{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Bardoxolone+Methyl", "query": { "intervention": "Bardoxolone Methyl" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 22, "total_pages": 3, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Bardoxolone+Methyl&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-15T22:48:03.051Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT01503866", "title": "A Phase I Study to Investigate the Absorption, Metabolism and Excretion in Healthy Male Subjects", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Healthy" ], "interventions": [ { "name": "bardoxolone methyl", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Biogen", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "45 Years", "sex": "MALE", "summary": "18 Years to 45 Years · Male only" }, "enrollment_count": 6, "start_date": "2011-12-01", "completion_date": "2011-12-31", "has_results": false, "last_update_posted_date": "2025-05-29", "last_synced_at": "2026-09-15T22:48:03.051Z", "location_count": 1, "location_summary": "Madison, Wisconsin", "locations": [ { "city": "Madison", "state": "Wisconsin" } ], "official_url": "https://clinicaltrials.gov/study/NCT01503866" }, { "nct_id": "NCT00529113", "title": "Study With Gemcitabine and RTA 402 for Patients With Unresectable Pancreatic Cancer", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Pancreatic Neoplasms", "Pancreatic Cancer" ], "interventions": [ { "name": "Bardoxolone methyl", "type": "DRUG" }, { "name": "Gemcitabine", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Biogen", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 33, "start_date": "2007-09-30", "completion_date": "2009-11-01", "has_results": false, "last_update_posted_date": "2025-05-29", "last_synced_at": "2026-09-15T22:48:03.051Z", "location_count": 5, "location_summary": "Denver, Colorado • Ocoee, Florida • Indianapolis, Indiana + 2 more", "locations": [ { "city": "Denver", "state": "Colorado" }, { "city": "Ocoee", "state": "Florida" }, { "city": "Indianapolis", "state": "Indiana" }, { "city": "Dallas", "state": "Texas" }, { "city": "Vancouver", "state": "Washington" } ], "official_url": "https://clinicaltrials.gov/study/NCT00529113" }, { "nct_id": "NCT04494646", "title": "BARCONA: A Study of Effects of Bardoxolone Methyl in Participants With SARS-Corona Virus-2 (COVID-19)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Covid19" ], "interventions": [ { "name": "Bardoxolone Methyl", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "NYU Langone Health", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 40, "start_date": "2020-09-08", "completion_date": "2021-01-08", "has_results": true, "last_update_posted_date": "2022-01-13", "last_synced_at": "2026-09-15T22:48:03.051Z", "location_count": 8, "location_summary": "Springfield, Illinois • Brooklyn, New York • Elmhurst, New York + 2 more", "locations": [ { "city": "Springfield", "state": "Illinois" }, { "city": "Springfield", "state": "Illinois" }, { "city": "Brooklyn", "state": "New York" }, { "city": "Brooklyn", "state": "New York" }, { "city": "Elmhurst", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT04494646" }, { "nct_id": "NCT04702997", "title": "A Trial of Bardoxolone Methyl in Patients With CKD at Risk of Rapid Progression (MERLIN)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Chronic Kidney Diseases" ], "interventions": [ { "name": "Bardoxolone methyl oral capsule", "type": "DRUG" }, { "name": "Placebo oral capsule", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Biogen", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 81, "start_date": "2021-02-09", "completion_date": "2021-11-23", "has_results": true, "last_update_posted_date": "2025-06-03", "last_synced_at": "2026-09-15T22:48:03.051Z", "location_count": 12, "location_summary": "La Mesa, California • Arvada, Colorado • Denver, Colorado + 9 more", "locations": [ { "city": "La Mesa", "state": "California" }, { "city": "Arvada", "state": "Colorado" }, { "city": "Denver", "state": "Colorado" }, { "city": "Nampa", "state": "Idaho" }, { "city": "Baton Rouge", "state": "Louisiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT04702997" }, { "nct_id": "NCT01598363", "title": "An Open-Label Study of the Effect of Bardoxolone Methyl on the Single Dose Pharmacokinetics of Digoxin and Rosuvastatin in Healthy Volunteers", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Healthy Volunteers" ], "interventions": [ { "name": "Digoxin", "type": "DRUG" }, { "name": "Rosuvastatin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Biogen", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "45 Years", "sex": "ALL", "summary": "18 Years to 45 Years" }, "enrollment_count": 32, "start_date": "2012-06-30", "completion_date": "2012-07-31", "has_results": false, "last_update_posted_date": "2025-05-29", "last_synced_at": "2026-09-15T22:48:03.051Z", "location_count": 1, "location_summary": "West Bend, Wisconsin", "locations": [ { "city": "West Bend", "state": "Wisconsin" } ], "official_url": "https://clinicaltrials.gov/study/NCT01598363" }, { "nct_id": "NCT01053936", "title": "Phase II Pharmacodynamic Trial to Determine the Effects of Bardoxolone