{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Biologic+Lung+Volume+Reduction", "query": { "intervention": "Biologic Lung Volume Reduction" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 7, "total_pages": 1, "next_page_url": null, "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-06T05:24:27.745Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT01505569", "title": "Auto Transplant for High Risk or Relapsed Solid or CNS Tumors", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Ewing's Family Tumors", "Renal Tumors", "Hepatoblastoma", "Rhabdomyosarcoma", "Soft Tissue Sarcoma", "Primary Malignant Brain Neoplasms", "Retinoblastoma", "Medulloblastoma", "Supra-tentorial Primative Neuro-Ectodermal Tumor (PNET)", "Atypical Teratoid/Rhabdoid Tumor (AT/RT)", "CNS Tumors", "Germ Cell Tumors" ], "interventions": [ { "name": "Ifosfamide", "type": "DRUG" }, { "name": "Etoposide", "type": "DRUG" }, { "name": "Mesna", "type": "DRUG" }, { "name": "G-CSF", "type": "BIOLOGICAL" }, { "name": "Busulfan", "type": "DRUG" }, { "name": "Melphalan", "type": "DRUG" }, { "name": "Thiotepa", "type": "DRUG" }, { "name": "Autologous stem cell infusion", "type": "BIOLOGICAL" }, { "name": "Radiation", "type": "RADIATION" }, { "name": "Carboplatin", "type": "DRUG" }, { "name": "Paclitaxel", "type": "DRUG" }, { "name": "Leukapheresis", "type": "PROCEDURE" }, { "name": "Anti-seizure prophylaxis", "type": "DRUG" }, { "name": "Ursodiol", "type": "DRUG" } ], "intervention_types": [ "DRUG", "BIOLOGICAL", "RADIATION", "PROCEDURE" ], "sponsor": "Masonic Cancer Center, University of Minnesota", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": "70 Years", "sex": "ALL", "summary": "Up to 70 Years" }, "enrollment_count": 44, "start_date": "2011-10-20", "completion_date": "2024-02-01", "has_results": false, "last_update_posted_date": "2024-02-26", "last_synced_at": "2026-09-06T05:24:27.745Z", "location_count": 1, "location_summary": "Minneapolis, Minnesota", "locations": [ { "city": "Minneapolis", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT01505569" }, { "nct_id": "NCT00630227", "title": "Biologic Lung Volume Reduction (BLVR) Phase 2 Homogeneous Study", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Homogeneous Emphysema" ], "interventions": [ { "name": "Biologic Lung Volume Reduction", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Aeris Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": null, "sex": "ALL", "summary": "40 Years and older" }, "enrollment_count": 33, "start_date": "2008-02", "completion_date": "2009-12", "has_results": false, "last_update_posted_date": "2011-10-24", "last_synced_at": "2026-09-06T05:24:27.745Z", "location_count": 8, "location_summary": "Birmingham, Alabama • Phoenix, Arizona • Iowa City, Iowa + 5 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Iowa City", "state": "Iowa" }, { "city": "Topeka", "state": "Kansas" }, { "city": "Towson", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT00630227" }, { "nct_id": "NCT00795132", "title": "Hematopoietic Cell Transplantation for Pediatric Patients With Hematologic Malignancies", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Acute Leukaemia", "Chronic Disease", "Leukemia", "Myelodysplasia", "Lymphoma" ], "interventions": [ { "name": "Busulfan", "type": "DRUG" }, { "name": "Anti-Thymocyte Globulin", "type": "DRUG" }, { "name": "Fludarabine", "type": "DRUG" }, { "name": "Cyclosporine", "type": "DRUG" }, { "name": "Mycophenolate mofetil", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Utah", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": "21 Years", "sex": "ALL", "summary": "Up to 21 Years" }, "enrollment_count": 47, "start_date": "2004-04", "completion_date": "2009-07", "has_results": true, "last_update_posted_date": "2013-07-30", "last_synced_at": "2026-09-06T05:24:27.745Z", "location_count": 1, "location_summary": "Salt Lake City, Utah", "locations": [ { "city": "Salt Lake City", "state": "Utah" } ], "official_url": "https://clinicaltrials.gov/study/NCT00795132" }, { "nct_id": "NCT03911856", "title": "Unmasking Right Ventricular and Pulmonary Derangements With Exercise and Oxygen in Early Stage Cardiopulmonary Diseases", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Cardiopulmonary Disease" ], "interventions": [ { "name": "Echocardiography", "type": "OTHER" }, { "name": "Pulmonary Gas Exchange", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Mayo Clinic", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 7, "start_date": "2020-01-09", "completion_date": "2024-01-16", "has_results": false, "last_update_posted_date": "2024-03-12", "last_synced_at": "2026-09-06T05:24:27.745Z", "location_count": 1, "location_summary": "Rochester, Minnesota", "locations": [ { "city": "Rochester", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT03911856" }, { "nct_id": "NCT00347659", "title": "US 10 mL Biologic Lung Volume Reduction (BLVR) Phase 1 Emphysema Study", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Pulmonary Emphysema" ], "interventions": [ { "name": "BLVR System", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Aeris Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": null, "sex": "ALL", "summary": "40 Years and older" }, "enrollment_count": 6, "start_date": "2006-06", "completion_date": "2007-09", "has_results": false, "last_update_posted_date": "2008-03-06", "last_synced_at": "2026-09-06T05:24:27.745Z", "location_count": 2, "location_summary": "Boston, Massachusetts • Philadelphia, Pennsylvania", "locations": [ { "city": "Boston", "state": "Massachusetts" }, { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT00347659" }, { "nct_id": "NCT00515164", "title": "US Biologic Lung Volume Reduction (BLVR) Phase 2 Emphysema Study", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Pulmonary Emphysema", "Chronic Obstructive Pulmonary Disease" ], "interventions": [ { "name": "Biologic Lung Volume Reduction (BLVR) - 20 mL Hydrogel", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Aeris Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": null, "sex": "ALL", "summary": "40 Years and older" }, "enrollment_count": 22, "start_date": "2007-08", "completion_date": "2009-12", "has_results": false, "last_update_posted_date": "2011-10-24", "last_synced_at": "2026-09-06T05:24:27.745Z", "location_count": 8, "location_summary": "Phoenix, Arizona • Iowa City, Iowa • Topeka, Kansas + 5 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Iowa City", "state": "Iowa" }, { "city": "Topeka", "state": "Kansas" }, { "city": "Towson", "state": "Maryland" }, { "city": "Akron", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT00515164" }, { "nct_id": "NCT00435253", "title": "US 10 mL Biologic Lung Volume Reduction (BLVR) Phase 2 Emphysema Study", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Pulmonary Emphysema" ], "interventions": [ { "name": "BLVR Treatment", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Aeris Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": null, "sex": "ALL", "summary": "40 Years and older" }, "enrollment_count": 20, "start_date": "2007-02", "completion_date": "2009-06", "has_results": false, "last_update_posted_date": "2011-10-24", "last_synced_at": "2026-09-06T05:24:27.745Z", "location_count": 5, "location_summary": "Birmingham, Alabama • Phoenix, Arizona • Boston, Massachusetts + 2 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "Philadelphia", "state": "Pennsylvania" }, { "city": "Charleston", "state": "South Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT00435253" } ] }