{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Barzolvolimab", "query": { "intervention": "Barzolvolimab" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 10, "total_pages": 1, "next_page_url": null, "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-02T10:50:49.680Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT05368285", "title": "A Phase 2 Study of CDX-0159 in Patients With Chronic Spontaneous Urticaria", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Chronic Spontaneous Urticaria" ], "interventions": [ { "name": "barzolvolimab", "type": "BIOLOGICAL" }, { "name": "Matching Placebo", "type": "DRUG" } ], "intervention_types": [ "BIOLOGICAL", "DRUG" ], "sponsor": "Celldex Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 208, "start_date": "2022-05-19", "completion_date": "2024-12-20", "has_results": false, "last_update_posted_date": "2025-03-26", "last_synced_at": "2026-09-02T10:50:49.680Z", "location_count": 13, "location_summary": "Birmingham, Alabama • Scottsdale, Arizona • Little Rock, Arkansas + 10 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Scottsdale", "state": "Arizona" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Bakersfield", "state": "California" }, { "city": "Redwood City", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT05368285" }, { "nct_id": "NCT06455202", "title": "A Phase 3 Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria (CSU)", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Chronic Spontaneous Urticaria" ], "interventions": [ { "name": "barzolvolimab", "type": "BIOLOGICAL" }, { "name": "Matching placebo", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Celldex Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 976, "start_date": "2024-07-19", "completion_date": "2027-04", "has_results": false, "last_update_posted_date": "2026-03-25", "last_synced_at": "2026-09-02T10:50:49.680Z", "location_count": 63, "location_summary": "Cullman, Alabama • Litchfield Park, Arizona • Scottsdale, Arizona + 47 more", "locations": [ { "city": "Cullman", "state": "Alabama" }, { "city": "Litchfield Park", "state": "Arizona" }, { "city": "Scottsdale", "state": "Arizona" }, { "city": "Scottsdale", "state": "Arizona" }, { "city": "Bakersfield", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06455202" }, { "nct_id": "NCT06727552", "title": "A Study of Barzolvolimab in Patients With Atopic Dermatitis", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Atopic Dermatitis" ], "interventions": [ { "name": "Barzolvolimab", "type": "BIOLOGICAL" }, { "name": "Matching placebo", "type": "DRUG" } ], "intervention_types": [ "BIOLOGICAL", "DRUG" ], "sponsor": "Celldex Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 131, "start_date": "2024-12-18", "completion_date": "2026-12", "has_results": false, "last_update_posted_date": "2026-08-11", "last_synced_at": "2026-09-02T10:50:49.680Z", "location_count": 33, "location_summary": "Birmingham, Alabama • Beverly Hills, California • Burbank, California + 28 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Beverly Hills", "state": "California" }, { "city": "Burbank", "state": "California" }, { "city": "Inglewood", "state": "California" }, { "city": "Laguna Niguel", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06727552" }, { "nct_id": "NCT07256392", "title": "Long-term Efficacy and Safety Extension (LTE) Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria", "overall_status": "ENROLLING_BY_INVITATION", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Chronic Spontaneous Urticaria" ], "interventions": [ { "name": "barzolvolimab", "type": "BIOLOGICAL" }, { "name": "Standard of Care", "type": "OTHER" } ], "intervention_types": [ "BIOLOGICAL", "OTHER" ], "sponsor": "Celldex Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1370, "start_date": "2025-11-25", "completion_date": "2028-09", "has_results": false, "last_update_posted_date": "2026-08-27", "last_synced_at": "2026-09-02T10:50:49.680Z", "location_count": 39, "location_summary": "Birmingham, Alabama • Scottsdale, Arizona • Bakersfield, California + 32 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Scottsdale", "state": "Arizona" }, { "city": "Scottsdale", "state": "Arizona" }, { "city": "Bakersfield", "state": "California" }, { "city": "Laguna Niguel", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT07256392" }, { "nct_id": "NCT04944862", "title": "A Study of CDX-0159 in Patients With Prurigo Nodularis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Prurigo Nodularis" ], "interventions": [ { "name": "CDX-0159", "type": "BIOLOGICAL" }, { "name": "Normal saline", "type": "DRUG" } ], "intervention_types": [ "BIOLOGICAL", "DRUG" ], "sponsor": "Celldex Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 24, "start_date": "2021-11-08", "completion_date": "2023-07-31", "has_results": false, "last_update_posted_date": "2023-08-14", "last_synced_at": "2026-09-02T10:50:49.680Z", "location_count": 7, "location_summary": "Tempe, Arizona • Miami, Florida • Troy, Michigan + 4 more", "locations": [ { "city": "Tempe", "state": "Arizona" }, { "city": "Miami", "state": "Florida" }, { "city": "Troy", "state": "Michigan" }, { "city": "Albuquerque", "state": "New Mexico" }, { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT04944862" }, { "nct_id": "NCT07266402", "title": "A Study to Investigate Efficacy, Safety and Tolerability of Barzolvolimab Versus Placebo in Adults With Cold Induced Urticaria and Symptomatic Dermographism Inadequately Controlled by H1-antihistamines (EMBARQ - ColdU and SD)", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Chronic Inducible Urticaria", "Cold Urticaria", "Cold-Induced Urticaria", "Symptomatic Dermographism" ], "interventions": [ { "name": "Barzolvolimab", "type": "DRUG" }, { "name": "Matching Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Celldex Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 240, "start_date": "2026-01-15", "completion_date": "2028-10", "has_results": false, "last_update_posted_date": "2026-08-26", "last_synced_at": "2026-09-02T10:50:49.680Z", "location_count": 26, "location_summary": "Birmingham, Alabama • Scottsdale, Arizona • Bakersfield, California + 22 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Scottsdale", "state": "Arizona" }, { "city": "Bakersfield", "state": "California" }, { "city": "Napa", "state": "California" }, { "city": "Redwood City", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT07266402" }, { "nct_id": "NCT06445023", "title": "A Phase 3 Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Chronic Spontaneous Urticaria" ], "interventions": [ { "name": "barzolvolimab", "type": "BIOLOGICAL" }, { "name": "Matching placebo", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Celldex Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 963, "start_date": "2024-07-11", "completion_date": "2027-04", "has_results": false, "last_update_posted_date": "2026-03-25", "last_synced_at": "2026-09-02T10:50:49.680Z", "location_count": 58, "location_summary": "Birmingham, Alabama • Fountain Valley, California • Inglewood, California + 50 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Fountain Valley", "state": "California" }, { "city": "Inglewood", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06445023" }, { "nct_id": "NCT05405660", "title": "A Study of CDX-0159 in Patients With Chronic Inducible Urticaria", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Chronic Inducible Urticaria" ], "interventions": [ { "name": "barzolvolimab", "type": "BIOLOGICAL" }, { "name": "Matching Placebo", "type": "DRUG" } ], "intervention_types": [ "BIOLOGICAL", "DRUG" ], "sponsor": "Celldex Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 196, "start_date": "2022-06-28", "completion_date": "2025-09-12", "has_results": false, "last_update_posted_date": "2025-11-06", "last_synced_at": "2026-09-02T10:50:49.680Z", "location_count": 16, "location_summary": "Birmingham, Alabama • Montgomery, Alabama • Paradise Valley, Arizona + 13 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Montgomery", "state": "Alabama" }, { "city": "Paradise Valley", "state": "Arizona" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Bakersfield", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT05405660" }, { "nct_id": "NCT06366750", "title": "A Study of Barzolvolimab in Patients With Prurigo Nodularis", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Prurigo Nodularis" ], "interventions": [ { "name": "barzolvolimab", "type": "BIOLOGICAL" }, { "name": "Matching Placebo", "type": "OTHER" } ], "intervention_types": [ "BIOLOGICAL", "OTHER" ], "sponsor": "Celldex Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 140, "start_date": "2024-04-12", "completion_date": "2027-03", "has_results": false, "last_update_posted_date": "2026-08-04", "last_synced_at": "2026-09-02T10:50:49.680Z", "location_count": 37, "location_summary": "Birmingham, Alabama • Scottsdale, Arizona • Fremont, California + 30 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Birmingham", "state": "Alabama" }, { "city": "Scottsdale", "state": "Arizona" }, { "city": "Scottsdale", "state": "Arizona" }, { "city": "Fremont", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06366750" }, { "nct_id": "NCT05774184", "title": "A Study of CDX-0159 in Patients With Eosinophilic Esophagitis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Eosinophilic Esophagitis" ], "interventions": [ { "name": "barzolvolimab", "type": "BIOLOGICAL" }, { "name": "Matching Placebo", "type": "DRUG" } ], "intervention_types": [ "BIOLOGICAL", "DRUG" ], "sponsor": "Celldex Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 86, "start_date": "2023-06-01", "completion_date": "2026-01-23", "has_results": false, "last_update_posted_date": "2026-05-27", "last_synced_at": "2026-09-02T10:50:49.680Z", "location_count": 24, "location_summary": "Birmingham, Alabama • Scottsdale, Arizona • Sun City, Arizona + 20 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Scottsdale", "state": "Arizona" }, { "city": "Sun City", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Chula Vista", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT05774184" } ] }