{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Before+Initial+Treatment+Decision",
    "query": {
      "intervention": "Before Initial Treatment Decision"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 142,
    "total_pages": 15,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Before+Initial+Treatment+Decision&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-10T18:51:03.718Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06409247",
      "title": "iExposure Intervention for Social Anxiety",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Social Anxiety"
      ],
      "interventions": [
        {
          "name": "iExposure",
          "type": "BEHAVIORAL"
        },
        {
          "name": "iExposure plus attention guidance",
          "type": "BEHAVIORAL"
        },
        {
          "name": "iExposure plus attention control",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Palo Alto University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 390,
      "start_date": "2024-07-01",
      "completion_date": "2026-03-30",
      "has_results": false,
      "last_update_posted_date": "2026-03-09",
      "last_synced_at": "2026-09-10T18:51:03.718Z",
      "location_count": 1,
      "location_summary": "Palo Alto, California",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06409247"
    },
    {
      "nct_id": "NCT03919084",
      "title": "THRIVE+ Pharmacy Liaison-Patient Navigation Intervention",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthcare Utilization"
      ],
      "interventions": [
        {
          "name": "THRIVE screening and referral",
          "type": "OTHER"
        },
        {
          "name": "Pharmacy Care Program services",
          "type": "OTHER"
        },
        {
          "name": "Patient Navigation Services",
          "type": "OTHER"
        },
        {
          "name": "Motivational Interviewing",
          "type": "OTHER"
        },
        {
          "name": "Linkage to Community Partner Organization",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Boston Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "18 Years to 64 Years"
      },
      "enrollment_count": 364,
      "start_date": "2019-05-28",
      "completion_date": "2021-03-05",
      "has_results": false,
      "last_update_posted_date": "2021-03-18",
      "last_synced_at": "2026-09-10T18:51:03.718Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03919084"
    },
    {
      "nct_id": "NCT03217838",
      "title": "Safety, Tolerability, Pharmacokinetics, and Efficacy of AZD2811 Nanoparticles as Monotherapy or in Combination in Acute Myeloid Leukemia Participants.",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Acute Myeloid Leukaemia"
      ],
      "interventions": [
        {
          "name": "AZD2811",
          "type": "DRUG"
        },
        {
          "name": "Azacitidine",
          "type": "DRUG"
        },
        {
          "name": "Venetoclax",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "AstraZeneca",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "130 Years",
        "sex": "ALL",
        "summary": "18 Years to 130 Years"
      },
      "enrollment_count": 50,
      "start_date": "2017-07-31",
      "completion_date": "2021-03-25",
      "has_results": false,
      "last_update_posted_date": "2022-04-05",
      "last_synced_at": "2026-09-10T18:51:03.718Z",
      "location_count": 10,
      "location_summary": "Denver, Colorado • Sarasota, Florida • Detroit, Michigan + 7 more",
      "locations": [
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Sarasota",
          "state": "Florida"
        },
        {
          "city": "Detroit",
          "state": "Michigan"
        },
        {
          "city": "Charlotte",
          "state": "North Carolina"
        },
        {
          "city": "Canton",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03217838"
    },
    {
      "nct_id": "NCT00297492",
      "title": "Gradual vs. Abrupt Cessation Treatment for Smoking",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Smoking Cessation"
      ],
      "interventions": [
        {
          "name": "Reduction Phone Counseling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Abrupt Phone Counseling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Minimal Abrupt Phone Counseling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Pre-Quit Nicotine Lozenges",
          "type": "DRUG"
        },
        {
          "name": "Post-Quit Nicotine Lozenges",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DRUG"
      ],
      "sponsor": "University of Vermont",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 750,
      "start_date": "2006-01",
      "completion_date": "2008-02",
      "has_results": true,
      "last_update_posted_date": "2013-09-20",
      "last_synced_at": "2026-09-10T18:51:03.718Z",
      "location_count": 1,
      "location_summary": "Burlington, Vermont",
      "locations": [
        {
          "city": "Burlington",
          "state": "Vermont"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00297492"
    },
    {
      "nct_id": "NCT04790630",
      "title": "Cognitive Fitness for Depression in Older Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Depression Mild",
        "Depressive Disorder, Major",
        "Mild Cognitive Impairment"
      ],
      "interventions": [
        {
          "name": "Computerized Cognitive Remediation of Executive Functioning (CCR-EF)",
          "type": "OTHER"
        },
        {
          "name": "Active Control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "UConn Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 38,
      "start_date": "2020-11-15",
      "completion_date": "2024-10-15",
      "has_results": true,
      "last_update_posted_date": "2026-04-29",
      "last_synced_at": "2026-09-10T18:51:03.718Z",
