{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Blood+Pressure+and+Heart+Rate",
    "query": {
      "intervention": "Blood Pressure and Heart Rate"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 346,
    "total_pages": 35,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Blood+Pressure+and+Heart+Rate&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-26T03:39:09.100Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05357040",
      "title": "Antidepressant Effects of Nitrous Oxide",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Major Depressive Disorder",
        "Treatment Resistant Depression"
      ],
      "interventions": [
        {
          "name": "Nitrous oxide gas for inhalation",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2021-06-30",
      "completion_date": "2026-02-27",
      "has_results": false,
      "last_update_posted_date": "2026-05-14",
      "last_synced_at": "2026-09-26T03:39:09.100Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05357040"
    },
    {
      "nct_id": "NCT00464490",
      "title": "Use of Dexmedetomidine to Facilitate Extubation in Surgical ICU Patients Who Failed Previous Weaning Attempts",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Intubation; Difficult",
        "Respiration Disorders"
      ],
      "interventions": [
        {
          "name": "Dexmedetomidine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "69 Years",
        "sex": "ALL",
        "summary": "18 Years to 69 Years"
      },
      "enrollment_count": 42,
      "start_date": "2007-11",
      "completion_date": "2012-12",
      "has_results": true,
      "last_update_posted_date": "2014-10-31",
      "last_synced_at": "2026-09-26T03:39:09.100Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00464490"
    },
    {
      "nct_id": "NCT02791568",
      "title": "Advanced MRI for Uteroplacental Flow, Perfusion, Oxygenation & Inflammation",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Pregnancy",
        "Obesity",
        "Preeclampsia"
      ],
      "interventions": [
        {
          "name": "Ultrasound Scan",
          "type": "PROCEDURE"
        },
        {
          "name": "MRI Scan",
          "type": "PROCEDURE"
        },
        {
          "name": "Ferumoxytol",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 35 Years · Female only"
      },
      "enrollment_count": 121,
      "start_date": "2017-01-31",
      "completion_date": "2020-07-31",
      "has_results": false,
      "last_update_posted_date": "2025-08-22",
      "last_synced_at": "2026-09-26T03:39:09.100Z",
      "location_count": 2,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        },
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02791568"
    },
    {
      "nct_id": "NCT04679818",
      "title": "Postoperative Consequences of Intraoperative NOL Titration",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Anesthesia; Adverse Effect"
      ],
      "interventions": [
        {
          "name": "Routine opioid management",
          "type": "DRUG"
        },
        {
          "name": "PMD-200 Nol-guided opioid administration",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "The Cleveland Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "21 Years to 85 Years"
      },
      "enrollment_count": 72,
      "start_date": "2020-12-30",
      "completion_date": "2023-01-10",
      "has_results": true,
      "last_update_posted_date": "2024-06-21",
      "last_synced_at": "2026-09-26T03:39:09.100Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04679818"
    },
    {
      "nct_id": "NCT04075279",
      "title": "Heart at Work Study",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Occupational Diseases",
        "Cardiovascular Diseases",
        "Cardiovascular Risk Factor",
        "Occupational Exposure"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": "59 Years",
        "sex": "MALE",
        "summary": "35 Years to 59 Years · Male only"
      },
      "enrollment_count": 19,
      "start_date": "2019-10-17",
      "completion_date": "2020-07-24",
      "has_results": true,
      "last_update_posted_date": "2021-05-03",
      "last_synced_at": "2026-09-26T03:39:09.100Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04075279"
    },
    {
      "nct_id": "NCT02551640",
      "title": "Improving Physical Activity Through a mHealth Intervention in Cardio-metabolic Risk Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetes Mellitus, Type 2",
        "Prediabetic State",
        "Hypertension",
        "Prehypertension",
        "Obesity"
      ],
      "interventions": [
        {
          "name": "FeatForward App (on study smartphone)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 300,
      "start_date": "2015-09",
      "completion_date": "2019-12",
      "has_results": false,
      "last_update_posted_date": "2020-09-01",
      "last_synced_at": "2026-09-26T03:39:09.100Z",
      "location_count": 2,
      "location_summary": "Charlestown, Massachusetts • Revere, Massachusetts",
      "locations": [
        {
          "city": "Charlestown",
          "state": "Massachusetts"
        },
        {
