{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Bispectral+Index+%28BIS%29+Monitor",
    "query": {
      "intervention": "Bispectral Index (BIS) Monitor"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 18,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Bispectral+Index+%28BIS%29+Monitor&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-25T11:32:06.192Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03133845",
      "title": "Shaping Anesthetic Techniques to Reduce Post-operative Delirium",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Delirium",
        "Lumbar Radiculopathy",
        "Lumbar Osteoarthritis",
        "Lumbar Spine Disc Degeneration"
      ],
      "interventions": [
        {
          "name": "Light sedation with propofol",
          "type": "PROCEDURE"
        },
        {
          "name": "Induction with propofol",
          "type": "PROCEDURE"
        },
        {
          "name": "Maintenance anesthetic using a volatile anesthetic",
          "type": "PROCEDURE"
        },
        {
          "name": "Muscle relaxant during maintenance anesthesia",
          "type": "PROCEDURE"
        },
        {
          "name": "Pain control with fentanyl",
          "type": "PROCEDURE"
        },
        {
          "name": "Bispectral Index (BIS) monitoring for depth of anesthesia",
          "type": "PROCEDURE"
        },
        {
          "name": "Spinal Anesthesia",
          "type": "PROCEDURE"
        },
        {
          "name": "Midazolam administered during spinal anesthesia",
          "type": "PROCEDURE"
        },
        {
          "name": "Cerebrospinal fluid collection",
          "type": "PROCEDURE"
        },
        {
          "name": "Administration of intrathecal morphine",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 218,
      "start_date": "2015-10",
      "completion_date": "2020-05-25",
      "has_results": false,
      "last_update_posted_date": "2020-06-18",
      "last_synced_at": "2026-09-25T11:32:06.192Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03133845"
    },
    {
      "nct_id": "NCT04062240",
      "title": "Bispectral Index: A Comparison of Bifrontal Montage Agreement",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Surgery",
        "Bispectral Index"
      ],
      "interventions": [
        {
          "name": "BIS sensor",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 15,
      "start_date": "2019-11-27",
      "completion_date": "2021-10-01",
      "has_results": true,
      "last_update_posted_date": "2023-02-21",
      "last_synced_at": "2026-09-25T11:32:06.192Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04062240"
    },
    {
      "nct_id": "NCT01187420",
      "title": "Bilateral Bispectral Index (BIS) Study",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cerebral Vasospasm",
        "Delayed Cerebral Ischemia",
        "Subarachnoid Hemorrhage"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Icahn School of Medicine at Mount Sinai",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2009-06",
      "completion_date": "2010-10",
      "has_results": false,
      "last_update_posted_date": "2017-02-13",
      "last_synced_at": "2026-09-25T11:32:06.192Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01187420"
    },
    {
      "nct_id": "NCT01377636",
      "title": "Measurement of Bispectral Index and Awareness in Patients Undergoing Electrophysiology Studies With Isoproterenol",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Intraoperative Awareness"
      ],
      "interventions": [
        {
          "name": "Isoproterenol",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "NYU Langone Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2009-08",
      "completion_date": "2011-10",
      "has_results": true,
      "last_update_posted_date": "2015-02-23",
      "last_synced_at": "2026-09-25T11:32:06.192Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01377636"
    },
    {
      "nct_id": "NCT00689091",
      "title": "Bispectral Index (BIS) Versus Electronic Alerts in the Prevention of Anesthesia Awareness: the Michigan Awareness Control Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Awareness During General Anesthesia"
      ],
      "interventions": [
        {
          "name": "Bispectral Index Monitor",
          "type": "DEVICE"
        },
        {
          "name": "Electronic MAC alert",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 22185,
      "start_date": "2008-05",
      "completion_date": "2010-06",
      "has_results": true,
      "last_update_posted_date": "2017-12-07",
      "last_synced_at": "2026-09-25T11:32:06.192Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00689091"
    },
    {
      "nct_id": "NCT04602546",
      "title": "Evaluation of Bispectral Index (BIS™) and Levels of Sedation With Common Inhalational Anesthetics in Healthy Volunteers (OLIVER)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anesthesia"
      ],
      "interventions": [
        {
          "name": "BIS Complete Monitoring System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Medtronic - MITG",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 211,
      "start_date": "2021-02-09",
      "completion_date": "2022-08-26",
      "has_results": true,
      "last_update_posted_date": "2023-04-18",
      "last_synced_at": "2026-09-25T11:32:06.192Z",
      "location_count": 3,
      "location_summary": "San Francisco, California • Durham, North Carolina • Salt Lake City, Utah",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        },
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04602546"
    },
    {
      "nct_id": "NCT03962036",
      "title": "Effect of One-lung Ventilation on BIS Values",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Surgery",
        "Thoracic"
      ],
      "interventions": [
        {
          "name": "Bispectral index monitor",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Christopher McKee",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 8,
      "start_date": "2019-10-11",
      "completion_date": "2021-12-03",
      "has_results": false,
      "last_update_posted_date": "2021-12-20",
      "last_synced_at": "2026-09-25T11:32:06.192Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03962036"
    },
    {
      "nct_id": "NCT01850017",
      "title": "Study of Dexmedetomidine in Spine Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Collapse of Thoracic Vertebra",
        "Collapse of Lumbar Vertebrae"
      ],
      "interventions": [
        {
          "name": "Dexmedetomidine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Virginia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 142,
      "start_date": "2012-08",
      "completion_date": "2015-05",
      "has_results": false,
      "last_update_posted_date": "2017-05-05",
      "last_synced_at": "2026-09-25T11:32:06.192Z",
      "location_count": 1,
      "location_summary": "Charlottesville, Virginia",
      "locations": [
        {
          "city": "Charlottesville",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01850017"
    },
    {
      "nct_id": "NCT03052543",
      "title": "Outcomes of an Intraoperative Bispectral Index Monitor",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Anesthesia"
      ],
      "interventions": [
        {
          "name": "BIS™ Complete 2--Channel Monitor",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": "12 Years",
        "sex": "ALL",
        "summary": "2 Years to 12 Years"
      },
      "enrollment_count": 60,
      "start_date": "2018-03-07",
      "completion_date": "2019-10-11",
      "has_results": false,
      "last_update_posted_date": "2020-10-14",
      "last_synced_at": "2026-09-25T11:32:06.192Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03052543"
    },
    {
      "nct_id": "NCT01173263",
      "title": "Effect of Bispectral Index (BIS) Titrated Propofol Sedation on Lower Esophageal Sphincter Pressures and Esophageal Function in Intensive Care Patients",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Respiration, Artificial"
      ],
      "interventions": [
        {
          "name": "BIS 70 maintained",
          "type": "OTHER"
        },
        {
          "name": "BIS level 50",
          "type": "OTHER"
        },
        {
          "name": "BIS 35",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "The Cleveland Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 1,
      "start_date": "2010-07",
      "completion_date": "2011-03",
      "has_results": false,
      "last_update_posted_date": "2014-03-05",
      "last_synced_at": "2026-09-25T11:32:06.192Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01173263"
    }
  ]
}