      "location_count": 1,
      "location_summary": "Farmington, Connecticut",
      "locations": [
        {
          "city": "Farmington",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04790630"
    },
    {
      "nct_id": "NCT02204371",
      "title": "Evaluation of Pazopanib on Bleeding in Subjects With Hereditary Haemorrhagic Telangiectasia",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Telangiectasia, Hereditary Hemorrhagic"
      ],
      "interventions": [
        {
          "name": "Pazopanib",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "GlaxoSmithKline",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 7,
      "start_date": "2015-02-25",
      "completion_date": "2016-02-10",
      "has_results": true,
      "last_update_posted_date": "2017-07-06",
      "last_synced_at": "2026-09-10T18:51:03.718Z",
      "location_count": 5,
      "location_summary": "Los Angeles, California • Augusta, Georgia • St Louis, Missouri + 2 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Augusta",
          "state": "Georgia"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        },
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02204371"
    },
    {
      "nct_id": "NCT02422186",
      "title": "A Study to Evaluate the Efficacy, Safety, and Tolerability of Intranasal Esketamine Plus an Oral Antidepressant in Elderly Participants With Treatment-resistant Depression",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Depressive Disorder, Treatment-Resistant"
      ],
      "interventions": [
        {
          "name": "Esketamine",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "Duloxetine (Oral Antidepressant)",
          "type": "DRUG"
        },
        {
          "name": "Escitalopram (Oral Antidepressant)",
          "type": "DRUG"
        },
        {
          "name": "Sertraline (Oral Antidepressant)",
          "type": "DRUG"
        },
        {
          "name": "Venlafaxine Extended Release (XR) (New Antidepressant)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Janssen Research & Development, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 139,
      "start_date": "2015-08-20",
      "completion_date": "2017-08-10",
      "has_results": true,
      "last_update_posted_date": "2025-04-29",
      "last_synced_at": "2026-09-10T18:51:03.718Z",
      "location_count": 15,
      "location_summary": "San Diego, California • New Haven, Connecticut • Miami, Florida + 12 more",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Marietta",
          "state": "Georgia"
        },
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02422186"
    },
    {
      "nct_id": "NCT01120704",
      "title": "Evaluation of Treatments to Improve Smoking Cessation Medication Adherence",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Smoking",
        "Smoking Cessation",
        "Adherence",
        "Nicotine Dependence",
        "Motivation"
      ],
      "interventions": [
        {
          "name": "Short Term Combination Nicotine Replacement Therapy (patch + gum)",
          "type": "DRUG"
        },
        {
          "name": "Long Term Combination Nicotine Replacement Therapy (patch + gum)",
          "type": "DRUG"
        },
        {
          "name": "Intensive Maintenance Counseling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Cognitive Medication Adherence Counseling (CAM)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Electronic Medication Monitoring Device (the Helping Hand) + Feedback",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Automated Adherence Prompting Phone Calls",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 544,
      "start_date": "2010-06",
      "completion_date": "2014-05",
      "has_results": true,
      "last_update_posted_date": "2015-12-11",
      "last_synced_at": "2026-09-10T18:51:03.718Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01120704"
    },
    {
      "nct_id": "NCT03227068",
      "title": "Parent Educational Discharge Support Strategies",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Educational Activities"
      ],
      "interventions": [
        {
          "name": "PEDSS - symptom management",
          "type": "OTHER"
        },
        {
          "name": "PEDSS - support for the caregiver",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "3 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "3 Years to 17 Years"
      },
      "enrollment_count": 289,
      "start_date": "2017-12-29",
      "completion_date": "2020-06-29",
      "has_results": false,
      "last_update_posted_date": "2020-06-30",
      "last_synced_at": "2026-09-10T18:51:03.718Z",
      "location_count": 15,
      "location_summary": "Miami, Florida • Chicago, Illinois • Winfield, Illinois + 12 more",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Winfield",
          "state": "Illinois"
        },
        {
          "city": "Scarborough",
          "state": "Maine"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03227068"
    },
    {
      "nct_id": "NCT05352451",
      "title": "Values and Options in Cancer Care 2 (VOICE 2) A Randomized Pilot Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Communication, Multidisciplinary"
      ],
      "interventions": [
        {
          "name": "Interventional Survey",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Rutgers, The State University of New Jersey",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 29,
      "start_date": "2022-05-09",
      "completion_date": "2024-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-04-09",
      "last_synced_at": "2026-09-10T18:51:03.718Z",
      "location_count": 1,
      "location_summary": "New Brunswick, New Jersey",
      "locations": [
        {
          "city": "New Brunswick",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05352451"
    }
  ]
}