Methyl on eGFR in Patients With Type 2 Diabetes and Chronic Kidney Disease", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Renal Insufficiency, Chronic", "Diabetes Mellitus, Type 2" ], "interventions": [ { "name": "Bardoxolone methyl (amorphous dispersion)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Biogen", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 129, "start_date": "2010-01-31", "completion_date": "2011-02-28", "has_results": false, "last_update_posted_date": "2025-05-29", "last_synced_at": "2026-09-15T22:48:03.051Z", "location_count": 26, "location_summary": "Montgomery, Alabama • Phoenix, Arizona • Tempe, Arizona + 23 more", "locations": [ { "city": "Montgomery", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Tempe", "state": "Arizona" }, { "city": "La Mesa", "state": "California" }, { "city": "Riverside", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01053936" }, { "nct_id": "NCT03366337", "title": "A Phase 2 Trial of the Safety and Efficacy of Bardoxolone Methyl in Patients With Rare Chronic Kidney Diseases - PHOENIX", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "IgA Nephropathy", "CKD Associated With Type 1 Diabetes", "Focal Segmental Glomerulosclerosis", "Autosomal Dominant Polycystic Kidney" ], "interventions": [ { "name": "Bardoxolone methyl capsules", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Biogen", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 103, "start_date": "2017-12-26", "completion_date": "2019-01-29", "has_results": true, "last_update_posted_date": "2025-06-03", "last_synced_at": "2026-09-15T22:48:03.051Z", "location_count": 30, "location_summary": "Birmingham, Alabama • Phoenix, Arizona • Los Angeles, California + 27 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Los Angeles", "state": "California" }, { "city": "Denver", "state": "Colorado" }, { "city": "Clearwater", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT03366337" }, { "nct_id": "NCT02036970", "title": "Bardoxolone Methyl Evaluation in Patients With Pulmonary Hypertension (PH) - LARIAT", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Pulmonary Arterial Hypertension", "Pulmonary Hypertension", "Interstitial Lung Disease", "Idiopathic Interstitial Pneumonia", "Idiopathic Pulmonary Fibrosis", "Sarcoidosis", "Respiratory Bronchiolitis Associated Interstitial Lung Disease", "Desquamative Interstitial Pneumonia", "Cryptogenic Organizing Pneumonia", "Acute Interstitial Pneumonitis", "Idiopathic Lymphoid Interstitial Pneumonia", "Idiopathic Pleuroparenchymal Fibroelastosis" ], "interventions": [ { "name": "Bardoxolone methyl", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Biogen", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 166, "start_date": "2014-05-31", "completion_date": "2018-05-16", "has_results": true, "last_update_posted_date": "2025-06-10", "last_synced_at": "2026-09-15T22:48:03.051Z", "location_count": 30, "location_summary": "Phoenix, Arizona • Beverly Hills, California • Los Angeles, California + 20 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Beverly Hills", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Sacramento", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02036970" }, { "nct_id": "NCT01689116", "title": "Multiple-Dose Study of Effect of Bardoxolone Methyl on QT/QTC Interval Volunteers", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Healthy Volunteers" ], "interventions": [ { "name": "Bardoxolone Methyl 20mg", "type": "DRUG" }, { "name": "Bardoxolone Methyl 80mg", "type": "DRUG" }, { "name": "Bardoxolone Methyl Placebo", "type": "DRUG" }, { "name": "Moxifloxacin 400mg", "type": "DRUG" }, { "name": "Moxifloxacin Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Biogen", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "50 Years", "sex": "ALL", "summary": "18 Years to 50 Years" }, "enrollment_count": 179, "start_date": "2012-08-31", "completion_date": "2012-11-30", "has_results": false, "last_update_posted_date": "2025-05-29", "last_synced_at": "2026-09-15T22:48:03.051Z", "location_count": 1, "location_summary": "West Bend, Wisconsin", "locations": [ { "city": "West Bend", "state": "Wisconsin" } ], "official_url": "https://clinicaltrials.gov/study/NCT01689116" }, { "nct_id": "NCT03068130", "title": "Extended Access Program to Assess Long-term Safety of Bardoxolone Methyl in Patients With Pulmonary Hypertension RANGER", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Pulmonary Hypertension" ], "interventions": [ { "name": "Bardoxolone methyl", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Biogen", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "18 Years to 85 Years" }, "enrollment_count": 261, "start_date": "2017-04-18", "completion_date": "2020-09-30", "has_results": true, "last_update_posted_date": "2025-06-11", "last_synced_at": "2026-09-15T22:48:03.051Z", "location_count": 46, "location_summary": "Phoenix, Arizona • Beverly Hills, California • La Jolla, California + 32 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Beverly Hills", "state": "California" }, { "city": "La Jolla", "state": "California" }, { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03068130" } ] }