{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Biomarker-based+adjustment",
    "query": {
      "intervention": "Biomarker-based adjustment"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 13,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Biomarker-based+adjustment&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-13T02:03:30.124Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07812987",
      "title": "Rapid Entrainment and Signal-guided Neuromodulation for Behavioral Health",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anxiety",
        "PTSD",
        "ADHD",
        "Depression Disorders",
        "Post-traumatic Stress",
        "Substance Use",
        "Executive Function",
        "Sleep Disturbance"
      ],
      "interventions": [
        {
          "name": "AIP-Informed Integrative Psychotherapy",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Transcutaneous Auricular Vagus Nerve Stimulation",
          "type": "DEVICE"
        },
        {
          "name": "Regulated Breathing and Autonomic Regulation",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Audiovisual Entrainment",
          "type": "DEVICE"
        },
        {
          "name": "Vibroacoustic Stimulation",
          "type": "DEVICE"
        },
        {
          "name": "Breathwork-Based Auditory Driving Entropy Module (BADEM)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Transcranial Electrical Stimulation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DEVICE"
      ],
      "sponsor": "Tactical Mind Research Coalition, Inc.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 240,
      "start_date": "2026-08-01",
      "completion_date": "2028-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-09-10",
      "last_synced_at": "2026-09-13T02:03:30.124Z",
      "location_count": 1,
      "location_summary": "Tampa, Florida",
      "locations": [
        {
          "city": "Tampa",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07812987"
    },
    {
      "nct_id": "NCT03852537",
      "title": "Steroid Dosing by bioMARker Guided Titration in Critically Ill Patients With Pneumonia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Pneumonia"
      ],
      "interventions": [
        {
          "name": "Methylprednisolone",
          "type": "DRUG"
        },
        {
          "name": "Usual Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 44,
      "start_date": "2019-12-02",
      "completion_date": "2020-11-17",
      "has_results": true,
      "last_update_posted_date": "2021-09-16",
      "last_synced_at": "2026-09-13T02:03:30.124Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03852537"
    },
    {
      "nct_id": "NCT07434986",
      "title": "Overnight TI in TLE",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Temporal Lobe Epilepsy (TLE)",
        "Drug Resistant Epilepsy",
        "Sleep"
      ],
      "interventions": [
        {
          "name": "Non-invasive Temporal Interference (TI) Stimulation Targeting Bilateral Hippocampi",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 20,
      "start_date": "2026-06-01",
      "completion_date": "2026-10-30",
      "has_results": false,
      "last_update_posted_date": "2026-05-12",
      "last_synced_at": "2026-09-13T02:03:30.124Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07434986"
    },
    {
      "nct_id": "NCT02395289",
      "title": "Cognitive-Based Compassion Training (CBCT) for People Living With HIV (PLHIV)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Human Immunodeficiency Virus"
      ],
      "interventions": [
        {
          "name": "Cognitive-Based Compassion Training (CBCT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Health discussion",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 54,
      "start_date": "2016-03",
      "completion_date": "2016-12",
      "has_results": false,
      "last_update_posted_date": "2017-02-01",
      "last_synced_at": "2026-09-13T02:03:30.124Z",
      "location_count": 1,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02395289"
    },
    {
      "nct_id": "NCT00496782",
      "title": "Multicenter Pilot Study To Define The Marker As An Alternate For Tropism Assay",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "HIV Infections"
      ],
      "interventions": [
        {
          "name": "maraviroc",
          "type": "DRUG"
        },
        {
          "name": "Trofile Assay and HIV RNA quantification assay",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "ViiV Healthcare",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "16 Years and older"
      },
      "enrollment_count": 16,
      "start_date": "2007-07",
      "completion_date": "2008-10",
      "has_results": true,
      "last_update_posted_date": "2019-01-30",
      "last_synced_at": "2026-09-13T02:03:30.124Z",
      "location_count": 9,