          "city": "Revere",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02551640"
    },
    {
      "nct_id": "NCT00724217",
      "title": "Standard Process 21 Day Purification Program Project",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Hyperlipidemia"
      ],
      "interventions": [
        {
          "name": "Standard Process 21 Day Purification Program (SPPP)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Logan College of Chiropractic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 40,
      "start_date": "2008-07",
      "completion_date": "2009-03",
      "has_results": false,
      "last_update_posted_date": "2008-07-29",
      "last_synced_at": "2026-09-26T03:39:09.100Z",
      "location_count": 1,
      "location_summary": "Chesterfield, Missouri",
      "locations": [
        {
          "city": "Chesterfield",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00724217"
    },
    {
      "nct_id": "NCT02725060",
      "title": "Autoimmune Basis for Postural Tachycardia Syndrome",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Postural Orthostatic Tachycardia Syndrome",
        "Postural Tachycardia Syndrome",
        "Tachycardia",
        "Arrhythmias, Cardiac",
        "Autonomic Nervous System Diseases",
        "Orthostatic Intolerance",
        "Cardiovascular Diseases",
        "Primary Dysautonomias"
      ],
      "interventions": [
        {
          "name": "phenylephrine",
          "type": "DRUG"
        },
        {
          "name": "isoproterenol",
          "type": "DRUG"
        },
        {
          "name": "25 micro-Ci of radiation",
          "type": "RADIATION"
        },
        {
          "name": "Posture study with blood samples",
          "type": "PROCEDURE"
        },
        {
          "name": "24-hour heart rhythm and blood pressure monitoring",
          "type": "PROCEDURE"
        },
        {
          "name": "Quantitative Axonal Sudomotor Reflex Testing",
          "type": "PROCEDURE"
        },
        {
          "name": "Autonomic function tests",
          "type": "PROCEDURE"
        },
        {
          "name": "Rebreathing test",
          "type": "OTHER"
        },
        {
          "name": "Assessment of splanchnic capacitance",
          "type": "OTHER"
        },
        {
          "name": "microneurography",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "RADIATION",
        "PROCEDURE",
        "OTHER"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 58,
      "start_date": "2016-02",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2025-11-12",
      "last_synced_at": "2026-09-26T03:39:09.100Z",
      "location_count": 2,
      "location_summary": "Oklahoma City, Oklahoma • Nashville, Tennessee",
      "locations": [
        {
          "city": "Oklahoma City",
          "state": "Oklahoma"
        },
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02725060"
    },
    {
      "nct_id": "NCT05077293",
      "title": "Building Electronic Tools To Enhance and Reinforce Cardiovascular Recommendations - Heart Failure",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Heart Failure",
        "Heart Failure With Reduced Ejection Fraction"
      ],
      "interventions": [
        {
          "name": "Best Practice Alert (BPA)",
          "type": "OTHER"
        },
        {
          "name": "In-Basket Message",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "NYU Langone Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 596,
      "start_date": "2021-09-09",
      "completion_date": "2022-01-01",
      "has_results": false,
      "last_update_posted_date": "2022-10-28",
      "last_synced_at": "2026-09-26T03:39:09.100Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05077293"
    },
    {
      "nct_id": "NCT03534934",
      "title": "CT-Based Modeling of Bone Micro-Architecture and Fracture-Risk in COPD",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pulmonary Disease, Chronic Obstructive",
        "Osteoporosis"
      ],
      "interventions": [
        {
          "name": "Vital signs",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Urine Pregnancy Test",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Questionnaires",
          "type": "OTHER"
        },
        {
          "name": "Blood Test",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Duel-energy X-ray absorptiometry scan",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Multi-detector computed tomography",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Dual-energy X-ray absorptiometry scan",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST",
        "OTHER"
      ],
      "sponsor": "Punam K Saha",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "45 Years to 90 Years"
      },
      "enrollment_count": 560,
      "start_date": "2019-02-26",
      "completion_date": "2025-03-19",
      "has_results": false,
      "last_update_posted_date": "2026-01-28",
      "last_synced_at": "2026-09-26T03:39:09.100Z",
      "location_count": 2,
      "location_summary": "Iowa City, Iowa • New York, New York",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03534934"
    }
  ]
}