"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07792616"
    },
    {
      "nct_id": "NCT03023540",
      "title": "Assessing Long Term Safety and Tolerability of PXT3003 in Patients With Charcot-Marie-Tooth Disease Type 1A",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Charcot-Marie-Tooth Disease, Type IA"
      ],
      "interventions": [
        {
          "name": "PXT3003",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Pharnext S.C.A.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "17 Years",
        "maximum_age": "67 Years",
        "sex": "ALL",
        "summary": "17 Years to 67 Years"
      },
      "enrollment_count": 187,
      "start_date": "2017-03-07",
      "completion_date": "2024-12-31",
      "has_results": false,
      "last_update_posted_date": "2024-02-20",
      "last_synced_at": "2026-09-20T00:41:35.277Z",
      "location_count": 9,
      "location_summary": "Los Angeles, California • Gainesville, Florida • Kansas City, Kansas + 6 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Kansas City",
          "state": "Kansas"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03023540"
    },
    {
      "nct_id": "NCT00914290",
      "title": "A Study With IPX056 in Subjects With Spasticity Associated With Multiple Sclerosis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Spasticity",
        "Multiple Sclerosis"
      ],
      "interventions": [
        {
          "name": "IPX056",
          "type": "DRUG"
        },
        {
          "name": "Baclofen IR",
          "type": "DRUG"
        },
        {
          "name": "Placebo IPX056",
          "type": "DRUG"
        },
        {
          "name": "Placebo IR",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Impax Laboratories, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 23,
      "start_date": "2009-04",
      "completion_date": "2010-02",
      "has_results": false,
      "last_update_posted_date": "2019-11-06",
      "last_synced_at": "2026-09-20T00:41:35.277Z",
      "location_count": 11,
      "location_summary": "Tucson, Arizona • Aurora, Colorado • Tampa, Florida + 8 more",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "Fort Wayne",
          "state": "Indiana"
        },
        {
          "city": "Lenexa",
          "state": "Kansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00914290"
    },
    {
      "nct_id": "NCT01064973",
      "title": "An Open Label Extension Study of STX209 in Subjects With Autism Spectrum Disorders",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Autism Spectrum Disorders"
      ],
      "interventions": [
        {
          "name": "arbaclofen",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Seaside Therapeutics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "6 Years to 17 Years"
      },
      "enrollment_count": 32,
      "start_date": "2010-02",
      "completion_date": "2012-12",
      "has_results": false,
      "last_update_posted_date": "2012-12-20",
      "last_synced_at": "2026-09-20T00:41:35.277Z",
      "location_count": 8,
      "location_summary": "Phoenix, Arizona • Los Angeles, California • New Haven, Connecticut + 5 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01064973"
    },
    {
      "nct_id": "NCT01265550",
      "title": "A Randomized Trial of Medical and Surgical Treatments for Patients With GERD Symptoms That Are Refractory to Proton Pump Inhibitors",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "GERD"
      ],
      "interventions": [
        {
          "name": "Nissen fundoplication",
          "type": "DEVICE"
        },
        {
          "name": "baclofen",
          "type": "DRUG"
        },
        {
          "name": "Desipramine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "18 Years to 64 Years"
      },
      "enrollment_count": 366,
      "start_date": "2012-08-13",
      "completion_date": "2016-12-30",
      "has_results": true,
      "last_update_posted_date": "2020-01-22",
      "last_synced_at": "2026-09-20T00:41:35.277Z",
      "location_count": 15,
      "location_summary": "Birmingham, Alabama • Tucson, Arizona • Loma Linda, California + 12 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Loma Linda",
          "state": "California"
        },
        {
          "city": "Long Beach",
          "state": "California"
        },
        {
          "city": "West Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01265550"
    }
  ]
}