      "location_summary": "Miami, Florida • Chicago, Illinois • Topeka, Kansas + 5 more",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Topeka",
          "state": "Kansas"
        },
        {
          "city": "Topeka",
          "state": "Kansas"
        },
        {
          "city": "Detroit",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00496782"
    },
    {
      "nct_id": "NCT07204184",
      "title": "Multisite Transspinal Stimulation for Augmenting Recovery in Spinal Cord Injury",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Spinal Cord Injuries (Complete and Incomplete)"
      ],
      "interventions": [
        {
          "name": "Multisite transspinal stimulation at rest",
          "type": "DEVICE"
        },
        {
          "name": "Multisite transspinal stimulation during robotic gait training",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Maria Knikou, PT, MBA, PhD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 36,
      "start_date": "2026-02-19",
      "completion_date": "2028-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-03-18",
      "last_synced_at": "2026-09-13T02:03:30.124Z",
      "location_count": 1,
      "location_summary": "Staten Island, New York",
      "locations": [
        {
          "city": "Staten Island",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07204184"
    },
    {
      "nct_id": "NCT03521180",
      "title": "A Study to Evaluate Gluten Challenge on Immune Responses in Subjects With Celiac Disease",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Celiac Disease"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Celgene",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 5,
      "start_date": "2018-05-11",
      "completion_date": "2019-07-18",
      "has_results": false,
      "last_update_posted_date": "2020-02-26",
      "last_synced_at": "2026-09-13T02:03:30.124Z",
      "location_count": 2,
      "location_summary": "Dallas, Texas • Seattle, Washington",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03521180"
    },
    {
      "nct_id": "NCT00495157",
      "title": "Asthma Clinical Research Network (ACRN) Trial - Best Adjustment Strategy for Asthma in Long Term (BASALT)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Asthma"
      ],
      "interventions": [
        {
          "name": "Symptom-based adjustment",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Biomarker-based adjustment",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Guideline-based adjustment",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Milton S. Hershey Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 342,
      "start_date": "2007-06",
      "completion_date": "2010-07",
      "has_results": true,
      "last_update_posted_date": "2013-04-11",
      "last_synced_at": "2026-09-13T02:03:30.124Z",
      "location_count": 10,
      "location_summary": "San Diego, California • San Francisco, California • Denver, Colorado + 7 more",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00495157"
    },
    {
      "nct_id": "NCT06266455",
      "title": "Individualized Nutrition to Optimize Preterm Infant Growth and Neurodevelopment",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Very Preterm Maturity of Infant",
        "Very Low Birth Weight Infant"
      ],
      "interventions": [
        {
          "name": "Standardized Fortification",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Adjustable Fortification",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Children's National Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "4 Weeks",
        "sex": "ALL",
        "summary": "Up to 4 Weeks"
      },
      "enrollment_count": 150,
      "start_date": "2024-02-08",
      "completion_date": "2034-01",
      "has_results": false,
      "last_update_posted_date": "2025-07-11",
      "last_synced_at": "2026-09-13T02:03:30.124Z",
      "location_count": 1,
      "location_summary": "Washington D.C., District of Columbia",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06266455"
    },
    {
      "nct_id": "NCT03044353",
      "title": "Multiple Treatment Session Study to Assess GSK2398852 Administered Following and Along With GSK2315698",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Amyloidosis"
      ],
      "interventions": [
        {
          "name": "GSK2315698 (CPHPC)",
          "type": "DRUG"
        },
        {
          "name": "GSK2398852 (anti-SAP mAb)",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BIOLOGICAL"
      ],
      "sponsor": "GlaxoSmithKline",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 7,
      "start_date": "2017-07-10",
      "completion_date": "2019-01-03",
      "has_results": true,
      "last_update_posted_date": "2019-10-16",
      "last_synced_at": "2026-09-13T02:03:30.124Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03044353"
    }
  ]
}